Results 101 to 110 of about 6,327 (215)
iMeta, Volume 5, Issue 1, February 2026.Schematic representation showing that 20 (S)‐Rg3 improves mouse NASH. 20(S)‐Rg3 reduces OxPLs levels and ameliorates ferroptosis in the liver of NASH mice. Mechanistically, 20(S)‐Rg3 activates SPOP. Meanwhile, SPOP attenuates the ATF3‐mediated transcriptional repression of NUPR1 by enhancing the K48‐linked ubiquitination of ATF3.
Yibo Zong +9 more
wiley +1 more source
Phytotherapy of nephrotoxicity-induced by cancer drugs: An updated review [PDF]
, 2017 Context: Kidney is one of the vital organs maintaining homeostasis of body and thus dysfunction of kidney affects quality of life and health severely. Anticancer drugs, particularly chemotherapeutic agents, cause high toxicity leading kidney dysfunction ...
Asadi-Samani, Majid. +3 more
core +3 more sources
Pharmaceuticals, 2019 Ginsenoside Rg3 (Rg3) has two epimers, 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3), and while Rg3 itself has been reported to have anti-cancer properties, few studies have been reported on the anti-cancer effects of the different ...
Maryam Nakhjavani +8 more
doaj +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
MedComm, Volume 7, Issue 2, February 2026.Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
Journal of Ginseng Research, 2016 Background: Nephrotoxicity is a common side effect of medications. Panax ginseng is one of the best-known herbal medicines, and its individual constituents enhance renal function.
Myoung-Sik Han +11 more
doaj +1 more source
Ginsenoside Rg3 Improves Erectile Function in Streptozotocin-Induced Diabetic Rats
The Journal of Sexual Medicine, 2015 ABSTRACT Introduction Ginsenoside Rg3 is one of the active ingredients isolated from Panax ginseng C.A. Meyer. Previous studies demonstrated that Rg3 has antioxidant and neuroprotective abilities. Aim The purpose of this study was to ...
Tao, Liu +6 more
openaire +2 more sources
MedComm, Volume 7, Issue 2, February 2026.Traditional Chinese medicine (TCM) faces great challenges during the development of modern medicine. Utilizing novel technologies such as artificial intelligence (AI) and nanotechnology facilitates TCM with great potential in precision diagnosis and improved treatments efficacy.
Wenqi Yu +7 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.ABSTRACT Percutaneous coronary intervention (PCI) enables coronary revascularisation and restores haemodynamic stability but also carries risks of delayed complications including in‐stent restenosis (ISR), a chronic progressive disease with endovascular damage after PCI, which compromises the long‐term efficacy of PCI.
Xueli Lei +5 more
wiley +1 more source
Oral Rg1 supplementation strengthens antioxidant defense system against exercise-induced oxidative stress in rat skeletal muscles [PDF]
, 2012 BACKGROUND: Previous studies reported divergent results on nutraceutical actions and free radical scavenging capability of ginseng extracts. Variations in ginsenoside profile of ginseng due to different soil and cultivating season may contribute to the ...
Chia-Hua Kuo +10 more
core +1 more source
Network Pharmacology Analysis and Molecular Characterization of the Herbal Medicine Formulation Qi-Fu-Yin for the Inhibition of the Neuroinflammatory Biomarker iNOS in Microglial BV-2 Cells: Implication for the Treatment of Alzheimer’s Disease [PDF]
, 2020 Aberrant microglial activation drives neuroinflammation and neurodegeneration in Alzheimer's disease (AD). The present study is aimed at investigating whether the herbal formula Qi-Fu-Yin (QFY) could inhibit the inflammatory activation of cultured BV-2 ...
Chen, H +6 more
core +1 more source