Results 71 to 80 of about 4,987 (188)

Two Ginseng UDP-Glycosyltransferases Synthesize Ginsenoside Rg3 and Rd [PDF]

Plant and Cell Physiology, 2014
Ginseng is a medicinal herb that requires cultivation under shade conditions, typically for 4-6 years, before harvesting. The principal components of ginseng are ginsenosides, glycosylated tetracyclic terpenes. Dammarene-type ginsenosides are classified into two groups, protopanaxadiol (PPD) and protopanaxatriol (PPT), based on their hydroxylation ...
Jung, SC Jung, Suk-Chae, Kim, W Kim, Woohyun, Park, SC Park, Sung Chul, Jeong, J Jeong, Jinkil, Park, MK Park, Myung Keun, Lim, S Lim, Soohwan, Lee, Y Lee, Yeon, Im, WT Im, Wan-Taek, Lee, JH Lee, Jun Hyoung, Choi, GT Choi, Gil-Tsu, Kim, SC Kim, Sun Chang   +10 more
openaire   +3 more sources

Chromosome‐Level Genome Assembly of the Allotetraploid Gynostemma pentaphyllum Provides Novel Insights Into the Biosynthesis of Ginsenoside and Gypenoside LVI

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4204-4220, June 2026.
ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou, Si‐Jie Liu, Lijin Huang, Yingping Wang, Xinyu Jiang, Wang Dong, Jianfeng Gong, Long Wang, Yuyin Zhao, Huiying Wang, Ping Li, Jia‐Yu Xue, Xu Lu   +12 more
wiley   +1 more source

20(R)-ginsenoside Rg3, a rare saponin from red ginseng, ameliorates acetaminophen-induced hepatotoxicity by suppressing PI3K/AKT pathway-mediated inflammation and apoptosis

, 2018
Although ginsenoside Rg3 was isolated as a major component of Korea red ginseng and confirmed to exert potential hepatoprotective effect on acetaminophen (APAP)-induced liver injury via induction of glutathione S-transferase (GST) in vitro, thein vivo ...
Ren, Shen, Liu, Wei, Li, Wei, Hou, Jin-gang, Ying-ping Wang, Chen Chen, Rui Zhang, Zhou, Yan-dan, Wang, Zi, Chen, Chen, Wei Li, Shen Ren, Zhang, Rui, Jin-gang Hou, Wei Liu, Zi Wang, Wang, Ying-ping, Yan-dan Zhou   +17 more
core   +1 more source

DataSheet1_Poloxamer 407 and Hyaluronic Acid Thermosensitive Hydrogel-Encapsulated Ginsenoside Rg3 to Promote Skin Wound Healing.docx

, 2022
Ginsenoside Rg3 has shown beneficial effects in various skin diseases. The current interest in designing and developing hydrogels for biomedical applications continues to grow, inspiring the further development of drug-loaded hydrogels for tissue repair ...
Xiaojuan Peng (559395), Wencong Liu (8474718), Yinan Zheng (738069), Chuanbo Ding (12879746), Mingqian Hao (12879743), Min Yang (146229), Fengyan Xiao (7305827), Yingchun Zhao (295903)   +7 more
core   +1 more source

The Efficacy of Ginsenoside Rg3 Combined with First-line Chemotherapy in the Treatment of Advanced Non-Small Cell Lung Cancer in China: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Frontiers in Pharmacology, 2021
Background: For advanced non-small cell lung cancer (NSCLC) patients, first-line chemotherapy is the main treatment in the clinic despite its efficacy is limited and adverse effects are always inescapable.
Ze Peng, Wen Wen Wu, Ping Yi
doaj   +1 more source

Emerging Role of Panax ginseng in the Management of Cancer: Phytochemistry, SAR, Therapeutic Potential, and Clinical Aspects

Food Frontiers, Volume 7, Issue 3, May 2026.
This review aims to provide a comprehensive understanding of the therapeutic potential of bioactive anticancer phytoconstituents in Panax ginseng, including their clinical aspects and SAR, thereby fostering the development of newer anticancer compounds for cancer management.
Akrit Verma, Sanjeev Kumar Sahu, Anil Kumar Sah   +2 more
wiley   +1 more source

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

Advanced Science, Volume 13, Issue 19, 2 April 2026.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang, Wen Zhou, Haotian Xue, Wenjun Xue, Guangping Gao, Bing Zhu, Hongyuan Song, Qingqiang Xu, Jing Zhao, Wei Shen   +9 more
wiley   +1 more source

Data for: Ginsenoside Rg3 reduces the adhesion, invasion and intracellular survival of Salmonella enterica serovar Typhimurium

, 2019
The data is collected from in vitro studies on the preventive effects of ginsenoside Rg3 on the adhesion, invasion, and intracellular survival of Salmonella Typhimurium in intestinal epithelial cells and macrophages.
Park, S
core   +2 more sources

Pharmacological Inhibition of APT2 by Solasonine Promotes Ferroptosis Through Palmitoylation Modulation in Gallbladder Cancer

Phytotherapy Research, Volume 40, Issue 4, Page 1642-1660, April 2026.
Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi, Jing‐wei Zhao, Jia‐yun Zhu, Cheng Zhao, Zi‐yi Yang, Li‐jia Pan, Ben Ma, Zheng‐yu Chen, Zi‐ying Wang, Chun‐jie Li, Shi‐lei Liu, Jia‐wei Mei, Ping Dong   +12 more
wiley   +1 more source

Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions

Journal of Ginseng Research, 2018
Ginseng has gained its popularity as an adaptogen since ancient days because of its triterpenoid saponins, known as ginsenosides. These triterpenoid saponins are unique and classified as protopanaxatriol and protopanaxadiol saponins based on their glycosylation patterns.
Padmanaban Mohanan, Sathiyamoorthy Subramaniyam, Ramya Mathiyalagan, Deok-Chun Yang   +3 more
openaire   +3 more sources