Results 171 to 180 of about 5,285,476 (282)

Conditioning for acute myeloid leukemia: looking beyond intensity. [PDF]

Haematologica
Gilbert JS, Milano F.
europepmc   +1 more source

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

Advanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami, Sanad M. El‐Khatib, Suhas Sureshchandra, Elise Nguyen, Janaki Manoja Vinnakota, Robert Zeiser, Shivashankar Othy, Munjal M. Acharya   +7 more
wiley   +1 more source

Phenotypic features of paroxysmal dyskinesia in Dachshund dogs: 62 cases (2017-2025). [PDF]

J Vet Intern Med
Boyd B, Corsini G, Polidoro D, Bhatti SFM, Grapes N, Alza D, Motta L, Formoso S, De Decker S, Bertram S, Gilbert S, Karpozilou A, Douralidou D, Santifort K, De Frias JM, Bongers J, Kaczmarska A, Liatis T.   +17 more
europepmc   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

Advanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi, Guangying Li, Qian Yang, Rusun Liu, Linghan Gu, Mingmei Wang, John L. Waddington, Fuhai Ji, Xuechu Zhen   +8 more
wiley   +1 more source

Complementary use of 3-dimensional intracardiac echocardiography during complex tricuspid transcatheter edge-to-edge repair. [PDF]

Ann Cardiothorac Surg
Subramaniam V, Onishi T, Tang GHL, Safi LM.   +3 more
europepmc   +1 more source

Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma

Advanced Science, EarlyView.
Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul, Alexandra Moreno Mitchell, Dean O'Neil, Yutong Luo, Khuloud T. Al‐Jamal   +4 more
wiley   +1 more source

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

A systematic review of heterogeneity in clinical trial design for anal cancer radiotherapy-immunotherapy combinations. [PDF]

Clin Transl Radiat Oncol
Samuel RJ, Samson A, Gilbert DC, Adams R, Renehan A, Cook N, Sebag-Montefiore D, Brown S.   +7 more
europepmc   +1 more source

CONSTITUTIONAL HEPATIC DYSFUNCTION (GILBERTS DISEASE)

Medicine, 1959
W T, FOULK, H R, BUTT, C A, OWEN, F F, WHITCOMB, H L, MASON   +4 more
openaire   +2 more sources

Transport–Reaction–Signal Coupling in Lateral Flow Assays for Next‐Generation Point‐of‐Care Diagnostics

Advanced Science, EarlyView.
Lateral flow assays are evolving into interdisciplinary, system‐level sensing platforms. Recent innovations are deconstructed through coupled phases of mass transfer, reaction, and signal transduction, revealing interdependence across porous materials, interfacial chemistry, nanolabels, readout devices, and data‐enabled analysis.
Yan Pan, Yuewei Li, Chao Mi, Zhengwen Yang, Lana McClements, Steven J. Langford, Jiayan Liao   +6 more
wiley   +1 more source