Results 31 to 40 of about 4,514 (169)
Introduction: Non-small cell lung cancer (NSCLC) patients are particularly vulnerable to the Coronavirus Disease-2019 (COVID-19). Currently, no anti-NSCLC/COVID-19 treatment options are available.
Zhenjie Zhuang +5 more
doaj +1 more source
Stereospecificity of Ginsenoside Rg3 Action on Ion Channels
Ginsenosides, active ingredients of Panax ginseng, exist as stereoisomers depending on the position of the hydroxyl group on carbon-20; i.e. 20(R)-ginsenoside and 20(S)-ginsenoside are epimers. We have shown previously that the mixture of 20(R)- and 20(S)-ginsenosides regulates ion channel activity.
Sang Min, Jeong +9 more
openaire +2 more sources
Inflammation and oxidative stress lead to various acute or chronic diseases, including pneumonia, liver and kidney injury, cardiovascular and cerebrovascular diseases, metabolic diseases, and cancer.
Jing Wang +11 more
doaj +1 more source
Ginsenoside Rg3(S) is a primary bioactive component in ginseng, which has pharmacological effects and nutritional activities. In the present study, pulsed electric field (PEF)-assisted acid hydrolysis processing was used to convert major ginsenoside Rb1 ...
Lu Chengwen, Yin Yongguang
doaj +1 more source
Evaluation of the gastroprotective effects of 20 (S)-ginsenoside Rg3 on gastric ulcer models in mice
Background: Gastric ulcer (GU) is a common gastrointestinal disease that can be induced by many factors. Finding an effective treatment method that contains fewer side effects is important.
Kai Zhang +7 more
doaj +1 more source
Efficacy and mechanism of action of ginsenoside Rg3 on radiation proctitis in rats. [PDF]
AbstractObjectiveRadiation proctitis (RP) refers to rectal injury caused by radiation treatment of pelvic and retroperitoneal malignancies, which has a major impact on the treatment prognosis and quality of life of patients with cancer. The tetracyclic triterpene saponin monomer ginsenoside Rg3 (GRg3), the primary bioactive ingredient in ginseng ...
Li X, Lin L, Duan X, Dai J, Hu T, Cai H.
europepmc +4 more sources
Ginsenoside Rg3 for Chemotherapy-Induced Myelosuppression: A Meta-Analysis and Systematic Review
Patients with advanced cancer often undergo myelosuppression after receiving chemotherapy. However, severe myelosuppression results in treatment delay, and some can even be life-threatening.
Linlin Pan +4 more
doaj +1 more source
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Colon cancer, the third most frequent occurred cancer, has high mortality and extremely poor prognosis. Ginsenoside, the active components of traditional Chinese herbal medicine Panax ginseng, exerts antitumor effect in various cancers, including colon ...
Xin Sun +8 more
doaj +1 more source
Objective. To explore the effects and mechanism of ginsenoside Rg3 nanoparticles on the malignant behavior of non-small-cell lung cancer. Methods. The nanoparticle carriers were prepared by using an electrostatic system, and the coverage of ginsenoside ...
Weizheng Zhou +4 more
doaj +1 more source
Anti-Metastasis Effects of Ginsenoside Rg3 in B16F10 Cells
Ginsenoside Rg3 is a bioactive ginseng constituent that has been reported to have diverse pathological and physiological effects, including anti-inflammatory and anti-metastatic activities. Metastasis is one of the most important factors involved in patients with melanoma.
Seul Gi, Lee +2 more
openaire +2 more sources

