Results 21 to 30 of about 4,991 (245)

Comprehensive Management of a Patient with Drug Induced Gingival Overgrowth and Metabolic Syndrome [PDF]

open access: yes, 2021
Periodontitis and metabolic syndrome demonstrate a bidirectional relationship complicated by multiple risk factors. Gingival overgrowth (GO) is a manifestation of exaggerated inflammatory response of the gingivae in response to biofilm and varying local ...
B M C A Bandaranayake, A Tilakaratne
core   +1 more source

Angiotensin II Levels in Gingival Tissues from Healthy Individuals, Patients with Nifedipine Induced Gingival Overgrowth and Non Responders on Nifedipine [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Context: The Renin Angiotensin system has been implicated in the pathogenesis of Drug Induced Gingival Overgrowth (DIGO), a fibrotic condition, caused by Phenytoin, Nifedipine and Cyclosporine.
Anitha Balaji   +2 more
doaj   +1 more source

Conflation of gingival overgrowth and schwannoma [PDF]

open access: yesBMJ Case Reports, 2014
The authors describe a seminal case report of a 10-year-old boy with enlarged gingivae in relation to his maxillary anterior teeth. The lesion, provisionally diagnosed as idiopathic gingival enlargement, was completely excised and divided into two sections.
Parth, Purwar   +3 more
openaire   +2 more sources

Gingival Overgrowth as a complication of kidney transplantation – Nepali perspective

open access: yesNepalese Medical Journal, 2019
Gingival Overgrowth is a known and common complication with multifactorial etiology seen in kidney transplant recipients. Gingival Overgrowth is induced in kidney transplant recipients by Cyclosporin A and Calcium Channel Blockers that are frequently ...
Swosti Thapa   +6 more
doaj   +1 more source

Cyclosporine A: Novel concepts in its role in drug-induced gingival overgrowth

open access: yesDental Research Journal, 2015
Cyclosporine is a selective immunosuppressant that has a variety of applications in medical practice. Like phenytoin and the calcium channel blockers, the drug is associated with gingival overgrowth.
Deepa Ponnaiyan, Visakan Jegadeesan
doaj   +1 more source

Medical Management of Cyclosporine-Induced Gingival Overgrowth Using Oral Azithromycin in Six Dogs

open access: yesVeterinary Sciences, 2015
Gingival overgrowth is an uncommon adverse effect of cyclosporine administration in veterinary species. In people, gingival overgrowth is a common complication of cyclosporine administration for immunosuppression, generally following transplant ...
Alison Diesel, Karen Moriello
doaj   +1 more source

The modulation of hypoxia-inducible factor-1α/plasminogen activator inhibitor-1 axis in human gingival fibroblasts stimulated with cyclosporine A

open access: yesJournal of the Formosan Medical Association, 2015
The prominent side effect of the immunosuppressive drug cyclosporine A (CsA) is gingival overgrowth. Hypoxia-inducible factor (HIF)-1α regulates a wide variety of profibrogenic genes, which are closely associated with tissue fibrosis.
Chung-Hung Tsai   +5 more
doaj   +1 more source

Establishment of Rat Model of Drug-Induced Gingival Overgrowth Induced by Continuous Administration of Phenytoin

open access: yesJournal of Pharmacological Sciences, 2005
It is well-known that the anticonvulsant drug, phenytoin (PHT), induces gingival overgrowth as a side effect. The mechanism of PHT-induced gingival overgrowth, however, is not well understood.
Yasuka Tamamori   +3 more
doaj   +1 more source

Epithelial to Mesenchymal Transition in Gingival Overgrowth [PDF]

open access: yesThe American Journal of Pathology, 2010
Epithelial to mesenchymal transition (EMT) occurs normally in development. In pathology, EMT drives cancer and fibrosis. Medication with phenytoin, nifedipine, and cyclosporine-A often causes gingival overgrowth. Based partly on the histopathology of gingival overgrowth, the present study investigates the hypothesis that EMT could contribute to its ...
Siddika Selva, Sume   +4 more
openaire   +2 more sources

Assessment of Gingival Status and Gingival Overgrowth among Immunosuppressed Patients in Universiti Sains Malaysia Hospital

open access: yes, 2021
Drug-induced gingival overgrowth (DIGO) is defined as an abnormal growth of the gingiva due to adverse effect of some drugs such as immunosuppressant, calcium channel blocker, and anticonvulsant.
Mat Zaid, Syamimi Izzati   +2 more
core   +1 more source

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