Results 71 to 80 of about 1,142,752 (291)
Diabetes Spectrum, 2003 Editor’s note: This article is adapted from the address of the American Diabetes Association President, Health Care and Education, given in June 2003 at the 63rd Annual Meeting and Scientific Sessions in New Orleans, La. I have been asked many times over the past 12 months what I am going to do when my year in this role has ended.
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Transformational philanthropy and networks of cocreated value in Canada [PDF]
, 2011 This research discusses transformational philanthropy and networks of cocreated value in Canada, focusing on the top segment Canadian philanthropists who make single donations of $5 Million CAD or more.
Abray-Nyman, Jacline
core +3 more sources
Assessing the Link Between a Public University’s Brand-Building Activities and Alumni Gift-Giving
Marketing Management Journal, 2016 This study examines individualized alumnus gift-giving behaviors. It explores the link between alumnus traits such as age, gender, participation in fraternities or sororities, and college major with a university's brand-building activities and alumnus ...
YOUNG HAN BAE +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Online Surprise Gift-giving Services and Wellbeing: Sender and Recipient Perspectives
Purpose. Technology-mediated gift giving is prevailing as consumers seek convenience and novelty. Using an industry example, we explored how a subscription-based online gift-giving service contributes to the recipient’s wellbeing, both from sender and ...
Gregory-Smith, D. +3 more
core +1 more source
Culture Unbound: Journal of Current Cultural Research, 2010 Ever since the emigration from the Nordic countries the Old world and the New world have maintained an exchange of ideas, customs, and material culture. This cultural heritage consists of more than remnants of the past.
Lizette Grad én
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
The language of giving: Eid rituals and gift-giving practices among Saudi Gen Z
Cogent Arts & HumanitiesGift-giving during Eid has evolved in Saudi Arabia from a simple act of generosity into a socially structured ritual shaped by cultural expectations and linguistic conventions.
Albandary Ibrahim Alhammad
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source