Drug-Induced Gingival Overgrowth: A Pilot Study on the Effect of Diphenylhydantoin and Gabapentin on Human Gingival Fibroblasts. [PDF]
Introduction. The administration of several classes of drugs can lead to the onset of gingival overgrowth: anticonvulsants, immunosuppressants, and calcium channel blockers.
Lauritano D +5 more
europepmc +2 more sources
Initial periodontal therapy for seven patients with aplastic anemia and drug-induced gingival overgrowth: a case series report [PDF]
Background Patients with aplastic anemia are at increased risk of bleeding, which often limits conventional periodontal treatment. Although drug-induced gingival overgrowth is well-documented, its management in this high-risk population has not been ...
Xinxin Lv +6 more
doaj +2 more sources
Drug-Induced Gingival Overgrowth: The Effect of Cyclosporin A and Mycophenolate Mophetil on Human Gingival Fibroblasts. [PDF]
Drug-induced gingival overgrowth may occur after a chronic administration of three classes of systemic drugs: Anticonvulsants, immunosuppressants, and calcium channel blockers. This study aimed to investigate how cyclosporin A and mycophenolate mophetil (
Lauritano D +4 more
europepmc +2 more sources
Amlodipine-induced gingival overgrowth
Gingival overgrowth represents an over-exuberant response to a variety of local and systemic conditions. Certain anticonvulsants, immuno-suppressive drugs and a number of calcium channel blockers have been shown to produce similar gingival overgrowths in
Triveni M, Rudrakshi C, Mehta D
doaj +3 more sources
Periodontal Management of Cyclosporin A-Induced Gingival Overgrowth: A Nonsurgical Approach
Gingival overgrowth is a major and frequent unwanted effect accompanying the chronic usage of antihypertensive, anticonvulsant, and immunosuppressant drugs.
Rayhana Malek +2 more
doaj +2 more sources
Efficacy of AZM therapy in patients with gingival overgrowth induced by Cyclosporine A: a systematic review [PDF]
Background In daily clinical practice of a dental department it's common to find gingival overgrowth (GO) in periodontal patients under treatment with Cyclosporine A (CsA).
Deli Giorgio +6 more
doaj +2 more sources
Gingival overgrowth in fixed orthodontic therapy. [PDF]
The oral mucosa can suffer a series of traumatic injuries from various causes (bacterial plaque, tartar, fillings, incorrectly adapted prosthesis). A risk factor generating periodontal diseases is represented by fixed orthodontic therapy, if the forces exerted on it are excessive.
Rădeanu AC +5 more
europepmc +3 more sources
Cyclosporine A Causes Gingival Overgrowth by Promoting Entry into the S Phase at the G1/S Cell Cycle Checkpoint in Gingival Fibroblasts Exposed to Lipopolysaccharide [PDF]
Objectives: Cyclosporine A promotes gingival fibrosis by enhancing the proliferation of gingival fibroblasts, leading to gingival overgrowth. The population of gingival fibroblasts is regulated by cell cycle machinery, which balances cell growth and ...
Reiri Takeuchi +11 more
doaj +2 more sources
Gingival overgrowth during orthodontic treatment and its management. [PDF]
Rathod AD, Jaiswal P.
europepmc +2 more sources
Idiopathic gingival fibromatosis with massive gingival overgrowth: A rare case report.
Idiopathic gingival overgrowth can present itself as a part of syndrome or as an isolated entity. This is a case report of a massive gingival enlargement in a 12-year-old female child with nonsyndromic gingival fibromatosis, which was treated by ...
Sharma S +4 more
europepmc +2 more sources

