Results 11 to 20 of about 8,922 (257)

Phenytoin- and amlodipine-induced gingival overgrowth

open access: goldJournal of Dental Sciences, 2012
Drug-induced gingival overgrowth is an adverse event associated with three types of drugs, i.e., anticonvulsants, immunosuppressants, and calcium-channel blockers.
Ching-Wen Chang   +2 more
doaj   +2 more sources

Cyclosporine A Causes Gingival Overgrowth by Promoting Entry into the S Phase at the G1/S Cell Cycle Checkpoint in Gingival Fibroblasts Exposed to Lipopolysaccharide [PDF]

open access: yesDiseases
Objectives: Cyclosporine A promotes gingival fibrosis by enhancing the proliferation of gingival fibroblasts, leading to gingival overgrowth. The population of gingival fibroblasts is regulated by cell cycle machinery, which balances cell growth and ...
Reiri Takeuchi   +11 more
doaj   +2 more sources

Gingival overgrowth in fixed orthodontic therapy. [PDF]

open access: yesRom J Morphol Embryol
The oral mucosa can suffer a series of traumatic injuries from various causes (bacterial plaque, tartar, fillings, incorrectly adapted prosthesis). A risk factor generating periodontal diseases is represented by fixed orthodontic therapy, if the forces exerted on it are excessive.
Rădeanu AC   +5 more
europepmc   +3 more sources

Amlodipine-induced gingival overgrowth

open access: yesJournal of Indian Society of Periodontology, 2009
Gingival overgrowth represents an over-exuberant response to a variety of local and systemic conditions. Certain anticonvulsants, immuno-suppressive drugs and a number of calcium channel blockers have been shown to produce similar gingival overgrowths in
Triveni M, Rudrakshi C, Mehta D
doaj   +3 more sources

Establishment of Rat Model of Drug-Induced Gingival Overgrowth Induced by Continuous Administration of Phenytoin

open access: bronzeJournal of Pharmacological Sciences, 2005
It is well-known that the anticonvulsant drug, phenytoin (PHT), induces gingival overgrowth as a side effect. The mechanism of PHT-induced gingival overgrowth, however, is not well understood.
Yasuka Tamamori   +3 more
doaj   +3 more sources

Periodontal Management of Cyclosporin A-Induced Gingival Overgrowth: A Nonsurgical Approach [PDF]

open access: yesCase Reports in Dentistry, 2019
Gingival overgrowth is a major and frequent unwanted effect accompanying the chronic usage of antihypertensive, anticonvulsant, and immunosuppressant drugs.
Rayhana Malek   +2 more
doaj   +2 more sources

Cyclosporine A causes gingival overgrowth via reduced G1 cell cycle arrest in gingival fibroblasts. [PDF]

open access: goldPLoS One
Takeuchi R   +12 more
europepmc   +3 more sources

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