Results 31 to 40 of about 6,327 (215)
Frontiers in Genetics, 2022 Platinum-based cytotoxic chemotherapy is considered the standard treatment for advanced gastric cancer (GC). However, cisplatin chemoresistance often occurs with the mechanisms being not well clarified, which results in the cancer recurrence and poor ...
Xiaofeng Wang +4 more
doaj +1 more source
Journal of Ginseng Research, 2022 Background: Ginsenoside Rg3 and gemcitabine have mutual enhancing antitumor effects. However, the underlying mechanisms are not clear. This study explored the influence of ginsenoside Rg3 on Zinc finger protein 91 homolog (ZFP91) expression in pancreatic
Haixia Pan +4 more
doaj +1 more source
Co-treatment with Ginsenoside 20(S)-Rg3 and Curcumin increases Radiosensitivity of MDA-MB-231 Cancer Cell Line [PDF]
Iranian Journal of Medical Sciences, 2021 Background: Breast cancer is the second most common cancer in women worldwide. Developing drugs increase the radiosensitivity effect of tumoral tissue, while protecting normal tissues has gained much attention.
Vahid Changizi +2 more
doaj +1 more source
Foods, 2023 Ginsenoside Rg3 is reported to contribute to the traditionally known diverse effects of red ginseng extracts. Significant individual variations in the therapeutic efficacy of red ginseng extracts have been reported.
Jeon-Kyung Kim +5 more
doaj +1 more source
Two Ginseng UDP-Glycosyltransferases Synthesize Ginsenoside Rg3 and Rd [PDF]
Plant and Cell Physiology, 2014 Ginseng is a medicinal herb that requires cultivation under shade conditions, typically for 4-6 years, before harvesting. The principal components of ginseng are ginsenosides, glycosylated tetracyclic terpenes. Dammarene-type ginsenosides are classified into two groups, protopanaxadiol (PPD) and protopanaxatriol (PPT), based on their hydroxylation ...
Jung, SC Jung, Suk-Chae +10 more
openaire +3 more sources
Molecules, 2023 Ginsenoside Rg3, Rk1, and Rg5, rare ginsenosides from Panax ginseng, have many pharmacological effects, which have attracted extensive attention. They can be obtained through the heat treatment of Gynostemma pentaphyllum. In this study, scanning electron
Xin-Can Li +5 more
doaj +1 more source
Anticancer effects of ginsenoside Rg3 (Review)
International Journal of Molecular Medicine, 2017 Cancer is a life-threatening disease with an alarmingly increased annual mortality rate globally. Although various therapies are employed for cancer, the final effect is not satisfactory. Chemotherapy is currently the most commonly used treatment option.
Mengyao, Sun +5 more
openaire +3 more sources
Targeting Ferroptosis With Ginsenoside Rg3 Alleviates Intervertebral Disc Degeneration. [PDF]
Orthop SurgABSTRACTObjectiveIntervertebral disc degeneration (IVDD) has been closely associated with ferroptosis in nucleus pulposus cells (NPCs), the underlying regulatory mechanisms and therapeutic strategies remain poorly defined. This study aims to delineate how ginsenoside Rg3 mitigates IVDD progression through ferroptosis suppression, providing a basis for ...
Xu W, Geng F, Zhang K, Wang Y.
europepmc +3 more sources
Efficacy and safety of ginsam, a vinegar extract from Panax ginseng, in type 2 diabetic patients: Results of a double‐blind, placebo‐controlled study [PDF]
, 2014 Aims/Introduction: The efficacy, dose–response relationship and safety of ginsam, a vinegar extract from Panax ginseng, were evaluated in an 8‐week, double‐blind, randomized, placebo‐controlled study in drug‐naïve patients with type 2 diabetes. Materials
Ahn, Hwa Young +9 more
core +1 more source
Drug-mediated shortening of action potentials in LQTS2 hiPSC-cardiomyocytes [PDF]
, 2017 Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) are now a well-established modality for modeling genetic disorders of the heart.
Denning, Chris +6 more
core +3 more sources