Results 21 to 30 of about 6,327 (215)

Protective effects of 20(R) ginsenoside Rg3 on DBP-induced reproductive injury in mice through Nrf2/ARE pathway [PDF]

Scientific Reports
Di-n-butyl phthalate (DBP), an environmental endocrine disruptor, can induce male reproductive dysfunction. In the study, the protective mechanism of ginsenoside Rg3 (Rg3) against DBP-induced damage to spermatogenic function was explored through the Nrf2/
Huan Li, Hongyan Wang, Lan lan, Xinyan Luo, Jing Zhang, Li Qu   +5 more
doaj   +2 more sources

Ginsenoside Rg3 inhibits pulmonary fibrosis by preventing HIF-1α nuclear localisation [PDF]

BMC Pulmonary Medicine, 2021
Background Excessive fibroblast proliferation during pulmonary fibrosis leads to structural abnormalities in lung tissue and causes hypoxia and cell injury. However, the mechanisms and effective treatment are still limited.
Zhuo Fu, Yong-sheng Xu, Chun-quan Cai
doaj   +3 more sources

Ginsenoside Rg3 Ameliorates Psoriasis-Like Dermatitis through Inhibition of NF-κB/NLRP3 Inflammasome Signaling and Regulating Th17/Treg Balance. [PDF]

Immun Inflamm Dis
ABSTRACT Background Psoriasis, characterized as a persistent cutaneous inflammatory condition driven by aberrant immunity, exhibits pathogenesis and disease course heavily influenced by sustained inflammatory activity. Ginsenoside Rg3 (Grg3), a traditional Chinese medicinal compound, has shown notable therapeutic effects on various inflammatory ...
Gao L, Xie Q, Zhou Z, Zhang W, Sun H, Yue Z, Jiang C.   +6 more
europepmc   +2 more sources

Network Analysis of 20S-Ginsenoside Rg3 Effect on Human Colorectal Adenocarcinoma Cell Line HT-29 [PDF]

Research Journal of Pharmacognosy, 2022
Background and objectives: 20S-Ginsenoside Rg3 is a pharmacological active compound of ginseng. Evidences indicate that S20-Rg3 as an anti-cancer factor plays role in prevention and treatment of cancer.
Mona Zamanian Azodi, Babak Arjmand, Mostafa Rezaei Tavirani*, Mahmood Khodadoost, Mohammad Rostami Nejad, Nayebali Ahmadi   +5 more
doaj   +1 more source

Relationship Between Ginsenoside Rg3 and Metabolic Syndrome [PDF]

Frontiers in Pharmacology, 2020
Metabolic syndrome is an important public health issue and is associated with a more affluent lifestyle. Many studies of metabolic syndrome have been reported, but its pathogenesis remains unclear and there is no effective treatment. The ability of natural compounds to ameliorate metabolic syndrome is currently under investigation.
Hyunji Lee, Hyunji Lee, Gyeyeong Kong, Gyeyeong Kong, Quangdon Tran, Quangdon Tran, Chaeyeong Kim, Chaeyeong Kim, Jisoo Park, Jisoo Park, Jisoo Park, Jongsun Park, Jongsun Park   +12 more
openaire   +3 more sources

Ginsenoside Rg3 Promotes Cell Growth Through Activation of mTORC1 [PDF]

Frontiers in Cell and Developmental Biology, 2021
Graphical AbstractGinsenoside Rg3 promotes cell growth through activation of mTORC1 and increasing mitochondrial biogenesis.
Wei Liu, Wei Liu, Sheng-Xiong Zhang, Bo Ai, Hua-Feng Pan, Dan Zhang, Yu Jiang, Lei-Hao Hu, Lei-Hao Hu, Ling-Ling Sun, Ling-Ling Sun, Zhe-Sheng Chen, Li-Zhu Lin, Li-Zhu Lin   +13 more
openaire   +3 more sources

Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway

Journal of Ginseng Research, 2022
Background: Ginsenoside Rg3 is one of the main active ingredients in ginseng. Here, we aimed to confirm its protective effect on the heart function in transverse aortic coarctation (TAC)-induced heart failure mice and explore the potential molecular ...
Jingyu Ni, Zhihao Liu, Miaomiao Jiang, Lan Li, Jie Deng, Xiaodan Wang, Jing Su, Yan Zhu, Feng He, Jingyuan Mao, Xiumei Gao, Guanwei Fan   +11 more
doaj   +1 more source

Ginsenoside Rg3 inhibits the biological activity of SGC‐7901 [PDF]

Food Science & Nutrition, 2020
AbstractAimTo explore the suppressive effects of ginsenoside Rg3 on the biological activities of gastric cancer and the mechanisms responsible therein, by conducting an in vitro study.Materials and MethodsSGC‐7901 gastric cancer cells were divided into NC, DMSO, Gin‐Low (10 mg/L), Gin‐Middle (20 mg/L), and Gin‐High (40 mg/L) groups.
Qing Yang, Ning Cai, Daobiao Che, Xing Chen, Dongliang Wang   +4 more
openaire   +3 more sources

Ginsenoside Rg3 attenuates fat accumulation in zebrafish with high-fat-diet-induced obesity

Pharmacological Research - Modern Chinese Medicine, 2022
Ginsenoside Rg3 is one of major steroidal saponins in Panax ginseng that has demonstrated several therapeutic effects. In this study, we investigated the effects of ginsenoside Rg3 on lipid accumulation in a high-fat diet (HFD) larval zebrafish model by ...
Fei Li, Xin Sui, Renwen Zhang, Qiuting Huang, Ying Xie   +4 more
doaj   +1 more source

Polymer-Based Wound Dressings Loaded with Ginsenoside Rg3

Molecules, 2023
The skin, the largest organ in the human body, mainly plays a protective role. Once damaged, it can lead to acute or chronic wounds. Wound healing involves a series of complex physiological processes that require ideal wound dressings to promote it.
Jiali Yang, Lifeng Zhang, Xiaojuan Peng, Shuai Zhang, Shuwen Sun, Qiteng Ding, Chuanbo Ding, Wencong Liu   +7 more
openaire   +3 more sources