Drug-Induced Gingival Overgrowth-Molecular Aspects of Drug Actions. [PDF]
Int J Mol Sci, 2023 Drug-induced gingival overgrowth (DIGO) is one of the side effects produced by therapeutic agents, most commonly phenytoin, nifedipine and cyclosporin A. However, the precise mechanism of DIGO is not entirely understood.
Droździk A, Droździk M.
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Transcriptional Analysis Reveals Key Genes in the Pathogenesis of Nifedipine-Induced Gingival Overgrowth [PDF]
Analytical Cellular Pathology, 2020 Background. Nifedipine-induced gingival overgrowth (NGO) is a multifactorial pathogenesis with increased extracellular matrix including collagen and glycans, inflammatory cytokines, and phenotype changes of fibroblasts. However, the molecular etiology of
Yanqin Ju +3 more
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Calcium Channel Blockers Induced Gingival Overgrowth: A Comprehensive Review from a Dental Perspective. [PDF]
J Int Soc Prev Community Dent, 2022 Background: Gingival overgrowth (GO) as a manifestation of calcium channel blockers (CCBs) was first introduced in the literature by Ramon et al. in 1984.
Damdoum M +3 more
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Bibliometric analysis of research trends and characteristics of drug-induced gingival overgrowth. [PDF]
Front Public Health, 2022 Objectives Drug-induced gingival overgrowth (DIGO) is a frequent adverse medication reaction that is generally caused by cyclosporine, phenytoin, and nifedipine, which belong to the category of immunosuppressants, anticonvulsants, and calcium channel ...
Zhang R, Wu J, Zhu J, Wang X, Song J.
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Drug-induced gingival overgrowth in cardiovascular patients. [PDF]
World J Cardiol, 2021 Drug-induced gingival overgrowth (DIGO) is a pathological growth of gingival tissue, primarily associated with calcium channel blockers and immunosuppressants. Consequently, it is mainly seen in cardiovascular and transplanted patients.
Bajkovec L +3 more
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Er,Cr:YSGG Laser Therapy for Drug-Induced Gingival Overgrowth: A Report of Two Case Series. [PDF]
Front Surg, 2022 Background Drug-induced gingival overgrowth is common but neglected in patients with systemic disease medications until it seriously affects the quality of life.
Liu Y, Peng Q, Liu B, Wang Z, Cao Q.
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Cyclosporine‐induced gingival overgrowth—Review
Dermatologic Therapy, 2022 Drug‐induced gingival overgrowth (DIGO) is an undesirable effect resulting from the therapy of one of the three groups of drugs: phenytoin, calcium channel blockers, and cyclosporine A (CsA).
Joanna Chojnacka-Purpurowicz +3 more
semanticscholar +3 more sources
Management of Aberrant Frenum and Gingival Overgrowth in Orthodontic Patients: A Case Report. [PDF]
CureusThe frenum, a fold of mucous membrane, connects the lip and cheek to the alveolar mucosa, gingiva, and underlying periosteum. When the frenum is positioned excessively near the gingival margin, it has the potential to compromise gingival health, impeding
Gupta A +5 more
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Treatment of calcium channel blocker-induced gingival overgrowth without modifying medication. [PDF]
BMJ Case Rep, 2021 Gingival overgrowth is a common side effect of calcium channel blockers used in the treatment of cardiovascular diseases. While controversial, management includes discontinuing the calcium channel blocker. We report the case of a 66-year-old Japanese man
Morikawa S +3 more
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Conventional Gingivectomy Procedure in the Management of Orthodontic-Induced Gingival Overgrowth: A Case Report. [PDF]
CureusGingival enlargement (GE) can result from gingival inflammation, fibrous overgrowth, or a combination of both factors. Various etiological factors contribute to GE, including low-grade trauma, iatrogenic causes, drug-induced effects, systemic diseases ...
Dalal AM, Oza RR, Shirbhate U, Gurav T.
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