Results 101 to 110 of about 20,751 (192)
The Immune Microenvironment in Liver Cancer: From Analysis to Targeting
Advanced Science, Volume 12, Issue 47, December 18, 2025.This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan +5 more
wiley +1 more source
Frontiers in Pharmacology, 2018 Atherosclerosis (AS) in diabetic patients is often associated with low stability, which might be largely attributed to unfavorable macrophage polarization and increased inflammatory response induced by hyperglycaemia.
Mengqi Guo +7 more
doaj +1 more source
eFood, Volume 6, Issue 6, December 2025.In light of the steadily increasing incidence of diabetic nephropathy (DN), this review explores the potential of edible natural products to slow disease progression, addressing the limitations of conventional clinical drug therapies. Key findings show that ginsenosides, the active compounds in edible ginseng, regulate lipid autophagy, reducing ...
Rui Zhang +7 more
wiley +1 more source
Simultaneous determination of 3 kinds of rare ginsenosides in fermented ginseng by HPLC [PDF]
Zhongguo niangzaoA method for simultaneous determination of 3 kinds of rare ginsenoside Rg3, Rg3(R) and Rg5 in fermented ginseng by HPLC was established. The samples were separated by Xtimate-C18 (4.6 mm×250 mm, 5 μm) using acetonitrile and 0.1% phosphoric acid ...
LI Chunyang, CHENG Qian, CHEN Zhao, WANG Tao, PENG Ning, CHEN Zhixian
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Ginsenoside Rg3 Alleviates Antithyroid Cancer Drug Vandetanib-Induced QT Interval Prolongation.
Oxidative medicine and cellular longevity, 2021 Inhibition of human ether-a-go-go-related gene (hERG) potassium channel is responsible for acquired long QT syndromes, which leads to life-threatening cardiac arrhythmia. A multikinase inhibitor, vandetanib, prolongs the progression-free survival time in advanced medullary thyroid cancer.
Zhang, Juan +7 more
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Antitumor effects of ginsenoside Rg3 on human hepatocellular carcinoma cells
Molecular Medicine Reports, 2012 The antitumor effects of ginsenoside Rg3 have been reported in several kinds of human malignant tumors. The purpose of this study was to investigate whether ginsenoside Rg3 can inhibit the growth of human hepatocellular carcinoma cell lines and to discuss the possible molecular mechanism(s).
Chunle, Zhang +5 more
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Journal of Ginseng Research, 2017 Background: Korean Red Ginseng has been used for several decades to treat many diseases, enhancing both immunity and physical strength. Previous studies have documented the therapeutic effects of ginseng, including its anticancer, antiaging, and anti ...
Dahye Jeong +7 more
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Journal of Pharmacopuncture, 2010 Objectives: The aim of this experiment is to provide an objective differentiation of cultivated ginseng, cultivated wild ginseng, and wild ginseng through component analysis, and to know the change of ginsenoside components in the process for making red ...
Jeong HS +4 more
doaj +1 more source
Journal of Ginseng Research, 2019 Background: Ginsenoside Rg3 (G-Rg3) is the major bioactive ingredient of Panax ginseng and has many pharmacological effects, including antiadipogenic, antiviral, and anticancer effects.
Ji-Ye Kee, Seung-Heon Hong
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Stereospecific Effects of Ginsenoside Rg3 Epimers on Swine Coronary Artery Contractions
Biological and Pharmaceutical Bulletin, 2006 Previous reports have shown that ginseng saponins, the active ingredients of Panax ginseng, induce relaxation of hormone- or high K(+)-induced blood vessel contraction. We recently demonstrated that 20(R)- and 20(S)-ginsenoside Rg(3) epimers regulate ion channel activities in a stereospecific manner.
Jong-Hoon, Kim +10 more
openaire +3 more sources