Results 81 to 90 of about 4,514 (169)

Effects of ginsenoside Rg3 on apoptosis in A375.S2 melanoma cells

Translational Cancer Research, 2019
Malignant melanoma is the most aggressive skin cancer, and metastatic malignant melanoma is very difficult to treat. Ginsenoside Rg3 extracted from ginseng has been reported to have anticancer effects in various kinds of cancer. It has also been reported that Rg3 induced apoptosis and inhibited metastasis of melanoma cells derived from rats, but ...
Kim, Joo Hyoung, Bae, Yong Chan, Lee, Jae Woo, Choi, June Seok, Bae, Seong Hwan   +4 more
openaire   +2 more sources

Antitumor effects of ginsenoside Rg3 on human hepatocellular carcinoma cells

Molecular Medicine Reports, 2012
The antitumor effects of ginsenoside Rg3 have been reported in several kinds of human malignant tumors. The purpose of this study was to investigate whether ginsenoside Rg3 can inhibit the growth of human hepatocellular carcinoma cell lines and to discuss the possible molecular mechanism(s).
Chunle, Zhang, Lingjun, Liu, Yang, Yu, Bin, Chen, Chengwei, Tang, Xiao, Li   +5 more
openaire   +3 more sources

Ginsenoside Rg3 suppresses mast cell–mediated allergic inflammation via mitogen-activated protein kinase signaling pathway

Journal of Ginseng Research, 2019
Background: Ginsenoside Rg3 (G-Rg3) is the major bioactive ingredient of Panax ginseng and has many pharmacological effects, including antiadipogenic, antiviral, and anticancer effects.
Ji-Ye Kee, Seung-Heon Hong
doaj   +1 more source

Change of Ginsenoside Rg3 [PDF]

Journal of Ginseng Research, 2009
Mi-Ra Lee, Beom-Sik Yun, Bai-Shen Sun, Lei Liu, Dong-Liang Zhang, Chun-Yan Wang, Zhen Wang, Sun-Young Ly, Eun-Kyung Mo, Chang-Keun Sung   +9 more
openaire   +1 more source

Effects of 20(R)-Ginsenoside Rg3 and 20(S)-Ginsenoside Rg3 on the migration and invasion of HaCaT cells

Yakhak Hoeji, 2021
Sang-Won Kim, Young-Chan Noh, So-Yeon Park, Mijin Lee, Hui-Ji Choi, Gyu-Yong Song, Hangun Kim   +6 more
openaire   +1 more source

Component analysis of cultivated ginseng, cultivated wild ginseng, and wild ginseng and the change of ginsenoside components in the process of red ginseng

Journal of Pharmacopuncture, 2010
Objectives: The aim of this experiment is to provide an objective differentiation of cultivated ginseng, cultivated wild ginseng, and wild ginseng through component analysis, and to know the change of ginsenoside components in the process for making red ...
Jeong HS, Lim CS, Cha BC, Choi SH, Kwon KR   +4 more
doaj   +1 more source

Ginsenoside Rg3-enriched red ginseng extract inhibits platelet activation and in vivo thrombus formation

Journal of Ginseng Research, 2017
Background: Korean Red Ginseng has been used for several decades to treat many diseases, enhancing both immunity and physical strength. Previous studies have documented the therapeutic effects of ginseng, including its anticancer, antiaging, and anti ...
Dahye Jeong, Muhammad Irfan, Sung-Dae Kim, Suk Kim, Jun-Hwan Oh, Chae-Kyu Park, Hyun-Kyoung Kim, Man Hee Rhee   +7 more
doaj   +1 more source

Ginsenoside Rg3 Suppresses Proliferation and Induces Apoptosis in Human Osteosarcoma

BioMed Research International, 2018
Osteosarcoma is the most common primary malignancy of bone in children and the elderly. Recently, more and more researches have demonstrated that Ginsenoside Rg3 (Rg3) is involved in chemotherapy resistance in many cancer, making it a promising Chinese herbal monomer for oncotherapy.
Yi Li, Jinying Lu, Furong Bai, Yanan Xiao, Yiran Guo, Ziming Dong   +5 more
openaire   +2 more sources

Differential antiangiogenic and anticancer activities of the active metabolites of ginsenoside Rg3

Journal of Ginseng Research
Epimers of ginsenoside Rg3 (Rg3) have a low bioavailability and are prone to deglycosylation, which produces epimers of ginsenoside Rh2 (S-Rh2 and R-Rh2) and protopanaxadiol (S-PPD and R-PPD). The aim of this study was to compare the efficacy and potency of these molecules as anti-cancer agents.Crystal violet staining was used to study the anti ...
Maryam Nakhjavani, Eric Smith, Kenny Yeo, Yoko Tomita, Timothy J. Price, Andrea Yool, Amanda R. Townsend, Jennifer E. Hardingham   +7 more
openaire   +3 more sources

Ginsenoside Rg3 promotes the survival and migration of trophoblast cells in a rat model of gestational hypertension by regulating mir-100a/insulin growth factor-2 axis

World Journal of Traditional Chinese Medicine
Objective: Preeclampsia (PE) is a common complication during pregnancy. miR-100a is expressed in the placenta and regulates the survival and development of placental cells. Insulin growth factor-2 (IGF-2) may serve as its downstream target.
Xiu-Mei Fan, Li Yang, Gang Zhao, Sen-Ye Huo, Yan Gao   +4 more
doaj   +1 more source