Results 71 to 80 of about 706,552 (306)

If You Must Give Them a Gift, Then Give Them the Gift of Nonexistence

open access: yesCambridge Quarterly of Healthcare Ethics, 2022
AbstractI present a qualified new defense of antinatalism. It is intended to empower potential parents who worry about their possible children’s life quality in a world threatened by environmental degradation, climate change, and the like. The main elements of the defense are an understanding of antinatalism’s historical nature and contemporary ...
openaire   +4 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Gift-giving, Quasi-Credit and Reciprocity [PDF]

open access: yes
The fluctuations in incomes inherent in rural communities can be attenuated by reciprocal assistance. A model of reciprocal assistance based upon rational action and voluntary participation is presented.
Jonathan P. Thomas, Tim Worrall
core  

Here's something you never asked for, didn't know existed, and can't easily obtain: a search model of gift giving [PDF]

open access: yes, 2013
Draft version entitled "Here's something you never asked for, didn't know existed, and can't easily obtain: a search model of gift giving" dated August 2008 submitted to SSRN working paper series. Final version published by Elsevier.
Kaplan, Todd R., Ruffle, Bradley J.
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The influence of relationship beliefs on gift giving

open access: yesManagement şi Marketing, 2017
People have fundamental beliefs about what constitutes a good relationship, known as implicit theories of relationship, where some people have destiny beliefs whereas others have growth beliefs. People with destiny beliefs believe that potential partners
Rai Dipankar   +3 more
doaj   +1 more source

Stott\u27s The grace of giving and Wright\u27s The gift of accountability (Book Review)

open access: yes, 2016
A review of Stott, J. (2016). The grace of giving: 10 principles of Christian giving. Peabody, MA: Hendrickson Publishers. 33 pp. ISBN 9781598568738 and Wright, C. J. H. (2016).
Roberts, Paul
core   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Peer effects, risk pooling, and status seeking: What explains gift spending escalation in rural China? [PDF]

open access: yes
It has been widely documented that the poor spend a significant proportion of their income on gifts even at the expense of basic consumption. We test three competing explanations of this phenomenon—peer effect, status concern, and risk pooling—based on a
Chen, Xi, Kanbur, Ravi, Zhang, Xiaobo
core  

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