Results 61 to 70 of about 6,327 (215)
Advances in Polymer Technology, 2020 Objective. To explore the effects and mechanism of ginsenoside Rg3 nanoparticles on the malignant behavior of non-small-cell lung cancer. Methods. The nanoparticle carriers were prepared by using an electrostatic system, and the coverage of ginsenoside ...
Weizheng Zhou +4 more
doaj +1 more source
Generation and Characterization of Monoclonal Antibody to Ginsenoside Rg3
Biological and Pharmaceutical Bulletin, 2009 While studying the mechanism of ginsenoside Rg3 (G-Rg3) on tumor inhibition, we produced monoclonal antibody to G-Rg3 for more specific investigation. We immunized Balb/c mice to G-Rg3 conjugated bovine serum albumin (BSA) by intraperitoneal injection and hybridized splenocytes from those immunized mice and myeloma cells.
Eun Ji, Joo +4 more
openaire +3 more sources
PLoS ONE, 2017 ObjectiveThis study aimed to investigate the link between the inhibitory effect of ginsenoside Rg3 on the ectopic endometrium growth and the VEGFR-2-mediated PI3K/Akt/mTOR signaling pathway, a mechanism known to inhibit angiogenesis and induce ectopic ...
Yang Cao +9 more
doaj +1 more source
Ginsenoside Rk1 is a novel inhibitor of NMDA receptors in cultured rat hippocampal neurons
Journal of Ginseng Research, 2020 Background: Ginsenoside Rk1, a saponin component isolated from heat-processed Panax ginseng Meyer, has been implicated in the regulation of antitumor and anti-inflammatory activities.
Nayeon Ryoo +6 more
doaj +1 more source
Frontiers in Pharmacology, 2018 Acute lung injury (ALI) is a common clinical disease with high morbidity in both humans and animals. Ginsenoside Rg3, a type of traditional Chinese medicine extracted from ginseng, is widely used to cure many inflammation-related diseases.
Jing Yang +7 more
doaj +1 more source
Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives
Precision Medical Sciences, EarlyView.Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley +1 more source
Anti-Metastasis Effects of Ginsenoside Rg3 in B16F10 Cells
Journal of Microbiology and Biotechnology, 2015 Ginsenoside Rg3 is a bioactive ginseng constituent that has been reported to have diverse pathological and physiological effects, including anti-inflammatory and anti-metastatic activities. Metastasis is one of the most important factors involved in patients with melanoma.
Seul Gi, Lee +2 more
openaire +2 more sources
Journal of Diabetes Investigation, EarlyView.Molecular mechanism of synergistic antagonism of ANGPTL4 and VEGF by ginsenoside Rg3 combined with ranibizumab, regulating the NRP/RhoA pathway to inhibit macular edema. ABSTRACT Aims This study investigated the molecular mechanisms by which ginsenoside Rg3 combined with ranibizumab alleviates diabetic macular edema (DME), focusing on antagonizing ...
Jiexin Yu, Xingyu Li, Yanli Liu
wiley +1 more source
Effects of a multi-herbal extract on type 2 diabetes [PDF]
, 2011 Background An aqueous extract of multi-hypoglycemic herbs of Panax ginseng C.A.Meyer, Pueraria lobata, Dioscorea batatas Decaisne, Rehmannia glutinosa, Amomum cadamomum Linné, Poncirus fructus and Evodia officinalis was investigated for its anti-diabetic
Jiyoung Yeo +3 more
core +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou +12 more
wiley +1 more source