Gingival Overgrowth in an Adult Male Patient. [PDF]
Cureus, 2022 Pyogenic granuloma (PG) is an oral reactive inflammatory hyperplasia of connective tissue that can occur in response to hormonal changes and local irritation such as calculus, fractured teeth, rough dental restorations, and foreign materials. It is nonneoplastic and predominant in the second decade of life in young adult females.
Mahajan R, Alawi F, France K.
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Drug Induced Gingival Overgrowth: A Rare Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2015 Gingival overgrowth is well documented side effect associated with three major classes of drugs viz, anticonvulsants, calcium channel blockers, and immunosuppressants. Despite our greater understanding of pathogenesis of Drug induced Gingival Overgrowth
Setu Mathur +4 more
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Quantification of matrix metalloproteinases MMP-8 and MMP-9 in gingival overgrowth [PDF]
Saudi Dental Journal, 2021 Background: Matrix metalloproteinases (MMPs) are proteolytic enzymes involved in extracellular matrix remodeling of all body tissues, including oral tissues such as gingival tissue. Expression levels of MMPs are widely studied as important biomarkers for
Jennifer Orozco-Páez +3 more
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Marked Gingival Overgrowth Protruding from the Oral Cavity Due to Sodium Valproate [PDF]
DiagnosticsDrug-induced gingival overgrowth is associated with various systemic diseases, including epilepsy. Among antiepileptic medications, phenytoin is commonly reported to cause this condition.
Mami Uegami +2 more
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Initial periodontal therapy for seven patients with aplastic anemia and drug-induced gingival overgrowth: a case series report [PDF]
BMC Oral HealthBackground Patients with aplastic anemia are at increased risk of bleeding, which often limits conventional periodontal treatment. Although drug-induced gingival overgrowth is well-documented, its management in this high-risk population has not been ...
Xinxin Lv +6 more
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Gingival overgrowth in fixed orthodontic therapy. [PDF]
Rom J Morphol EmbryolThe oral mucosa can suffer a series of traumatic injuries from various causes (bacterial plaque, tartar, fillings, incorrectly adapted prosthesis). A risk factor generating periodontal diseases is represented by fixed orthodontic therapy, if the forces exerted on it are excessive.
Rădeanu AC +5 more
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Phenytoin- and amlodipine-induced gingival overgrowth
Journal of Dental Sciences, 2012 Drug-induced gingival overgrowth is an adverse event associated with three types of drugs, i.e., anticonvulsants, immunosuppressants, and calcium-channel blockers.
Ching-Wen Chang +2 more
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The Possible Potential Therapeutic Targets for Drug Induced Gingival Overgrowth [PDF]
Mediators of Inflammation, 2013 Gingival overgrowth is a side effect of certain medications. The most fibrotic drug-induced lesions develop in response to therapy with phenytoin, the least fibrotic lesions are caused by cyclosporin A, and the intermediate fibrosis occurs in nifedipine ...
Tamilselvan Subramani +2 more
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Transcriptional Analysis Reveals Key Genes in the Pathogenesis of Nifedipine-Induced Gingival Overgrowth [PDF]
Analytical Cellular Pathology, 2020 Background. Nifedipine-induced gingival overgrowth (NGO) is a multifactorial pathogenesis with increased extracellular matrix including collagen and glycans, inflammatory cytokines, and phenotype changes of fibroblasts. However, the molecular etiology of
Yanqin Ju +3 more
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Cyclosporine A Causes Gingival Overgrowth by Promoting Entry into the S Phase at the G1/S Cell Cycle Checkpoint in Gingival Fibroblasts Exposed to Lipopolysaccharide [PDF]
DiseasesObjectives: Cyclosporine A promotes gingival fibrosis by enhancing the proliferation of gingival fibroblasts, leading to gingival overgrowth. The population of gingival fibroblasts is regulated by cell cycle machinery, which balances cell growth and ...
Reiri Takeuchi +11 more
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