Results 11 to 20 of about 4,514 (169)

Conversion of Protopanaxadiol Type Saponins to Ginsenoside Rg3 by Lemon [PDF]

Natural Product Communications, 2012
The ability of fresh lemon ( Citrus limon ) to convert protopanaxadiol-type saponins into ginsenoside Rg3 was investigated, and the structures of 20( S )-ginsenoside Rg3 (1) and 20( R )-ginsenoside Rg3 (2) were identified by 1 H NMR and 13 C NMR ...
Cheng-Peng Sun, Wei-Ping Gao, Bao-Zhong Zhao, Le-Qin Cheng   +3 more
doaj   +3 more sources

Ginsenoside Rg3 hydrogel in gastric cancer therapy

Nano Research
Gastric cancer is a major global health challenge, associated with high mortality and limited therapeutic options. Ginsenoside Rg3 (Rg3), a bioactive compound derived from ginseng, has been shown to possess significant anticancer properties, particularly
Fangbin Zhang, Yan Yan, Xinguang Cao, Jinping Zhang, Yingxia Li, Changqing Guo   +5 more
doaj   +2 more sources

Network Analysis of 20S-Ginsenoside Rg3 Effect on Human Colorectal Adenocarcinoma Cell Line HT-29 [PDF]

Research Journal of Pharmacognosy, 2022
Background and objectives: 20S-Ginsenoside Rg3 is a pharmacological active compound of ginseng. Evidences indicate that S20-Rg3 as an anti-cancer factor plays role in prevention and treatment of cancer.
Mona Zamanian Azodi, Babak Arjmand, Mostafa Rezaei Tavirani*, Mahmood Khodadoost, Mohammad Rostami Nejad, Nayebali Ahmadi   +5 more
doaj   +1 more source

Polymer-Based Wound Dressings Loaded with Ginsenoside Rg3. [PDF]

Molecules, 2023
The skin, the largest organ in the human body, mainly plays a protective role. Once damaged, it can lead to acute or chronic wounds. Wound healing involves a series of complex physiological processes that require ideal wound dressings to promote it.
Yang J, Zhang L, Peng X, Zhang S, Sun S, Ding Q, Ding C, Liu W.   +7 more
europepmc   +4 more sources

Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway

Journal of Ginseng Research, 2022
Background: Ginsenoside Rg3 is one of the main active ingredients in ginseng. Here, we aimed to confirm its protective effect on the heart function in transverse aortic coarctation (TAC)-induced heart failure mice and explore the potential molecular ...
Jingyu Ni, Zhihao Liu, Miaomiao Jiang, Lan Li, Jie Deng, Xiaodan Wang, Jing Su, Yan Zhu, Feng He, Jingyuan Mao, Xiumei Gao, Guanwei Fan   +11 more
doaj   +1 more source

Ginsenoside Rg3 attenuates fat accumulation in zebrafish with high-fat-diet-induced obesity

Pharmacological Research - Modern Chinese Medicine, 2022
Ginsenoside Rg3 is one of major steroidal saponins in Panax ginseng that has demonstrated several therapeutic effects. In this study, we investigated the effects of ginsenoside Rg3 on lipid accumulation in a high-fat diet (HFD) larval zebrafish model by ...
Fei Li, Xin Sui, Renwen Zhang, Qiuting Huang, Ying Xie   +4 more
doaj   +1 more source

Ginsenoside Rg3 Alleviates Cisplatin Resistance of Gastric Cancer Cells Through Inhibiting SOX2 and the PI3K/Akt/mTOR Signaling Axis by Up-Regulating miR-429

Frontiers in Genetics, 2022
Platinum-based cytotoxic chemotherapy is considered the standard treatment for advanced gastric cancer (GC). However, cisplatin chemoresistance often occurs with the mechanisms being not well clarified, which results in the cancer recurrence and poor ...
Xiaofeng Wang, Rui He, Li Geng, Jing Yuan, Huijie Fan   +4 more
doaj   +1 more source

Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization

Journal of Ginseng Research, 2022
Background: Ginsenoside Rg3 and gemcitabine have mutual enhancing antitumor effects. However, the underlying mechanisms are not clear. This study explored the influence of ginsenoside Rg3 on Zinc finger protein 91 homolog (ZFP91) expression in pancreatic
Haixia Pan, Linhan Yang, Hansong Bai, Jing Luo, Ying Deng   +4 more
doaj   +1 more source

Pharmacokinetic Profiling of Ginsenosides, Rb1, Rd, and Rg3, in Mice with Antibiotic-Induced Gut Microbiota Alterations: Implications for Variability in the Therapeutic Efficacy of Red Ginseng Extracts

Foods, 2023
Ginsenoside Rg3 is reported to contribute to the traditionally known diverse effects of red ginseng extracts. Significant individual variations in the therapeutic efficacy of red ginseng extracts have been reported.
Jeon-Kyung Kim, Min Sun Choi, Hee-Seo Park, Kyung Hwa Kee, Dong-Hyun Kim, Hye Hyun Yoo   +5 more
doaj   +1 more source

Co-treatment with Ginsenoside 20(S)-Rg3 and Curcumin increases Radiosensitivity of MDA-MB-231 Cancer Cell Line [PDF]

Iranian Journal of Medical Sciences, 2021
Background: Breast cancer is the second most common cancer in women worldwide. Developing drugs increase the radiosensitivity effect of tumoral tissue, while protecting normal tissues has gained much attention.
Vahid Changizi, Vahideh Gharekhani, Elaheh Motavaseli   +2 more
doaj   +1 more source