Results 91 to 100 of about 13,120 (243)

10-Gingerol Inhibits Ovarian Cancer Cell Growth by Inducing G2 Arrest [PDF]

Advanced Pharmaceutical Bulletin, 2019
Purpose: Gingerol homologs found in the rhizomes of ginger plants have the potential to benefit human health, including the prevention and treatment of cancer. This study evaluated the effect of 10-gingerol on ovarian cancer cell (HEY, OVCAR3, and SKOV-3)
Andrea Rasmussen, Kaylee Murphy, David W. Hoskin   +2 more
doaj   +1 more source

Gingerol: extraction methods, health implications, bioavailability and signaling pathways

Sustainable Food Technology
Ginger (Zingiber officinale L. Z.o.) is a well-known spice that has been used for centuries as a food ingredient and in traditional medicine.
M. K. Samota, Mandeep Rawat, Manpreet Kaur, Diksha Garg   +3 more
semanticscholar   +1 more source

Inhibition of Prostaglandin and Leukotriene Biosynthesis by Gingerols and Diarylheptanoids.

Chemical and Pharmaceutical Bulletin, 1992
The rhizomes of Zingiber officinale (ginger) and Alpinia officinarum contain potent inhibitors against prostaglandin biosynthesizing enzyme (PG synthetase). Gingerols and diarylhepatanoids were identified as active compounds. Their possible mechanism of action which was deduced from the structures of active compounds indicated that the inhibitors would
KIUCHI, Fumiyuki, IWAKAMI, Satoshi, SHIBUYA, Masaaki, HANAOKA, Fumio, SANKAWA, Ushio   +4 more
openaire   +3 more sources

Development of HPLC method for the determination of 6-gingerol, capsaicin, 8-gingerol, 6-shogaol and 10 gingerol in Zingiber officinale samples [PDF]

, 2015
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Analytical Chemistry Candidate: Martina Urbanová Supervisor: PharmDr. Lucie Havlíková, Ph.D.
Urbanová, Martina
core  

Gingerol sensitizes TRAIL-induced apoptotic cell death of glioblastoma cells

, 2014
Glioblastoma multiforme (GBM) is the most lethal and aggressive astrocytoma of primary brain tumors in adults. Although there are many clinical trials to induce the cell death of glioblastoma cells, most glioblastoma cells have been reported to be ...
Jung, Chang-Hwa, Yong J. Lee, Kim, Dong-Wook, Dong-Wook Kim, Daeho Park, Park, Daeho, Dae-Hee Lee, Lee, Yong J., Chang-Hwa Jung, Lee, Dae-Hee   +9 more
core   +1 more source

Genomic variation drives plant flavor diversification

Journal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu, Yanwei Hao, Yiwei Zhou, Xia Zhang, Rui Xia, Pan Liao   +5 more
wiley   +1 more source

Screening of Active Substances Regulating Alzheimer’s Disease in Ginger and Visualization of the Effectiveness on 6-Gingerol Pathway Targets

Foods
Ginger has been reported to potentially treat Alzheimer’s disease (AD), but the specific compounds responsible for this biological function and their mechanisms are still unknown.
Yecan Pan, Zishu Li, Xiaoyu Zhao, Yang Du, Lin Zhang, Yushun Lu, Ling-Ling Yang, Yilin Cao, Jing Qiu, Yongzhong Qian   +9 more
semanticscholar   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Antiplatelet Effect of Gingerol Isolated from Zingiber officinale

, 1995
The purpose of this investigation was to determine the antiplatelet mechanism of gingerol. Gingerol concentration-dependently (0·5–20 μm) inhibited the aggregation and release reaction of rabbit washed platelets induced by arachidonic acid
Feng-Nien Ko, Jih-Hwa Guh, Ting-Ting Jong, Che-Ming Teng   +3 more
core   +1 more source

Oral Ulcerations and Phytotherapy: Potential Role of Helichrysum Essential Oil—A Literature Review

Oral Diseases, EarlyView.
ABSTRACT Background Recurrent aphthous stomatitis (RAS) is a common yet therapeutically challenging chronic inflammatory disease of the oral mucosa, characterized by recurrent, painful ulcerations that substantially affect patients' quality of life. Objective This review summarizes current evidence on phytotherapy in RAS, with particular focus on the ...
Ruzica Ivkovic, Reka Antic, Avisek Majumder, Suravi Majumder, Dragana Stanisic   +4 more
wiley   +1 more source