Results 51 to 60 of about 47,748 (293)

Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond

Advanced Science, EarlyView.
Dental stem cell (DSC) aging involves genomic instability, mitochondrial dysfunction, telomere attrition, and epigenetic alterations, leading to impaired proliferation, reduced differentiation potential, and pro‐inflammatory secretory activity. These processes drive cellular senescence and compromise regenerative and immunomodulatory functions, thereby
Xinyuan Zhao, Yunfan Lin, Pei Lin, Ye Lu, Jiarong Zheng, Xu Chen, Zihao Zhou, Li Cui   +7 more
wiley   +1 more source

LPS‐Induced Mitochondrial Damage via SLC41A1‐Mediated Magnesium Ion Efflux Leads to the Pyroptosis of Dental Stem Cells

Advanced Science, EarlyView.
Lipopolysaccharide induces upregulation of the magnesium (Mg2+) efflux transporter solute carrier family 41 member 1 in dental stem cells, leading to a decrease in intracellular Mg2+ concentration and promoting the binding of oligomycin sensitivity‐conferring protein and cyclophilinD.
Yuan Liu, Chenyu Song, Liyuan Zhang, Xue Han, Chaoyuan Li, Yanhong Yan, Ludan Xing, Mengting Si, Bo Yang, Lingyuan Cheng, Akimi Muramatsu, Beizhan Jiang   +11 more
wiley   +1 more source

Prevalence of dental caries, gingival disease, and periodontal disease in Bihar population: A community-based research

SRM Journal of Research in Dental Sciences, 2020
Objective: The objective of this study was to assess the prevalence of dental caries, gingival diseases, and periodontal disease among the rural population of Bihar, India.
Amit Kumar Singh, Rashi Chauhan, Khushboo Rani, Kriti Singh, Kumar Anand, Wagisha Barbie   +5 more
doaj   +1 more source

Blockade of cyclophilin D rescues dexamethasone-induced oxidative stress in gingival tissue. [PDF]

PLoS ONE, 2017
Glucocorticoids (GCs) are frequently used for the suppression of inflammation in chronic inflammatory diseases. Excessive GCs usage is greatly associated with several side effects, including gingival ulceration, the downward migration of the epithelium ...
Yuting He, Ling Zhang, Zhuoli Zhu, Anqi Xiao, Haiyang Yu, Xueqi Gan   +5 more
doaj   +1 more source

Smart Gated Hollow Mesoporous Silica Hydrogel for Targeting Endoplasmic Reticulum Stress and Promoting Periodontal Tissue Regeneration

Advanced Science, EarlyView.
The hollow mesoporous silica loaded with quercetin (HM‐QU@PEG) is combined with a thermosensitive anti‐bacterial matrix (TF127) to prepare HQUP@TF127. HQUP@TF127 effectively eliminates excessive ROS, alleviates endoplasmic reticulum stress, relieves mitochondrial calcium overload, and blocks the p53‐dependent apoptotic cascade. Furthermore, it enhances
Guichun Wang, Yuxiao Wang, Yang Ding, Xiang Chen, Shuhan Li, Wenqi Zhou, Rui Ma, Maomao Tang, Xinyuan Shao, Zixuan Shu, Ning He, Xiaodong Ma, Jian Guo, Chengjun Peng, Shuangying Gui   +14 more
wiley   +1 more source

Prevalence of gingival recession in dentistry students (2017-2018)

مجله دانشگاه علوم پزشکی گرگان, 2019
Background and Objective: Gingival recession is a common disease leads to esthetic problems, increased sensitivity of teeth and root caries. This study was done to determine the prevalence of gingival recession in dental students with high level of oral ...
Fahimeh Mirzaali, Amirreza Ahmadinia, Gholamreza Roshandel   +2 more
doaj  

Interfacial Coordination‐Engineered Emulgel Modulates the Osteo‐Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway‐Induced Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of HIPPE‐QU‐mediated periodontal regeneration. a) Fabrication process and microstructure of HIPPE‐QU. b) Antimicrobial and immunomodulatory HIPPE‐QU hydrogel for periodontal regeneration. HIPPE‐QU hydrogel co‐delivers HA‐Cu, GNPs, and QU, providing antimicrobial effects and reprogramming the immune microenvironment to promote ...
Hui Zhang, Xiao Huang, Rui Chen, Weimin Lin, Linke Li, Xi Peng, Xinxi Yang, Xingyu Chen, Tailin Guo, Jie Weng, Jianshu Li, Quan Yuan, Huan Tan, Mengyuan Wang   +13 more
wiley   +1 more source

Periodontal Inflammation: From Gingivitis to Systemic Disease? [PDF]

, 2011
There has been a resurgence of interest in recent years in the systemic effects of oral infections such as periodontal diseases. The study of the various means by which periodontal infections and inflammation may influence a variety of systemic conditions is collectively referred to as periodontal medicine.
Panagakos, Fotinos, Scannapieco, Frank
openaire   +4 more sources

All‐In‐One Iontronic Sensing Aligner for High‐Precision 3D Orthodontic Force Monitoring

Advanced Science, EarlyView.
A wireless, battery‐free orthodontic sensing system is developed by integrating a cross‐shaped iontronic sensor and an origami‐inspired NFC circuit into clear aligners. This all‐in‐one device enables real‐time, in vivo 3D force monitoring with high precision and long‐term stability, providing clinicians with quantitative biomechanical feedback to ...
Jiahao Guo, Qin Niu, Jilei Xu, Liyan Wang, Xiangyang Wang, Jiangdong Gong, Hanfei Zhu, Ruojiang Wang, Yu Chang, Tingrui Pan, Si Chen   +10 more
wiley   +1 more source

Fimbriae‐Targeted Peptide‐Selenoviologen Cyclophane Complex for Enhanced Photodynamic Therapy of Periodontitis

Aggregate, EarlyView.
This study develops a supramolecular photosensitizer (SeVB⊃PQ) by combining SeVB with a P. gingivalis‐targeting peptide. SeVB⊃PQ selectively binds P. gingivalis, boosts ROS generation under irradiation, disrupts ATP synthesis, restores microbial balance, reduces inflammation, and promotes alveolar bone regeneration, offering a promising platform for ...
Rui Ding, Yawen Li, Yuchen Zhang, Qi Sun, Ang Li, Kun Zhou, Dandan Pei, Gang He   +7 more
wiley   +1 more source