Results 1 to 10 of about 48,971 (154)
Effects of Gilbert syndrome on cardiovascular disease risk reduction: a systematic review [PDF]
The Egyptian Heart JournalBackground Gilbert syndrome is a human genetic disorder which affects bilirubin metabolism in the liver and results in unconjugated hyperbilirubinemia.
Nicola Churchill +2 more
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Development of a Physiologically Based Model of Bilirubin Metabolism in Health and Disease and Its Comparison With Real‐World Data [PDF]
CPT: Pharmacometrics & Systems PharmacologyBilirubin is a breakdown product of erythrocytes and plays a crucial role in elimination of heme‐containing proteins. After its synthesis in the reticuloendothelial system, unconjugated bilirubin is released into plasma and taken up into the liver.
Ahenk Zeynep Sayin, Lars Kuepfer
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Rethinking hyperbilirubinemia: Gilbert syndrome in children with cystic fibrosis, a case report [PDF]
Respiratory Medicine Case ReportsCystic Fibrosis leads to liver complications, including cystic fibrosis liver disease but hyperbilirubinemia in CF patients on CFTR modulators is less understood.
Yara Salameh, John Lyles, Shatha Yousef
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BMJ Medicine, 2023 Objectives To compare associations between the Gilbert syndrome genotype in European populations, measured bilirubin concentrations, genetically predicted bilirubin using this genotype, and a wide range of health outcomes in a large cohort.Design Cohort ...
Willie Hamilton +3 more
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Impact of Functional Disability on Quality of Life in Patients with Haemophilia: An Observational Study [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Haemophilia is a disease characterised by multiple episodes of spontaneous as well as traumatic bleeding leading to joint pains, joint damage.
Ashish Kavi +3 more
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Metabolism Open, 2021 Objective: Accumulating clinical evidence indicates an inverse relationship between oxidative stress and unconjugated hyperbilirubinemia. This study aimed to compare the prevalence of diabetes microvascular complications in patients with Gilbert syndrome
Ana Cecilia Uribe-Weichers +3 more
doaj +1 more source
ChAdOx1 nCoV-19 protection against SARS-CoV-2 in rhesus macaque and ferret challenge models
Communications Biology, 2021 Lambe, Spencer, Thomas, Gilbert and colleagues report on the detailed immune profile of rhesus macaques and ferrets vaccinated against SARS-CoV-2 under high dose challenge.
Teresa Lambe +43 more
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EDIS, 2018 Ratoon stunting is a major disease of sugarcane that can cause significant yield losses. It is caused by the bacterium Leifsonia xyli subsp. xyli. This pathogen is mainly spread by infected stalk cuttings and contaminated harvesting knives.
Philippe Rott +4 more
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Clinical case of combined genetic pathology in a patient
Терапевтический архив, 2020 Family hypercholesterolemia (HSX) is a form of genetically deterministic increase in blood lipid levels associated with a high risk of cardiovascular disease, usually at a young age. HSX is a common genetic disease found in the general population in most
E. A. Losik +5 more
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Frontiers in Veterinary Science, 2021 Antigenic differences between bovine viral diarrhea virus (BVDV) vaccine strains and field isolates can lead to reduced vaccine efficacy. Historically, antigenic differences among BVDV strains were evaluated using techniques based on polyclonal and ...
Shollie M. Falkenberg +5 more
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