Apoptosis in Gingival Overgrowth Tissues [PDF]
Journal of Dental Research, 2007 Variations in the balance between cell proliferation and apoptosis could contribute to the etiology of gingival overgrowth. The aim of this study was to test the hypothesis that, in fibrotic gingival lesions, fibroblast proliferation is stimulated and apoptosis is decreased.
Kantarci, Alpdoǧan I +6 more
openaire +5 more sources
Can chlorhexidine mouthwash twice daily ameliorate cyclosporine-induced gingival overgrowth?
Journal of the Formosan Medical Association, 2013 Gingival overgrowth can be induced in patients treated with cyclosporine-A (CsA), an immunosuppressant often used following organ transplantation. A pre-existing rat model designed to mimic CsA-induced gingival overgrowth in humans was used to test the ...
Ching-Hwa Gau +5 more
doaj +2 more sources
Phenytoin- and amlodipine-induced gingival overgrowth
Journal of Dental Sciences, 2012 Drug-induced gingival overgrowth is an adverse event associated with three types of drugs, i.e., anticonvulsants, immunosuppressants, and calcium-channel blockers.
Ching-Wen Chang +2 more
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The Possible Potential Therapeutic Targets for Drug Induced Gingival Overgrowth [PDF]
Mediators of Inflammation, 2013 Gingival overgrowth is a side effect of certain medications. The most fibrotic drug-induced lesions develop in response to therapy with phenytoin, the least fibrotic lesions are caused by cyclosporin A, and the intermediate fibrosis occurs in nifedipine ...
Tamilselvan Subramani +2 more
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Non-Plaque Induced Diffuse Gingival Overgrowth: An Overview [PDF]
Applied Sciences, 2022 Non-plaque induced diffuse gingival overgrowth represents a broad class of conditions caused by several etiological factors. The aim of this review is to highlight the most recent updates and classifications of all the existent gingival overgrowths.
Domenico De Falco +5 more
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Laser-Assisted Periodontal Management of Drug-Induced Gingival Overgrowth under General Anesthesia: A Viable Option [PDF]
Case Reports in Dentistry, 2013 Gingival overgrowth/hyperplasia can be attributed to several causes, but drug-induced gingival overgrowth/hyperplasia arises secondarily to prolonged use of antihypertensive drugs, anticonvulsants and immunosuppressants.
Tupili Muralikrishna +3 more
doaj +2 more sources
Mechanism of Ciclosporin-induced gingival hyperplasia An in vitro study of the effect of ciclosporin on human gingival fibroblasts and oral keratinocytes [PDF]
, 2011 PhDObjectives: Ciclosporin (CsA) is a potent and effective immuno-suppressive drug, but its use is associated with the development of gingival hyperplasia in up to 70% of patients.
Hanino, Mohammad
core +4 more sources
Comprehensive Management of a Patient with Drug Induced Gingival Overgrowth and Metabolic Syndrome [PDF]
, 2021 Periodontitis and metabolic syndrome demonstrate a bidirectional relationship complicated by multiple risk factors. Gingival overgrowth (GO) is a manifestation of exaggerated inflammatory response of the gingivae in response to biofilm and varying local ...
B M C A Bandaranayake +3 more
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Conflation of gingival overgrowth and schwannoma [PDF]
BMJ Case Reports, 2014 The authors describe a seminal case report of a 10-year-old boy with enlarged gingivae in relation to his maxillary anterior teeth. The lesion, provisionally diagnosed as idiopathic gingival enlargement, was completely excised and divided into two sections.
Parth, Purwar +3 more
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Quantification of matrix metalloproteinases MMP-8 and MMP-9 in gingival overgrowth
Saudi Dental Journal, 2021 Background: Matrix metalloproteinases (MMPs) are proteolytic enzymes involved in extracellular matrix remodeling of all body tissues, including oral tissues such as gingival tissue. Expression levels of MMPs are widely studied as important biomarkers for
Jennifer Orozco-Páez +3 more
doaj +1 more source