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Acta pharmacologica Sinica, 2001
To compare the effect of ginsenoside Rg1 and its metabolite Rh1 on proinflammatory cytokines and their mRNA expression by THP-1 cells.Human peripheral blood mononuclear cells (PBMC) were incubated with Rg1 and Rh1 at concentrations of 0.1, 1, 10, and 100 mg/L, and the cell proliferation was measured 24 h after incubation.
Y, Wang +5 more
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To compare the effect of ginsenoside Rg1 and its metabolite Rh1 on proinflammatory cytokines and their mRNA expression by THP-1 cells.Human peripheral blood mononuclear cells (PBMC) were incubated with Rg1 and Rh1 at concentrations of 0.1, 1, 10, and 100 mg/L, and the cell proliferation was measured 24 h after incubation.
Y, Wang +5 more
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Feasibility study of ginsenoside Rg1 administrated via intranasal route
China Journal of Chinese Matera Medica, 2010To study the feasibility of ginsenoside Rg1 administrated from nasal route.The safty of ginsenoside Rg1 was evaluated by testing cilia movement of the in situ toad palate model. The stability of ginsenoside Rg1 to nasal enzymes and pH was evaluated by HPLC method.
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Ginsenoside RG1 and corticosteroid receptors in rat brain.
Endocrinologia japonica, 1987Old (28 months) male Wistar rats were treated chronically for two weeks with ginsenoside Rg1 or with vehicle delivered via sc implanted Alzet mini-pumps (rate of ginsenoside release 2.4 micrograms/0.5 microliter/h). The number of Type 1 corticosterone-preferring receptor sites (CR) and Type 2 glucocorticoid receptors (GR) was measured in the cytosol of
de Kloet, E R +4 more
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Ginsenoside Rg1 inhibits the TSLP production in allergic rhinitis mice
Immunopharmacology and Immunotoxicology, 2013Recent study reports that Korean red ginseng reduces the nasal allergic inflammatory reaction in an allergic murine model. However, the contribution of ginsenoside Rg1 (RG1) and its mechanisms on allergic rhinitis (AR) have not been elucidated. In this study, we evaluated the important activities of RG1 in the ovalbumin (OVA)-induced AR mice.
Hyun-A, Oh +3 more
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Biotechnology Letters, 2012
Ginsenosides Re and Rg1 were transformed by recombinant β-glucosidase (Bgp1) to ginsenosides Rg2 and Rh1, respectively. The bgp1 gene consists of 2,496 bp encoding 831 amino acids which have homology to the glycosyl hydrolase families 3 protein domain.
Lin-Hu, Quan +5 more
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Ginsenosides Re and Rg1 were transformed by recombinant β-glucosidase (Bgp1) to ginsenosides Rg2 and Rh1, respectively. The bgp1 gene consists of 2,496 bp encoding 831 amino acids which have homology to the glycosyl hydrolase families 3 protein domain.
Lin-Hu, Quan +5 more
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Preparation and Properties of Ginsenoside Rg1 Molecularly Imprinted Polymers
Advanced Materials Research, 2012Molecularly imprinted polymers (MIPs) were prepared by precipitation polymerization with ginsenoside Rg1 as the template molecule. The morphology of MIPs was characterized by scanning electronmicroscope (SEM) and its static adsorption capacity was measured by the Scatchard equation.
Li Na Yi +3 more
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[Immunoregulatory effects of ginsenoside Rg1 in aged rats].
Yao xue xue bao = Acta pharmaceutica Sinica, 1996It has been well documented that the immune function declines with age in the human and animals. The possible causes for the decline are the inability of lymphocytes to proliferate in response to mitogenic stimulation and the decrease of IL-2 production.
M, Liu, J T, Zhang
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A one-step immunochromatographic assay for detecting ginsenosides Rb1 and Rg1
Analytical and Bioanalytical Chemistry, 2004An immunochromatographic strip test has been developed for detecting ginsenosides Rb1 (G-Rb1) and Rg1 (G-Rg1). This qualitative assay system is useful as a rapid screening method for detecting G-Rb1 and G-Rg1 in plants and plant preparations. Our assay is a competitive immunoassay that uses anti-G-Rb1 and anti-G-Rg1 monoclonal antibodies (MAbs) and a ...
Waraporn, Putalun +3 more
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[Pharmacokinetics and bioavailability of ginsenoside Rg1 in rats].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014To investigate the pharmacokinetics and bioavailability of ginsenoside Rg1 in rats.Ginsenoside Rg1 was oral administered or intravenous administered to each rat. The plasma concentration of ginsenoside Rg1 was estimated by RP-HPLC. 3P97 software was used to calculate pharmacokinetic parameters.Main parameters of ginsenoside Rg1 after oral or ...
Zhen-Yuan, Tan +3 more
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Antitumor-Promoting Activities of Ginsenoside Rg1 and Panax notoginseng
1997As a continuation of our chemical and biological studies on potential antitumor promoters (chemopreventive agents), we carried out primary screening of many kinds of natural products using their inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12–0-tetradecanoylphorbol-13-acetate (TPA). The root of Panax notoginseng
Takao Konoshima +2 more
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