Results 21 to 30 of about 79,732 (230)
Cyclosporine A: Novel concepts in its role in drug-induced gingival overgrowth
Dental Research Journal, 2015 Cyclosporine is a selective immunosuppressant that has a variety of applications in medical practice. Like phenytoin and the calcium channel blockers, the drug is associated with gingival overgrowth.
Deepa Ponnaiyan, Visakan Jegadeesan
doaj +1 more source
Medical Management of Cyclosporine-Induced Gingival Overgrowth Using Oral Azithromycin in Six Dogs
Veterinary Sciences, 2015 Gingival overgrowth is an uncommon adverse effect of cyclosporine administration in veterinary species. In people, gingival overgrowth is a common complication of cyclosporine administration for immunosuppression, generally following transplant ...
Alison Diesel, Karen Moriello
doaj +1 more source
Upregulation of lysyl oxidase expression in cyclosporin A-induced gingival overgrowth
Journal of Dental Sciences, 2009 Lysyl oxidase (LOX) is involved in the initial steps of converting soluble monomers of collagen and elastin into insoluble fibers in the extracellular matrix. LOX was found to be upregulated in some fibrotic diseases.
Chung-Hung Tsai +2 more
doaj +1 more source
Incidence of amlodipine-induced gingival overgrowth in the rural population of Loni
Journal of Indian Society of Periodontology, 2014 Aims: Since the incidence of gingival overgrowth induced by amlodipine remains poorly defined, this study was carried out with an aim to determine the incidence.
Avneesh Tejnani +6 more
doaj +1 more source
Journal of the Formosan Medical Association, 2015 The prominent side effect of the immunosuppressive drug cyclosporine A (CsA) is gingival overgrowth. Hypoxia-inducible factor (HIF)-1α regulates a wide variety of profibrogenic genes, which are closely associated with tissue fibrosis.
Chung-Hung Tsai +5 more
doaj +1 more source
Journal of Pharmacological Sciences, 2005 It is well-known that the anticonvulsant drug, phenytoin (PHT), induces gingival overgrowth as a side effect. The mechanism of PHT-induced gingival overgrowth, however, is not well understood.
Yasuka Tamamori +3 more
doaj +1 more source
Using saliva nitrite and nitrate levels as a biomarker for drug induced gingival overgrowth
Frontiers in Cellular and Infection Microbiology, 2015 Aim: Drug-induced gingival overgrowth has a multifactorial nature and the pathogenesis is still uncertain. It has been suggested that Nitric Oxide (NO) might play a role in the pathogenesis of drug-induced gingival overgrowth due to the contribution of ...
Erkan eSukuroglu +3 more
doaj +1 more source
Epithelial to Mesenchymal Transition in Gingival Overgrowth [PDF]
The American Journal of Pathology, 2010 Epithelial to mesenchymal transition (EMT) occurs normally in development. In pathology, EMT drives cancer and fibrosis. Medication with phenytoin, nifedipine, and cyclosporine-A often causes gingival overgrowth. Based partly on the histopathology of gingival overgrowth, the present study investigates the hypothesis that EMT could contribute to its ...
Siddika Selva, Sume +4 more
openaire +2 more sources
Periodontology 2000, EarlyView., 2023 Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis +5 more
wiley +1 more source
Localized Longstanding Chronic Inflammatory Gingival Overgrowth - A Case Report
King Khalid University Journal of Health Sciences, 2016 We report a young patient who presented with longstanding gingival swelling. Based on the clinical, radiological, and histopathology findings following excision, a diagnosis of localized longstanding chronic inflammatory gingival overgrowth was made ...
Shankar T. Gokhale +4 more
doaj +1 more source