Results 21 to 30 of about 4,514 (169)

Ginsenoside Rg3 inhibits the biological activity of SGC‐7901 [PDF]

open access: yesFood Science & Nutrition, 2020
AbstractAimTo explore the suppressive effects of ginsenoside Rg3 on the biological activities of gastric cancer and the mechanisms responsible therein, by conducting an in vitro study.Materials and MethodsSGC‐7901 gastric cancer cells were divided into NC, DMSO, Gin‐Low (10 mg/L), Gin‐Middle (20 mg/L), and Gin‐High (40 mg/L) groups.
Qing Yang   +4 more
openaire   +2 more sources

Conjugation of Ginsenoside Rg3 with Gold Nanoparticles [PDF]

open access: yesBulletin of the Korean Chemical Society, 2011
Ginsenoside Rg3 was reported to have important biological activities. We demonstrate conjugation and quantification procedures of ginsenoside Rg3 to gold nanoparticles for future biological and medical applications. Ginsenoside Rg3 was conjugated to spherical gold nanoparticles using a bifunctional heptaethylene glycol linker.
You-Mie Park   +7 more
openaire   +1 more source

The Content and Principle of the Rare Ginsenosides Produced from Gynostemma pentaphyllum after Heat Treatment

open access: yesMolecules, 2023
Ginsenoside Rg3, Rk1, and Rg5, rare ginsenosides from Panax ginseng, have many pharmacological effects, which have attracted extensive attention. They can be obtained through the heat treatment of Gynostemma pentaphyllum. In this study, scanning electron
Xin-Can Li   +5 more
doaj   +1 more source

Acute and repeated dose 26-week oral toxicity study of 20(S)-ginsenoside Rg3 in Kunming mice and Sprague–Dawley rats

open access: yesJournal of Ginseng Research, 2020
Background: 20(S)-ginsenoside-Rg3 (C42H72O13), a natural triterpenoid saponin, is extracted from red ginseng. The increasing use of 20(S)-ginsenoside Rg3 has raised product safety concerns. Methods: In acute toxicity, 20(S)-ginsenoside Rg3 was singly and
Chunmei Li   +12 more
doaj   +1 more source

Anticancer effects of ginsenoside Rg3 (Review)

open access: yesInternational Journal of Molecular Medicine, 2017
Cancer is a life-threatening disease with an alarmingly increased annual mortality rate globally. Although various therapies are employed for cancer, the final effect is not satisfactory. Chemotherapy is currently the most commonly used treatment option.
Mengyao, Sun   +5 more
openaire   +3 more sources

Ginsenoside RG3 inhibits epithelial-mesenchymal transition of gallbladder cancer cells through PI3K/AKT/mTOR signaling pathway [PDF]

open access: yesWaike lilun yu shijian
Objective To explore the specific mechanism of Ginsenoside Rg3 inhibiting gallbladder cancer (GBC)cells. Methods Cell counting kit-8(CCK-8) assay was used to examine the effect of Ginsenoside Rg3 on the viability of GBC cells.
ZHOU Xin, WANG Lubing, ZHANG Bo
doaj   +1 more source

Ginsenoside rg3 reduces body weight by regulating fat content and browning in obese mice

open access: yesJournal of Traditional Chinese Medical Sciences, 2021
Objective: To determine the effects of ginsenoside rg3 on the body weight of C57BL/6J obese mice and to investigate its underlying weight loss mechanisms with a focus on white fat browning-related factors.
Qianqian Mu   +9 more
doaj   +1 more source

Ginsenoside Rg3 Promotes Cell Growth Through Activation of mTORC1 [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Graphical AbstractGinsenoside Rg3 promotes cell growth through activation of mTORC1 and increasing mitochondrial biogenesis.
Wei Liu   +13 more
openaire   +3 more sources

Generation and Characterization of Monoclonal Antibody to Ginsenoside Rg3

open access: yesBiological and Pharmaceutical Bulletin, 2009
While studying the mechanism of ginsenoside Rg3 (G-Rg3) on tumor inhibition, we produced monoclonal antibody to G-Rg3 for more specific investigation. We immunized Balb/c mice to G-Rg3 conjugated bovine serum albumin (BSA) by intraperitoneal injection and hybridized splenocytes from those immunized mice and myeloma cells.
Joo, Eun Ji   +4 more
openaire   +3 more sources

Preparation of Ginsenoside Rg3 and Protection against H2O2-Induced Oxidative Stress in Human Neuroblastoma SK-N-SH Cells

open access: yesJournal of Chemistry, 2014
The aim of this study is to evaluate the protection of ginsenoside Rg3 against oxidative stress in human neuroblastoma SK-N-SH cells. 20(R)-ginsenoside Rg3 (20(R)-Rg3) and 20(S)-ginsenoside Rg3 (20(S)-Rg3) were prepared by the method of chemical ...
Gang Li   +6 more
doaj   +1 more source

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