Results 111 to 120 of about 4,991 (245)

The role of acquired host immunity in periodontal diseases

Periodontology 2000, EarlyView.
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane, David F. Lappin, Shauna Culshaw   +2 more
wiley   +1 more source

[Cyclosporin-A induced gingival overgrowth--strain differences in the rats].

Shoni shikagaku zasshi. The Japanese journal of pedodontics, 1991
Cyclosporin-A (CsA) which is an effective immunosuppressive agent to control the rejection of organ transplants causes gingival overgrowth as one of accompanying side effects. However, the mechanism of this particular gingival overgrowth still remains unclear.
Adachi, Chiaki, Kitamura, Kyoichi, Kato, Kazuo, Yoshida, Mika, Morisaki, Ichijiro, Sobue, Shizuo   +5 more
openaire   +2 more sources

The oral microbiota and periodontal health in orthodontic patients

Periodontology 2000, EarlyView.
Abstract The oral microbiota develops within the first 2 years of childhood and becomes distinct from the parents by 4 years‐of‐age. The oral microbiota plays an important role in the overall health/symbiosis of the individual. Deviations from the state of symbiosis leads to dysbiosis and an increased risk of pathogenicity.
Brandon W. Peterson, Geerten‐Has Tjakkes, Anne‐Marie Renkema, David J. Manton, Yijin Ren   +4 more
wiley   +1 more source

Periodontal and orthodontic management of impacted canines

Periodontology 2000, EarlyView.
Abstract The maxillary and mandibular canines are described by many clinicians as the “cornerstone” of the arch. When in their optimal position, they play a critical role in providing a well‐balanced occlusal scheme that contributes toward functional as well as neuromuscular stability, harmony, esthetics, and dentofacial balance.
Mohammad Qali, Chenshuang Li, Chun‐Hsi Chung, Nipul Tanna   +3 more
wiley   +1 more source

Drug-induced gingival hyperplasia: An in vitro study using amlodipine and human gingival fibroblasts

International Journal of Immunopathology and Pharmacology, 2019
Gingival overgrowth is a serious side effect that accompanies the use of amlodipine. Several conflicting theories have been proposed to explain the fibroblast’s function in gingival overgrowth.
Dorina Lauritano, Marcella Martinelli, Alessandro Baj, Giada Beltramini, Valentina Candotto, Francesco Ruggiero, Annalisa Palmieri   +6 more
doaj   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Connective Tissue Growth Factor in Drug‐Induced Gingival Overgrowth

, 2001
Background: Drug-induced gingival overgrowth is a known side effect of certain chemotherapeutic agents used for the treatment of systemic disorders. The pathogenesis and mechanisms responsible for this condition are not fully understood.
Uzel, MI, Cem Uygur, Sheff, MC, Hsiang‐Hsi Hong, Michael C. Sheff, Hong, HH, Philip C. Trackman, M. Ilhan Uzel, Erhan Firatli, Trackman, PC, Firatli, E, Uygur, C, Kantarci, A, Alpdogan Kantarci   +13 more
core   +1 more source

Engineered surface strategies to manage dental implant‐related infections

Periodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza, Bruna E. Nagay, Rodrigo Martins, Martinna Bertolini, Jamil A. Shibli, Conrado Aparicio, Magda Feres, Valentim A. R. Barão   +7 more
wiley   +1 more source

The role of phosphatase and tensin homolog in drug-induced gingival overgrowth

, 2014
Background and Objective We proposed that phosphatase and tensin homolog (PTEN) might be one of the signaling proteins that alter the balance between cell growth and cell death in drug-induced gingival overgrowth. The aim of this study was to investigate
Arik, N., Cetinkaya, B. O., Keles, G. C., Pamuk, F., Ayas, B., Ozfidan, G. K., Kayisli, U.   +6 more
core   +1 more source

Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?

Periodontology 2000, EarlyView.
Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni, Yoshinori Shirakata, Lorenzo Marini, Darko Božić, Richard J. Miron, Roberto Rotundo, Andreas Stavropoulos, Anton Sculean   +7 more
wiley   +1 more source