Phenytoin- and amlodipine-induced gingival overgrowth
Drug-induced gingival overgrowth is an adverse event associated with three types of drugs, i.e., anticonvulsants, immunosuppressants, and calcium-channel blockers.
Ching-Wen Chang +2 more
doaj +2 more sources
Cyclosporine A Causes Gingival Overgrowth by Promoting Entry into the S Phase at the G1/S Cell Cycle Checkpoint in Gingival Fibroblasts Exposed to Lipopolysaccharide [PDF]
Objectives: Cyclosporine A promotes gingival fibrosis by enhancing the proliferation of gingival fibroblasts, leading to gingival overgrowth. The population of gingival fibroblasts is regulated by cell cycle machinery, which balances cell growth and ...
Reiri Takeuchi +11 more
doaj +2 more sources
Gingival overgrowth in fixed orthodontic therapy. [PDF]
The oral mucosa can suffer a series of traumatic injuries from various causes (bacterial plaque, tartar, fillings, incorrectly adapted prosthesis). A risk factor generating periodontal diseases is represented by fixed orthodontic therapy, if the forces exerted on it are excessive.
Rădeanu AC +5 more
europepmc +3 more sources
Amlodipine-induced gingival overgrowth
Gingival overgrowth represents an over-exuberant response to a variety of local and systemic conditions. Certain anticonvulsants, immuno-suppressive drugs and a number of calcium channel blockers have been shown to produce similar gingival overgrowths in
Triveni M, Rudrakshi C, Mehta D
doaj +3 more sources
It is well-known that the anticonvulsant drug, phenytoin (PHT), induces gingival overgrowth as a side effect. The mechanism of PHT-induced gingival overgrowth, however, is not well understood.
Yasuka Tamamori +3 more
doaj +3 more sources
Periodontal Management of Cyclosporin A-Induced Gingival Overgrowth: A Nonsurgical Approach [PDF]
Gingival overgrowth is a major and frequent unwanted effect accompanying the chronic usage of antihypertensive, anticonvulsant, and immunosuppressant drugs.
Rayhana Malek +2 more
doaj +2 more sources
Conventional Gingivectomy Procedure in the Management of Orthodontic-Induced Gingival Overgrowth: A Case Report. [PDF]
Dalal AM, Oza RR, Shirbhate U, Gurav T.
europepmc +3 more sources
Gingival overgrowth during orthodontic treatment and its management. [PDF]
Rathod AD, Jaiswal P.
europepmc +2 more sources
Cyclosporine A causes gingival overgrowth via reduced G1 cell cycle arrest in gingival fibroblasts. [PDF]
Takeuchi R +12 more
europepmc +3 more sources
Drug-Induced Gingival Overgrowth-Molecular Aspects of Drug Actions. [PDF]
Droździk A, Droździk M.
europepmc +3 more sources

