Results 31 to 40 of about 4,987 (188)

Network Analysis of 20S-Ginsenoside Rg3 Effect on Human Colorectal Adenocarcinoma Cell Line HT-29 [PDF]

open access: yesResearch Journal of Pharmacognosy, 2022
Background and objectives: 20S-Ginsenoside Rg3 is a pharmacological active compound of ginseng. Evidences indicate that S20-Rg3 as an anti-cancer factor plays role in prevention and treatment of cancer.
Mona Zamanian Azodi   +5 more
doaj   +1 more source

Relationship Between Ginsenoside Rg3 and Metabolic Syndrome [PDF]

open access: yesFrontiers in Pharmacology, 2020
Metabolic syndrome is an important public health issue and is associated with a more affluent lifestyle. Many studies of metabolic syndrome have been reported, but its pathogenesis remains unclear and there is no effective treatment. The ability of natural compounds to ameliorate metabolic syndrome is currently under investigation.
Hyunji Lee   +12 more
openaire   +3 more sources

Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway

open access: yesJournal of Ginseng Research, 2022
Background: Ginsenoside Rg3 is one of the main active ingredients in ginseng. Here, we aimed to confirm its protective effect on the heart function in transverse aortic coarctation (TAC)-induced heart failure mice and explore the potential molecular ...
Jingyu Ni   +11 more
doaj   +1 more source

Ginsenoside Rg3 attenuates fat accumulation in zebrafish with high-fat-diet-induced obesity

open access: yesPharmacological Research - Modern Chinese Medicine, 2022
Ginsenoside Rg3 is one of major steroidal saponins in Panax ginseng that has demonstrated several therapeutic effects. In this study, we investigated the effects of ginsenoside Rg3 on lipid accumulation in a high-fat diet (HFD) larval zebrafish model by ...
Fei Li   +4 more
doaj   +1 more source

Ginsenoside Rg3 Alleviates Cisplatin Resistance of Gastric Cancer Cells Through Inhibiting SOX2 and the PI3K/Akt/mTOR Signaling Axis by Up-Regulating miR-429

open access: yesFrontiers in Genetics, 2022
Platinum-based cytotoxic chemotherapy is considered the standard treatment for advanced gastric cancer (GC). However, cisplatin chemoresistance often occurs with the mechanisms being not well clarified, which results in the cancer recurrence and poor ...
Xiaofeng Wang   +4 more
doaj   +1 more source

Co-treatment with Ginsenoside 20(S)-Rg3 and Curcumin increases Radiosensitivity of MDA-MB-231 Cancer Cell Line [PDF]

open access: yesIranian Journal of Medical Sciences, 2021
Background: Breast cancer is the second most common cancer in women worldwide. Developing drugs increase the radiosensitivity effect of tumoral tissue, while protecting normal tissues has gained much attention.
Vahid Changizi   +2 more
doaj   +1 more source

Pharmacokinetic Profiling of Ginsenosides, Rb1, Rd, and Rg3, in Mice with Antibiotic-Induced Gut Microbiota Alterations: Implications for Variability in the Therapeutic Efficacy of Red Ginseng Extracts

open access: yesFoods, 2023
Ginsenoside Rg3 is reported to contribute to the traditionally known diverse effects of red ginseng extracts. Significant individual variations in the therapeutic efficacy of red ginseng extracts have been reported.
Jeon-Kyung Kim   +5 more
doaj   +1 more source

20(R)-ginsenoside Rg3, a product of high-efficiency thermal deglycosylation of ginsenoside Rd, exerts protective effects against scrotal heat-induced spermatogenic damage in mice

open access: yes, 2021
Heat stress (HS) reaction can lead to serious physiological dysfunction associated with cardiovascular and various organ diseases. Ginsenoside Rg3 (G-Rg3) is a representative component of ginseng rare saponin and can protect against multiple organs, also
Wang, Z   +9 more
core   +1 more source

Ginsenoside Rg3 Promotes Cell Growth Through Activation of mTORC1 [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Graphical AbstractGinsenoside Rg3 promotes cell growth through activation of mTORC1 and increasing mitochondrial biogenesis.
Wei Liu   +13 more
openaire   +3 more sources

The Content and Principle of the Rare Ginsenosides Produced from Gynostemma pentaphyllum after Heat Treatment

open access: yesMolecules, 2023
Ginsenoside Rg3, Rk1, and Rg5, rare ginsenosides from Panax ginseng, have many pharmacological effects, which have attracted extensive attention. They can be obtained through the heat treatment of Gynostemma pentaphyllum. In this study, scanning electron
Xin-Can Li   +5 more
doaj   +1 more source

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