Results 81 to 90 of about 706,552 (306)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Ottoman Sultan Abdul Aziz’s State Visit to Britain (July 1867): A Case in Negotiated ‘Ornamental’ Diplomatic Gifts

open access: yesRevue Française de Civilisation Britannique
This article examines gift-giving during Ottoman Sultan Abdul Aziz’s State visit to Britain in July 1867. An exceptional occasion in itself – for an Ottoman Sultan had never left his Empire in peacetime or ever would again –, the visit offers an ...
Stéphanie Prévost
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Okulda Hediye Sürecine İlişkin Yönetici ve Öğretmen Görüşleri

open access: yesAnkara Üniversitesi Eğitim Bilimleri Fakültesi Dergisi, 2021
Bu araştırmada Türkiye’deki kamu ve özel okullarda öğrenci ve velilerin öğretmenlere hediye verme davranışlarının derinlemesine incelenmesi amaçlanmıştır.
İnayet Aydın   +3 more
doaj  

Giving To Ingrates? [PDF]

open access: yes
Models for voluntary provision of public goods predict free riding is rational unless the model includes a motive for the act of giving referred to as a “warm glow” in the literature.
Michael Jones, Michael McKee
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Ritual, Not Material Objects: Living Organ Transplantation from the Perspective of Gift-Giving in Confucian Thought

open access: yesYixue yu zhexue
Living organ transplantation requires ethical reflection on the relational dynamics embedded behind the flow of organs. In the Confucian concept of gift-giving, living organs are regarded as ritual gifts rather than mere objects, reflecting the ethical ...
Yan ZHANG, Rui DENG
doaj   +1 more source

The Economics of the Gift [PDF]

open access: yes
gift-giving;reciprocity;adequacy;social approval.
Ven, J. van de
core   +1 more source

Home - About - Disclaimer - Privacy