The protective effect of 20(S)-ginsenoside Rg3 on the human retinal pigment epithelial cells against hydrogen peroxide-induced oxidative stress. [PDF]
Food Sci BiotechnolKim BK, Kim KU, Kim J, Jang H, Min H.
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Ginsenoside Rg3 induces mesangial cells proliferation and attenuates apoptosis by miR-216a-5p/MAPK pathway in diabetic kidney disease. [PDF]
Aging (Albany NY)Chen Y, Peng Y, Li P, Jiang Y, Song D.
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Ginsenoside Rg3, enriched in red ginseng extract, improves lipopolysaccharides-induced suppression of brown and beige adipose thermogenesis with mitochondrial activation. [PDF]
Sci RepFeng F +5 more
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International Journal of Molecular Sciences, 2012 Cardiovascular disease (CVD) is one of the main causes of mortality worldwide, and dyslipidemia is a major risk factor for CVD. Ginseng has been widely used in the clinic to treat CVD.
Seohyun Lee +2 more
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Insights into the antitumor mechanism of ginsenosides Rg3
Molecular Biology Reports, 2021Panax ginseng, an ancient herb, belonging to Chinese traditional medicine, is an important herb that has a remarkable impact on various diseases. Ginsenoside Rg3, one of the most abundant ginsenosides, exerts significant functions in the prevention of various types of cancers with few side effects.
Zongyu Liu +5 more
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Therapeutic potential of ginsenoside Rg3 and Rf for Huntington’s disease
In Vitro Cellular & Developmental Biology - Animal, 2021Ginseng is a popular herbal medicine and known to have protective and therapeutic effects in various diseases. Ginsenosides are active gradients representing the diverse pharmacological efficacy of ginseng. Huntington's disease (HD) is incurable genetic disorder associated with mutant huntingtin (mHtt) aggregation in the central nervous system.
Mijung, Lee +4 more
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Conversion of major ginsenoside Rb1 to 20(S)-ginsenoside Rg3 by Microbacterium sp. GS514
Phytochemistry, 2008Ginseng saponin, the most important secondary metabolite in ginseng, has various pharmacological activities. Many studies have been directed towards converting major ginsenosides to the more active minor ginsenoside, Rg3. Due to the difficulty in preparing ginsenoside Rg3 enzymatically, the compound has been mainly produced by either acid treatment or ...
Myung Kyum Kim, Deok-Chun Yang
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Preparation and bioactivity of the rare ginsenosides Rg3 and Rh2: An updated review
Fitoterapia, 2023Ginseng, an ancient medicinal herb, is used in oriental medicine for the treatment of various diseases. Saponins are the main bioactive components of ginseng, but the multiple glucosyl side chains on its molecules prevent ginsenosides from entering the blood through the intestinal membrane, thus reducing the efficacy.
Wenqi, Xu +5 more
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The angiosuppressive effects of 20(R)- ginsenoside Rg3
Biochemical Pharmacology, 2006Aberrant angiogenesis is an essential step for the progression of solid tumors. Thus anti-angiogenic therapy is one of the most promising approaches to control tumor growth. In this study, we examined the ability of 20(R)-ginsenoside Rg3 (Rg3), one of the active compounds present in ginseng root, to interfere with the various steps of angiogenesis. Rg3
Patrick Y K, Yue +10 more
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