Results 31 to 40 of about 8,812 (152)

The Content and Principle of the Rare Ginsenosides Produced from Gynostemma pentaphyllum after Heat Treatment

Molecules, 2023
Ginsenoside Rg3, Rk1, and Rg5, rare ginsenosides from Panax ginseng, have many pharmacological effects, which have attracted extensive attention. They can be obtained through the heat treatment of Gynostemma pentaphyllum. In this study, scanning electron
Xin-Can Li, Fang-Fang Li, Wen-Jing Pei, Jing Yang, Yu-Long Gu, Xiang-Lan Piao   +5 more
doaj   +1 more source

Ginsenoside Rg3 Protects against Diabetic Cardiomyopathy and Promotes Adiponectin Signaling via Activation of PPAR-γ

, 2023
Ginsenoside Rg3 extracted from Panax notoginseng has therapeutic effects on diabetes and heart diseases. However, the underlying mechanism of ginsenoside Rg3 on diabetic cardiomyopathy (DCM) remains unclear.
Chenyang Zhang, Huifang Yu, Jingxue Ye, Hongna Tong, Min Wang, Guibo Sun   +5 more
core   +1 more source

Ginsenoside RG3 inhibits epithelial-mesenchymal transition of gallbladder cancer cells through PI3K/AKT/mTOR signaling pathway [PDF]

Waike lilun yu shijian
Objective To explore the specific mechanism of Ginsenoside Rg3 inhibiting gallbladder cancer (GBC)cells. Methods Cell counting kit-8(CCK-8) assay was used to examine the effect of Ginsenoside Rg3 on the viability of GBC cells.
ZHOU Xin, WANG Lubing, ZHANG Bo
doaj   +1 more source

Ginsenoside rg3 reduces body weight by regulating fat content and browning in obese mice

Journal of Traditional Chinese Medical Sciences, 2021
Objective: To determine the effects of ginsenoside rg3 on the body weight of C57BL/6J obese mice and to investigate its underlying weight loss mechanisms with a focus on white fat browning-related factors.
Qianqian Mu, Jiacheng Zuo, Dandan Zhao, Xiaoshan Zhou, Jing Hua, Ying Bai, Fangfang Mo, Xin Fang, Min Fu, Sihua Gao   +9 more
doaj   +1 more source

Conversion of Protopanaxadiol Type Saponins to Ginsenoside Rg3 by Lemon

Natural Product Communications, 2012
The ability of fresh lemon ( Citrus limon ) to convert protopanaxadiol-type saponins into ginsenoside Rg3 was investigated, and the structures of 20( S )-ginsenoside Rg3 (1) and 20( R )-ginsenoside Rg3 (2) were identified by 1 H NMR and 13 C NMR ...
Cheng-Peng Sun, Wei-Ping Gao, Bao-Zhong Zhao, Le-Qin Cheng   +3 more
doaj   +1 more source

Pharmacological properties, molecular mechanisms and therapeutic potential of ginsenoside Rg3 as an antioxidant and anti-inflammatory agent

Frontiers in Pharmacology, 2022
Inflammation and oxidative stress lead to various acute or chronic diseases, including pneumonia, liver and kidney injury, cardiovascular and cerebrovascular diseases, metabolic diseases, and cancer.
Jing Wang, Jing Wang, Li Zeng, Ying Zhang, Wenxiu Qi, Ziyuan Wang, Lin Tian, Daqing Zhao, Qibiao Wu, Qibiao Wu, Xiangyan Li, Tan Wang   +11 more
doaj   +1 more source

Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway

, 2020
Inflammation and autophagy occur during hepatic fibrosis development caused by various pathogens, and effectively curbing of autophage may delay the occurrence of hepatic fibrosis.
Jiang, Shuang, Wang, Zi, Hou, Jingang, Chen, Chen, Wang, Yingping, Liu, Xiangxiang, Li, Wei, Mi, Xiaojie, Zhang, Ming   +8 more
core   +1 more source

Evaluation of the gastroprotective effects of 20 (S)-ginsenoside Rg3 on gastric ulcer models in mice

Journal of Ginseng Research, 2019
Background: Gastric ulcer (GU) is a common gastrointestinal disease that can be induced by many factors. Finding an effective treatment method that contains fewer side effects is important.
Kai Zhang, Ying Liu, Cuizhu Wang, Jiannan Li, Lingxin Xiong, Zhenzhou Wang, Jinping Liu, Pingya Li   +7 more
doaj   +1 more source

Ginsenoside RG3 Synergizes With STING Agonist to Reverse Cisplatin Resistance in Gastric Cancer. [PDF]

Food Sci Nutr
This study investigates the synergistic inhibitory effects of combining the stimulator of interferon genes (STING) agonist cyclic diadenylate monophosphate (c-di-AMP) and ginsenoside RG3 on cisplatin (DDP)-resistant gastric cancer (GC) cells.
Lu Z, Fu Y, Fu Q, Chang Y, Zhang M, Jin T.   +5 more
europepmc   +2 more sources

Ginsenoside Rg3 inhibits the biological activity of SGC‐7901

, 2020
AIM To explore the suppressive effects of ginsenoside Rg3 on the biological activities of gastric cancer and the mechanisms responsible therein, by conducting an in vitro study.
Qing Yang, Xing Chen, Che, Daobiao, Wang, Dongliang, Dongliang Wang, Ning Cai, Daobiao Che, Cai, Ning, Chen, Xing, Yang, Qing   +9 more
core   +1 more source