Results 51 to 60 of about 606,768 (255)

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Regulation of matrix remodelling phenotype in gingival fibroblasts by substratum topography [PDF]

Journal of Cellular and Molecular Medicine, 2015
AbstractGingival connective tissue often has a composition resembling that of scar surrounding dental implant abutments. Increased cell adhesion, α‐smooth muscle actin (α‐SMA) expression and increased extracellular matrix deposition are a hallmark of fibrotic cells, but how topographic features influence gingival fibroblast adhesion and adoption of the
Kim, Shawna S, Wen, Weiyan, Prowse, Paul, Hamilton, Douglas W   +3 more
openaire   +2 more sources

Gingival tissue samples from periodontitis patients demonstrate epithelial–mesenchymal transition phenotype

, 2023
Objective: To determine the expression of key epithelial–mesenchymal transition (EMT) markers in gingival tissue samples collected from patients with periodontitis.
Saif S. Saliem, Abdullah, Bashar H., Saliem, Saif S., Ali A. Abdulkareem, Bede, Salwan Y., Cooper, Paul R., Milward, Michael R., Paul R. Cooper, Bashar H. Abdullah, Michael R. Milward, Abdulkareem, Ali A., Salwan Y. Bede   +11 more
core   +1 more source

PIAS3 CircRNA‐Loaded Lipid Nanoparticles Restore ALOX15 SUMOylation to Suppress Cementoblast Ferroptosis and Attenuate Orthodontically Induced Root Resorption

Advanced Science, EarlyView.
Orthodontic compression suppresses PIAS3 expression in cementoblasts, impairing ALOX15 SUMOylation and ubiquitin‐mediated degradation, which leads to ALOX15 accumulation, lipid peroxidation, ferroptosis, and osteoclastogenesis. Local delivery of PIAS3 circRNA‐loaded lipid nanoparticles restores the PIAS3–ALOX15 regulatory pathway, alleviates ...
Yifei Hou, Chongzheng Yan, Xinrui Xu, Zihan Yang, Xinhui Wu, Hongxu Zhao, Xuan Song, Jianing Zhang, Yijing Li, Aohua Yang, Xiamei Lu, Yi Liu   +11 more
wiley   +1 more source

Association of Prx Gene Expression with the Gingival Phenotype

Modern Approaches in Dentistry and Oral Health Care, 2021
In addition to their role in development Prx genes have important roles in cell proliferation and migration [1]. Smooth muscle cells transfected with rat Prx1 showed increased proliferation [1]. Moreover, treatment of fibroblasts in vitro with morpholino oligos designed to specifically inhibit Prx1 and Prx2 protein expression resulted in downregulation
openaire   +1 more source

PERIODONTAL PHENOTYPE: A CLINICAL AND CURRENT VIEW

Revista Naval de Odontologia On Line, 2021
One of the essential elements to achieving smile esthetics is the phenotype and gingival contour, which with their architecture influence the size of dental crowns.
Lucas Mendes Gabri, Victor Gila Gomes de Mattos, Luis Paulo Diniz Barreto, Marcela Melo dos Santos   +3 more
doaj   +1 more source

Gingival phenotypes and their relation to age, gender and other risk factors [PDF]

BMC Oral Health, 2020
AbstractBackgroundCareful consideration and assessment of the type of phenotype has gained a fundamental importance in the treatment planning for any patient. We evaluated the prevalence of gingival phenotypes in a sample of Yemeni population and to explore its relationships to gender, age and other risk factors.MethodsThis cross-sectional study was ...
openaire   +3 more sources

Variable grouping patterns in primates: A test of the better competitor hypothesis in male Verreaux's sifaka (Propithecus verreauxi)

The Anatomical Record, EarlyView.
Abstract Intraspecific variation in social organization (IVSO) within primate populations can arise due to male mating competition. Verreaux's sifaka (Propithecus verreauxi) populations exhibit both single‐male and multi‐male groups, providing an opportunity to examine the relationship between male competitive ability and social organization.
Lemeng Li, Stacey R. Tecot, Rebecca J. Lewis   +2 more
wiley   +1 more source

Distribution of clinical characteristics of gingival phenotype in healthy patients

, 2019
Introduction Gingival phenotype determination enables a better understanding of intra and interindividual clinical variations in healthy periodontal tissues.
Bruno César de Vasconcelos GURGEL (5763893), Lidya Nara Marques de ARAÚJO (5763875), Samuel Batista BORGES (5996840)   +2 more
core   +1 more source