Results 191 to 200 of about 13,120 (243)

High-performance liquid chromatographic analysis of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol in ginger-containing dietary supplements, spices, teas, and beverages

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2007
Ginger root powder is widely used as a dietary supplement as well as a spice and flavoring agent in foods and beverages. In this study, we developed a high-performance liquid chromatographic (HPLC) method that is suitable for the analysis of 6-gingerol, 6-shogaol, 8-gingerol, and 10-gingerol in a wide variety of ginger-containing dietary supplements ...
Harvey A Schwertner
exaly   +3 more sources

Polypharmacology and Neuroprotective Effects of Gingerol in Alzheimer’s Disease

Molecular Neurobiology
Alzheimer's disease (AD) is a neurodegenerative condition that results in brain shrinkage and the death of brain cells. The search for new treatment agents with many targets is now crucial due to the insufficient effectiveness, and adverse effects, including pharmacokinetic issues of traditional AD medications. Although phytochemicals have anti-disease
S. Priyadarshini, Keshav Goyal, R. R., Saurabh Gupta, A. Roy, Ritabrata Biswas, Sandeep Patra, Payal Chauhan, Karan Wadhwa, Govind Singh, Mehnaz Kamal, Danish Iqbal, Mohammed Alsaweed, Mohana Vamsi Nuli, M. Abomughaid, Abdulmajeed G. Almutary, J. Sinha, Pooja Bansal, B. Rani, Chakshu Walia, G. Sivaprasad, S. Ojha, V. K. Nelson, N. Jha   +23 more
semanticscholar   +3 more sources

Analgesic and anti-inflammatory activities of [6]-gingerol

Journal of Ethnopharmacology, 2005
In the present study, the analgesic and anti-inflammatory effects of [6]-gingerol, which is the pungent constituent of ginger, were performed. Intraperitoneal administration of [6]-gingerol (25 mg/kg-50 mg/kg) produced an inhibition of acetic acid-induced writhing response and formalin-induced licking time in the late phase.
Hao Yuan Cheng, Wen-Huang Peng, Jung-Chun Liao   +2 more
exaly   +3 more sources

A comprehensive review on Ginger (Zingiber officinale) as a potential source of nutraceuticals for food formulations: Towards the polishing of gingerol and other present biomolecules.

Food Chemistry, 2023
Currently, ginger is one the most consumed plants when dealing with the treatments of various illnesses. So far, it is known that various biologically active molecules, such as gingerols, shogaols and zingerone, among others, are the main responsible for
Clarissa Garza-Cadena, Daniela Marian Ortega-Rivera, Gerson Machorro-García, Eloy Mauricio Gonzalez-Zermeño, Diego Homma-Dueñas, Maksymilian Plata-Gryl, R. Castro-Muñoz   +6 more
semanticscholar   +1 more source

Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol

Journal of Ethnopharmacology, 2010
Zingiber officinale Rosc. (Zingiberaceae) has been traditionally used in Ayurvedic, Chinese and Tibb-Unani herbal medicines for the treatment of various illnesses that involve inflammation and which are caused by oxidative stress. Although gingerols and shogaols are the major bioactive compounds present in Zingiber officinale, their molecular ...
Swarnalatha, Dugasani, Mallikarjuna Rao, Pichika, Vishna Devi, Nadarajah, Madhu Katyayani, Balijepalli, Satyanarayana, Tandra, Jayaveera Narsimha, Korlakunta   +5 more
openaire   +2 more sources

Antihepatotoxic actions of gingerols and diarylheptanoids

Journal of Ethnopharmacology, 1985
The antihepatotoxic effects of gingerols, shogaols, diarylheptanoids and related analogues were assessed utilizing carbon tetrachloride- and galactosamine-induced cytotoxicity in primary cultured rat hepatocytes. Most congeners exhibited significant actions in these assay methods.
H, Hikino, Y, Kiso, N, Kato, Y, Hamada, T, Shioiri, R, Aiyama, H, Itokawa, F, Kiuchi, U, Sankawa   +8 more
openaire   +2 more sources

Pharmacokinetics of Gingerols, Shogaols, and Their Metabolites in Asthma Patients

Journal of Agricultural and Food Chemistry, 2022
6-Gingerol and 6-shogaol are the most abundant gingerols and shogaols in ginger root and have been shown to reduce the asthmatic phenotype in murine models of asthma. Several studies have described the pharmacokinetics of gingerols and shogaols in humans following the oral ingestion of ginger, while little was known about the metabolism of these ...
Shuwei Zhang, Emily DiMango, Yingdong Zhu, Tarnjot K. Saroya, Charles W. Emala, Shengmin Sang   +5 more
openaire   +2 more sources

Synthesis of gingerol and diarylheptanoids

Tetrahedron: Asymmetry, 2011
Abstract The synthesis of gingerol 1 and related compounds 2 – 5 along with diarylheptanoids 6 – 8 has been accomplished using a Keck allylation, Crimmins’ aldol reaction, aldehyde coupling with acetylene, and chelation controlled reductions as the key reactions.
Gowravaram Sabitha, Chitti Srinivas, Teega Rammohan Reddy, Kurra Yadagiri, Jhillu Singh Yadav   +4 more
openaire   +1 more source

Microsomal Hydroxylation and Glucuronidation of [6]-Gingerol

Journal of Agricultural and Food Chemistry, 2006
[6]-Gingerol is the major pungent principle of ginger and frequently is ingested with various condiments and nutritional supplements. We report here that incubation of [6]-gingerol with NADPH-fortified rat hepatic microsomes gave rise to eight metabolites, which were tentatively identified by GC-MS analysis as two products of aromatic hydroxylation as ...
Pfeiffer, E., Heuschmid, F. F., Kranz, S., Metzler, M.   +3 more
openaire   +2 more sources

6-Gingerol contents of several ginger varieties of Northeast India and correlation of their antioxidant activity in respect to phenolics and flavonoids contents.

Phytochemical Analysis, 2023
INTRODUCTION Ginger constitutes the rhizome part of the plant Zingiber officinale from the Zingiberaceae family. A large number of ginger varieties with high sensorial and functional quality are found in Northeast India.
Suparna Ghosh, Bhaskar Das, P. Haldar, A. Kar, S. Chaudhary, Keithellakpam Ojit Singh, P. Bhardwaj, Nanaocha Sharma, P. Mukherjee   +8 more
semanticscholar   +1 more source