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Acta stomatologica Naissi, 2015 © 2015 Faculty of Medicine in Niš. Clinic of Dentistry in Niš. All rights reserved. Gingival health is a prerequisite for the health of the whole body. Severe gingival overgrowth affects speech, mastication, and nutrition, causes aesthetic concerns and increases susceptibility to periodontitits and systemic diseases.
Ivana Timotijević +7 more
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Apoptosis in Gingival Overgrowth Tissues [PDF]
Journal of Dental Research, 2007 Variations in the balance between cell proliferation and apoptosis could contribute to the etiology of gingival overgrowth. The aim of this study was to test the hypothesis that, in fibrotic gingival lesions, fibroblast proliferation is stimulated and apoptosis is decreased.
Kantarci, Alpdoǧan I +6 more
openaire +5 more sources
Phenytoin- and amlodipine-induced gingival overgrowth
Journal of Dental Sciences, 2012 Drug-induced gingival overgrowth is an adverse event associated with three types of drugs, i.e., anticonvulsants, immunosuppressants, and calcium-channel blockers.
Ching-Wen Chang +2 more
doaj +2 more sources
Can chlorhexidine mouthwash twice daily ameliorate cyclosporine-induced gingival overgrowth?
Journal of the Formosan Medical Association, 2013 Gingival overgrowth can be induced in patients treated with cyclosporine-A (CsA), an immunosuppressant often used following organ transplantation. A pre-existing rat model designed to mimic CsA-induced gingival overgrowth in humans was used to test the ...
Ching-Hwa Gau +5 more
doaj +2 more sources
Upregulation of lysyl oxidase expression in cyclosporin A-induced gingival overgrowth
Journal of Dental Sciences, 2009 Lysyl oxidase (LOX) is involved in the initial steps of converting soluble monomers of collagen and elastin into insoluble fibers in the extracellular matrix. LOX was found to be upregulated in some fibrotic diseases.
Chung-Hung Tsai +2 more
doaj +2 more sources
Incidence of amlodipine-induced gingival overgrowth in the rural population of Loni
Journal of Indian Society of Periodontology, 2014 Aims: Since the incidence of gingival overgrowth induced by amlodipine remains poorly defined, this study was carried out with an aim to determine the incidence.
Avneesh Tejnani +6 more
doaj +2 more sources
The Possible Potential Therapeutic Targets for Drug Induced Gingival Overgrowth [PDF]
Mediators of Inflammation, 2013 Gingival overgrowth is a side effect of certain medications. The most fibrotic drug-induced lesions develop in response to therapy with phenytoin, the least fibrotic lesions are caused by cyclosporin A, and the intermediate fibrosis occurs in nifedipine ...
Tamilselvan Subramani +2 more
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Non-Plaque Induced Diffuse Gingival Overgrowth: An Overview [PDF]
Applied Sciences, 2022 Non-plaque induced diffuse gingival overgrowth represents a broad class of conditions caused by several etiological factors. The aim of this review is to highlight the most recent updates and classifications of all the existent gingival overgrowths.
Domenico De Falco +5 more
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Nonsurgical Management of Nifedipine Induced Gingival Overgrowth [PDF]
Case Reports in Dentistry, 2014 Drug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The
George Sam, Staly Chakkalakkal Sebastian
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Head & Face Medicine, 2006 Background Drug-induced gingival overgrowth is a frequent adverse effect associated principally with administration of the immunosuppressive drug cyclosporin A and also certain antiepileptic and antihypertensive drugs.
Özdemir B Handan +3 more
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