Results 1 to 10 of about 16,039 (141)

Production of Minor Ginsenoside CK from Major Ginsenosides by Biotransformation and Its Advances in Targeted Delivery to Tumor Tissues Using Nanoformulations

Nanomaterials, 2022
For over 2000 years, ginseng (roots of Panax ginseng C.A. Meyer) has been used as a traditional herbal medicine. Ginsenosides are bioactive compounds present in ginseng responsible for the pharmacological effects and curing various acute diseases as well
Mohanapriya Murugesan, Ramya Mathiyalagan, Vinothini Boopathi, Byoung Man Kong, Sung-Keun Choi, Chang-Soon Lee, Deok Chun Yang, Se Chan Kang, Thavasyappan Thambi   +8 more
doaj   +2 more sources

Advances in Ginsenosides [PDF]

Biomolecules, 2020
Ginsenosides are unique to plants that belong to the Panax genus [...]
J. Chen
openaire   +4 more sources

Thermal transformation of polar into less-polar ginsenosides through demalonylation and deglycosylation in extracts from ginseng pulp

Scientific Reports, 2021
The present study was conducted to qualitatively and quantitatively elucidate dynamic changes of ginsenosides in ginseng pulp steamed under different temperatures (100 or 120 °C) for different durations (1–6 h) through UPLC-QTOF-MS/MS and HPLC with the ...
Fan Yao, Xiang Li, Jing Sun, Xinxin Cao, Mengmeng Liu, Yuanhang Li, Yujun Liu   +6 more
doaj   +2 more sources

Pharmacological effects of natural medicine ginsenosides against Alzheimer’s disease

Frontiers in Pharmacology, 2022
Ginsenosides are the most important pharmacological active ingredient of ginseng, with multiple biological therapeutic targets, mild action and no side effects. It is having shown beneficial effects in vitro and in vivo models of AD.
Zhikun Shi, Hongyu Chen, Xu Zhou, Wei Yang, Yang Lin   +4 more
doaj   +2 more sources

Effect of Lactic Acid Bacteria on the Pharmacokinetics and Metabolism of Ginsenosides in Mice

Pharmaceutics, 2021
This study aims to investigate the effect of lactic acid bacteria (LAB) on in vitro and in vivo metabolism and the pharmacokinetics of ginsenosides in mice.
Ji-Hyeon Jeon, Jaehyeok Lee, Jin-Hyang Park, Chul-Haeng Lee, Min-Koo Choi, Im-Sook Song   +5 more
doaj   +2 more sources

Detection of 13 Ginsenosides (Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg3, Rh2, F1, Compound K, 20(S)-Protopanaxadiol, and 20(S)-Protopanaxatriol) in Human Plasma and Application of the Analytical Method to Human Pharmacokinetic Studies Following Two Week-Repeated Administration of Red Ginseng Extract

Molecules, 2019
We aimed to develop a sensitive method for detecting 13 ginsenosides using liquid chromatography−tandem mass spectrometry and to apply this method to pharmacokinetic studies in human following repeated oral administration of red ginseng extract ...
Sojeong Jin, Ji-Hyeon Jeon, Sowon Lee, Woo Youl Kang, Sook Jin Seong, Young-Ran Yoon, Min-Koo Choi, Im-Sook Song   +7 more
doaj   +2 more sources

Effects of ginsenosides on bone remodelling for novel drug applications: a review

Chinese Medicine, 2020
Background Ginsenosides are pharmacologically active compounds that are often extracted from the Panax plant for their medicinal properties. Ginsenosides have multiple effects, including antitumor effects which have been widely studied.
Nan Yang, Dingkun Liu, Xiao Zhang, Jianing Li, Mi Wang, Tongtong Xu, Zhihui Liu   +6 more
doaj   +2 more sources

Research Progress on the Biotransformation of Rare Ginsenosides

Shipin gongye ke-ji, 2023
As the main active component in ginseng, ginsenoside is widely used in food and medicine. Ginsenosides have different properties and functions due to their different chemical structures.
Songzhu YUAN, Bin WANG, Xuan ZHOU, Shengming ZHAO, Yi WANG, Jun LEI, Ping CHEN   +6 more
doaj   +1 more source

Ginsenosides from Panax ginseng as Key Modulators of NF-κB Signaling Are Powerful Anti-Inflammatory and Anticancer Agents

International Journal of Molecular Sciences, 2023
Nuclear factor kappa B (NF-κB) signaling pathways progress inflammation and immune cell differentiation in the host immune response; however, the uncontrollable stimulation of NF-κB signaling is responsible for several inflammatory illnesses regardless ...
Won Young Jang, Ji-yeon Hwang, J. Cho
semanticscholar   +1 more source

β-Glucosidase and Its Application in Bioconversion of Ginsenosides in Panax ginseng

Bioengineering, 2023
Ginsenosides are a group of bioactive compounds isolated from Panax ginseng. Conventional major ginsenosides have a long history of use in traditional medicine for both illness prevention and therapy.
Thi Ngoc Anh Tran, Jin‐Sung Son, M. Awais, J. Ko, D. Yang, Seok-Kyu Jung   +5 more
semanticscholar   +1 more source