Results 21 to 30 of about 116 (84)
Journal of Periodontal Research, EarlyView.This graphical abstract illustrates the role of matrix metalloproteinases (MMPs) across the pathogenesis, diagnosis, and therapeutics of periodontal and peri‐implant diseases. Microbial and host stimuli trigger MMP activation leading to extracellular matrix breakdown, point‐of‐care aMMP‐8 detection aids diagnosis, and adjunctive or AI‐assisted ...
Timo Sorsa +5 more
wiley +1 more source
Interdisciplinary Perspectives on Infectious Diseases, Volume 2010, Issue 1, 2010., 2010 Porphyromonas gingivalis and Treponema denticola are periodontal pathogens that express virulence factors associated with the pathogenesis of periodontitis. In this paper we tested the hypothesis that P. gingivalis and T. denticola are synergistic in terms of virulence; using a model of mixed microbial infection in rats.
Raj K. Verma +10 more
wiley +1 more source
Enteric bacterial proteases in inflammatory bowel disease- pathophysiology and clinical implications [PDF]
, 2013 Numerous reports have identified a dysbiosis in the intestinal microbiota in patients suffering from inflammatory bowel diseases (IBD), yet the mechanism(s) in which this complex microbial community initiates or perpetuates inflammation remains unclear ...
Carroll, Ian M., Maharshak, Nitsan
core +2 more sources
Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications
Journal of Periodontal Research, EarlyView.Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu +4 more
wiley +1 more source
Journal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron +3 more
wiley +1 more source
HPV-related and unrelated oropharyngeal cancer : Contribution of oral pathobionts Treponema denticola and Porphyromonas gingivalis to carcinogenesis [PDF]
, 2023 The incidence of oropharyngeal squamous cell carcinoma (OPSCC) associated with human papillomavirus (HPV) has increased in western countries in the last decades, whereas the number of HPV unrelated OPSCC cases has remained stable or even declined.
Kylmä, Anna Kaisa
core
Oral SARS‐CoV‐2 Infection and Risk for Long Covid
Reviews in Medical Virology, Volume 35, Issue 2, March 2025.ABSTRACT SARS‐CoV‐2 is an oral pathogen that infects and replicates in mucosal and salivary epithelial cells, contributing to oral post‐acute sequelae COVID‐19 (PASC) and other oral and non‐oral pathologies. While pre‐existing inflammatory oral diseases provides a conducive environment for the virus, acute infection and persistence of SARS‐CoV‐2 can ...
Joel Schwartz +5 more
wiley +1 more source
Development of low-cost and portable detection platforms for bacterial detection [PDF]
, 2022 In this study, a diagnostic platform for detecting pathogens, including Listeria monocytogenes, E. coli O157:H11, Staphylococcus aureus, Legionella spp., P. gingivalis, and Pseudomonas aeruginosa, has been developed. Fluorogenic substrates were used as a
Alhogail, Sahar
core
Insights Into the Mechanism of Action of Chlorhexidine on Porphyromonas gingivalis
International Journal of Dentistry, Volume 2025, Issue 1, 2025.Chlorhexidine (CHX) remains the most effective antiseptic in periodontal therapy, multiple reports have identified ultrastructural antibacterial effects of CHX on oral bacteria, however, little is known about its molecular mechanism of action on Porphyromonas gingivalis, an important pathobiont directly associated with the pathogenesis of periodontitis.
Karen Mejía +3 more
wiley +1 more source
Non‐canonical amino acid bioincorporation into antimicrobial peptides and its challenges
Journal of Peptide Science, Volume 30, Issue 6, June 2024.Bioincorporation of non‐canonical amino acids (ncAAs) as a method of integration into antimicrobial peptides (AMPs) is an emerging field geared towards developing solid‐phase synthesis as a green, cheaper, and scalable alternative for commercialisation of AMPs.
George Nkrumah Enninful +4 more
wiley +1 more source