Bacterial protease uses distinct thermodynamic signatures for substrate recognition. [PDF]
, 2017 Porphyromonas gingivalis and Porphyromonas endodontalis are important bacteria related to periodontitis, the most common chronic inflammatory disease in humans worldwide.
Bezerra, GA +8 more
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Porphyromonas gingivalis gingipains induce a pro-inflammatory extracellular microenvironment : the role of PAR-2 and fibronectin. [PDF]
, 2016 Periodontitis is a chronic inflammatory disease that is characterized by severe tissue destruction of the gingiva and other tooth supporting structures; if left untreated, tooth loss and disintegration of the alveolar bone occurs.
Marschall, Jeffrey S.
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Porphyromonas gingivalis peptidylarginine deiminase in the aetiology of rheumatoid arthritis [PDF]
, 2017 Anti-citrullinated protein antibodies (ACPA) are the main autoantibodies in rheumatoid arthritis (RA). Citrullination is the conversion of arginine to citrulline by peptidylarginine deiminase (PAD) enzymes. Periodontitis (PD) is a risk factor for RA, and
Montgomery, Anna B
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The Responses of Human Neutrophils to Tobacco Smoke Components [PDF]
, 2012 Indiana University-Purdue University Indianapolis (IUPUI)Tobacco smoking is considered a major modifiable risk factor for periodontal disease. Tobacco contains about 6700 compounds and almost 4000 compounds of these have been identified in tobacco smoke.
Al-Shibani, Nouf Khider
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Interactions of porphyromonas gingivalis with bone marrow cells: implications on mediators of bone resorption [PDF]
, 2012 PhDPeriodontitis is a multi-factorial disease characterised by the loss of connective tissue and underlying alveolar bone leading to the loss of teeth. Porphyromonas gingivalis (P.
Reddi, Durga
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Porphyromonas gingivalis gingipains cause defective macrophage migration towards apoptotic cells and inhibit phagocytosis of primary apoptotic neutrophils [PDF]
Resolution of inflammation involves suppression of inflammatory cell infiltration, effective clearance of apoptotic cells and induction of an anti-inflammatory response thereby re-establishing tissue homeostasis.
Ajay Castro, Sowmya
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Role of Porphyromonas gingivalis Gingipains in Caspase-1 Activation and Phagocytosis of Tannerella forsythia [PDF]
, 2016 학위논문 (박사)-- 서울대학교 대학원 : 치의학대학원 치의과학과 분자미생물치의학전공, 2016. 2. 최봉규.Objectives In the pathogenesis of periodontitis, Porphyromonas gingivalis plays a role as a keystone pathogen that dysregulates host immune responses and results in dysbiosis in oral microbial
정영정
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Modulation de la réponse inflammatoire de l'hôte par les bactéries parodontopathogènes : mécanisme de pathogénicité et cible thérapeutique potentielle [PDF]
, 2007 Tableau d'honneur de la Faculté des études supérieures et postdoctorales, 2006 ...
Bodet, Charles
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An in silico analysis, purification and partial kinetic characterisation of a serine protease from Gelidium pristoides [PDF]
, 2020 The aim of this study was to characterize the protease enzyme (s) from red algae. An in silico analysis of red algae genomes was used to identify gene coding for protease.
Ntsata, Zolani
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Interleukin-1[Alpha] production in periodontal disease: the interaction of bacteria and gene polymorphisms. [PDF]
, 2007 PhDThere is good evidence that interleukin-I alpha (IL-Ia) plays a key role in both the host response to bacteria and the tissue destruction associated with periodontal disease.
Bostanci, Nagihan
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