Results 71 to 80 of about 59,120 (304)

Dressed in a Present from the Past: The Transfers and Transformations of a Swedish Bridal Crown in the United States

open access: yesCulture Unbound: Journal of Current Cultural Research, 2010
Ever since the emigration from the Nordic countries the Old world and the New world have maintained an exchange of ideas, customs, and material culture. This cultural heritage consists of more than remnants of the past.
Lizette Grad én
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The Effect of Optimal Discounting on Bundle Preference In Gift-giving Context

open access: yes, 2018
Bundling is the joint sale of two or more separate products at a single price, often discounted. When decision makers are faced with a bundle choice, they can opt to either purchase the bundle or any of its separate products.
Omebere-Iyari, D.
core  

Gifts to Whom? Towards a Network View of Gift Receivers

open access: yes
Purpose: This research aims to understand how givers characterise and manage their gift giving networks by drawing on attachment theory. This responds to the need to illuminate the givers-receivers’ networks beyond traditional role-based taxonomies and ...
Branco-Illodo, Ines   +2 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

The language of giving: Eid rituals and gift-giving practices among Saudi Gen Z

open access: yesCogent Arts & Humanities
Gift-giving during Eid has evolved in Saudi Arabia from a simple act of generosity into a socially structured ritual shaped by cultural expectations and linguistic conventions.
Albandary Ibrahim Alhammad
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Feeling Poor, Acting Stingy: the effect of money perception on charitable giving [PDF]

open access: yes, 2011
In research on philanthropy, much attention has been given to the impact of the actual economic costs of giving. This paper argues that the perceived psychological costs of giving should also be taken into consideration when seeking to understand ...
Pamala Wiepking   +5 more
core   +1 more source

The influence of relationship beliefs on gift giving

open access: yesManagement şi Marketing, 2017
People have fundamental beliefs about what constitutes a good relationship, known as implicit theories of relationship, where some people have destiny beliefs whereas others have growth beliefs. People with destiny beliefs believe that potential partners
Rai Dipankar   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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