Results 51 to 60 of about 4,514 (169)

Food and Medicinal Homologous Substances in Sleep Disorders Improvement: Current Advances and Future Perspectives

Food Frontiers, Volume 7, Issue 4, July 2026.
The schematic diagram illustrating the improvement mechanisms of six typical FMH substances and their main active ingredients in different sleep disorders. ABSTRACT Sleep integrates many brain and peripheral processes, profoundly influencing well‐being.
Wenjing Wen, Qili Li, Chenghao Lv, Jing Wen, Yihan Zhang, Yuhang Yi, Tao Li, Fang Wang, Yibo Luo, Si Qin   +9 more
wiley   +1 more source

Ginsenoside Rg3, a Gating Modifier of EAG Family K+ Channels [PDF]

Molecular Pharmacology, 2016
Ginsenoside 20(S)-Rg3 (Rg3) is a steroid glycoside that induces human ether-à-go-go-related gene type 1 (hERG1, Kv11.1) channels to activate at more negative potentials and to deactivate more slowly than normal. However, it is unknown whether this action is unique to hERG1 channels. Here we compare and contrast the mechanisms of actions of Rg3 on hERG1
Wei, Wu, Alison, Gardner, Frank B, Sachse, Michael C, Sanguinetti   +3 more
openaire   +2 more sources

Exploration and Characterization of Novel Glycoside Hydrolases from the Whole Genome of Lactobacillus ginsenosidimutans and Enriched Production of Minor Ginsenoside Rg3(S) by a Recombinant Enzymatic Process

Biomolecules, 2020
Background: Several studies have reported that ginsenoside Rg3(S) is effective in treating metastatic diseases, obesity, and various cancers, however, its presence in white ginseng cannot be estimated, and only a limited amount is present in red ginseng.
Muhammad Zubair Siddiqi, Sathiyaraj Srinivasan, Hye Yoon Park, Wan-Taek Im   +3 more
doaj   +1 more source

Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley   +1 more source

Ginsenoside Rg3 promotes inflammation resolution through M2 macrophage polarization

Journal of Ginseng Research, 2018
Background: Ginsenosides have been reported to have many health benefits, including anti-inflammatory effects, and the resolution of inflammation is now considered to be an active process driven by M2-type macrophages.
Saeromi Kang, Soo-Jin Park, Ae-Yeon Lee, Jin Huang, Hae-Young Chung, Dong-Soon Im   +5 more
doaj   +1 more source

Evaluating the Hepatoprotective Effect of Phyllanthus emblica and Panax ginseng Powders on Acetaminophen‐Induced Liver Fibrosis in a Rat Model

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Schematic illustration of the experimental design and the hepatoprotective effect of Phyllanthus emblica and Panax ginseng against acetaminophen (APAP)‐induced fibrosis in Wistar rats. APAP administration leads to NAPQI formation and accumulation, which causes GSH depletion and HSC activation. This ultimately becomes the primary cause of liver fibrosis.
Fiza Javed, Nourah Harbi Almutairi, Wardha Tariq, Mah Noor, Shiza Javed, Usman Haider, Ghalia Shamlan, Gholamreza Abdi, Rana Muhammad Aadil   +8 more
wiley   +1 more source

Two Ginseng UDP-Glycosyltransferases Synthesize Ginsenoside Rg3 and Rd [PDF]

Plant and Cell Physiology, 2014
Ginseng is a medicinal herb that requires cultivation under shade conditions, typically for 4-6 years, before harvesting. The principal components of ginseng are ginsenosides, glycosylated tetracyclic terpenes. Dammarene-type ginsenosides are classified into two groups, protopanaxadiol (PPD) and protopanaxatriol (PPT), based on their hydroxylation ...
Jung, SC Jung, Suk-Chae, Kim, W Kim, Woohyun, Park, SC Park, Sung Chul, Jeong, J Jeong, Jinkil, Park, MK Park, Myung Keun, Lim, S Lim, Soohwan, Lee, Y Lee, Yeon, Im, WT Im, Wan-Taek, Lee, JH Lee, Jun Hyoung, Choi, GT Choi, Gil-Tsu, Kim, SC Kim, Sun Chang   +10 more
openaire   +3 more sources

Ginsenoside Rg3 Ameliorates Stress of Broiler Chicks Induced by Escherichia coli Lipopolysaccharide

Frontiers in Veterinary Science, 2022
In broiler chicks, Escherichia coli lipopolysaccharide is a prominent cause for inflammatory damage and loss of immune homeostasis in broiler chicks. Ginsenosides have been shown to have anti-inflammatory and antioxidant effects. However, it has not been
Shicheng Bi, Yiwen Qu, Jianjian Shao, Jianrong Zhang, Weihao Li, Li Zhang, Jingxuan Ni, Liting Cao   +7 more
doaj   +1 more source

The Supporting Role of Natural Products as Effective Adjuvants in Cancer Immunotherapy

eFood, Volume 7, Issue 3, June 2026.
Natural products, as multi‐target and low‐toxicity adjuvants, enhance immune checkpoint inhibitor responses and reduce immune‐related adverse events through T cell reprogramming, microenvironment remodeling, and microbiota‐immune modulation. ABSTRACT Immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape of malignant tumors ...
Boyang Liu, Yubin Huang, Jianjun Deng, Zhijun Mao, Xue Bai, Longyang Ma, Jianhua Wang   +6 more
wiley   +1 more source

Inhibitory effect of ginsenoside Rg3 on ovarian cancer metastasis

Chinese Medical Journal, 2008
Ginsenosides are main components extracted from ginseng, and ginsenoside Rg3 is one of the most important parts. Ginsenoside Rg3 has been found to inhibit several kinds of tumor growth and metastasis. The present study was undertaken to investigate the effect of ginsenoside Rg3 on human ovarian cancer metastasis and the possible mechanism.The ...
Tian-Min, Xu, Man-Hua, Cui, Ying, Xin, Li-Ping, Gu, Xin, Jiang, Man-Man, Su, Ding-Ding, Wang, Wen-Jia, Wang   +7 more
openaire   +2 more sources