Results 31 to 40 of about 479 (109)

Porphyromonas gingivalis and Treponema denticola Mixed Microbial Infection in a Rat Model of Periodontal Disease

open access: yesInterdisciplinary Perspectives on Infectious Diseases, Volume 2010, Issue 1, 2010., 2010
Porphyromonas gingivalis and Treponema denticola are periodontal pathogens that express virulence factors associated with the pathogenesis of periodontitis. In this paper we tested the hypothesis that P. gingivalis and T. denticola are synergistic in terms of virulence; using a model of mixed microbial infection in rats.
Raj K. Verma   +10 more
wiley   +1 more source

Enteric bacterial proteases in inflammatory bowel disease- pathophysiology and clinical implications [PDF]

open access: yes, 2013
Numerous reports have identified a dysbiosis in the intestinal microbiota in patients suffering from inflammatory bowel diseases (IBD), yet the mechanism(s) in which this complex microbial community initiates or perpetuates inflammation remains unclear ...
Carroll, Ian M., Maharshak, Nitsan
core   +2 more sources

Oral SARS‐CoV‐2 Infection and Risk for Long Covid

open access: yesReviews in Medical Virology, Volume 35, Issue 2, March 2025.
ABSTRACT SARS‐CoV‐2 is an oral pathogen that infects and replicates in mucosal and salivary epithelial cells, contributing to oral post‐acute sequelae COVID‐19 (PASC) and other oral and non‐oral pathologies. While pre‐existing inflammatory oral diseases provides a conducive environment for the virus, acute infection and persistence of SARS‐CoV‐2 can ...
Joel Schwartz   +5 more
wiley   +1 more source

Identification of a new subtype of dipeptidyl peptidase 11 and a third group of the S46-family members specifically present in the genus Bacteroides [PDF]

open access: yes, 2018
Peptidase family S46 consists of two types of dipeptidyl-peptidases (DPPs), DPP7 and DPP11, which liberate dipeptides from the N-termini of polypeptides along with the penultimate hydrophobic and acidic residues, respectively.
Bezerra Gustavo Arruda   +5 more
core   +2 more sources

HPV-related and unrelated oropharyngeal cancer : Contribution of oral pathobionts Treponema denticola and Porphyromonas gingivalis to carcinogenesis [PDF]

open access: yes, 2023
The incidence of oropharyngeal squamous cell carcinoma (OPSCC) associated with human papillomavirus (HPV) has increased in western countries in the last decades, whereas the number of HPV unrelated OPSCC cases has remained stable or even declined.
Kylmä, Anna Kaisa
core  

Non‐canonical amino acid bioincorporation into antimicrobial peptides and its challenges

open access: yesJournal of Peptide Science, Volume 30, Issue 6, June 2024.
Bioincorporation of non‐canonical amino acids (ncAAs) as a method of integration into antimicrobial peptides (AMPs) is an emerging field geared towards developing solid‐phase synthesis as a green, cheaper, and scalable alternative for commercialisation of AMPs.
George Nkrumah Enninful   +4 more
wiley   +1 more source

Ecological, beneficial, and pathogenic functions of the Type 9 Secretion System

open access: yesMicrobial Biotechnology, Volume 17, Issue 6, June 2024.
This mini review delves into the broad spectrum of proteins secreted by the bacterial type 9 secretion system (T9SS). It focuses on the roles of T9SS‐secreted proteins in pathogenesis, bacterial interactions, host colonization, and the maintenance of ecosystem health.
Sofia T. Rocha   +2 more
wiley   +1 more source

SARS‐CoV‐2, periodontal pathogens, and host factors: The trinity of oral post‐acute sequelae of COVID‐19

open access: yesReviews in Medical Virology, Volume 34, Issue 3, May 2024.
Abstract COVID‐19 as a pan‐epidemic is waning but there it is imperative to understand virus interaction with oral tissues and oral inflammatory diseases. We review periodontal disease (PD), a common inflammatory oral disease, as a driver of COVID‐19 and oral post‐acute‐sequelae conditions (PASC). Oral PASC identifies with PD, loss of teeth, dysgeusia,
Joel Schwartz   +4 more
wiley   +1 more source

Development of low-cost and portable detection platforms for bacterial detection [PDF]

open access: yes, 2022
In this study, a diagnostic platform for detecting pathogens, including Listeria monocytogenes, E. coli O157:H11, Staphylococcus aureus, Legionella spp., P. gingivalis, and Pseudomonas aeruginosa, has been developed. Fluorogenic substrates were used as a
Alhogail, Sahar
core  

Modes of inhibition of cysteine proteases [PDF]

open access: yes, 2004
Cysteine proteases are involved in many physiological processes and their hyperactivity may lead to severe diseases. Nature has developed various strategies to protect cells and whole organisms against undesired proteolysis. One of them is the control of
Chmiel, Dorota   +2 more
core  

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