Results 1 to 10 of about 25,297 (234)

Methods on improvements of the poor oral bioavailability of ginsenosides: Pre-processing, structural modification, drug combination, and micro- or nano- delivery system

Journal of Ginseng Research, 2023
Panax ginseng Meyer is a traditional Chinese medicine that is widely used as tonic in Asia. The main pharmacologically active components of ginseng are the dammarane-type ginsenosides, which have been shown to have anti-cancer, anti-inflammatory ...
Qi-rui Hu, Huan Hong, Zhi-hong Zhang, Hua Feng, Ting Luo, Jing Li, Ze-yuan Deng, Fang Chen   +7 more
doaj   +2 more sources

Production of Minor Ginsenoside CK from Major Ginsenosides by Biotransformation and Its Advances in Targeted Delivery to Tumor Tissues Using Nanoformulations

Nanomaterials, 2022
For over 2000 years, ginseng (roots of Panax ginseng C.A. Meyer) has been used as a traditional herbal medicine. Ginsenosides are bioactive compounds present in ginseng responsible for the pharmacological effects and curing various acute diseases as well
Mohanapriya Murugesan, Ramya Mathiyalagan, Vinothini Boopathi, Byoung Man Kong, Sung-Keun Choi, Chang-Soon Lee, Deok Chun Yang, Se Chan Kang, Thavasyappan Thambi   +8 more
doaj   +2 more sources

Ginsenosides are active ingredients in Panax ginseng with immunomodulatory properties from cellular to organismal levels

Journal of Ginseng Research, 2022
The immune system is one of the most important parts of the human body and immunomodulation is the major function of the immune system. In response to outside pathogens or high inflammation, the immune system is stimulated or suppressed.
Long You, Seunghwa Cha, Mi-Yeon Kim, Jae Youl Cho   +3 more
doaj   +2 more sources

Pharmacological effects of natural medicine ginsenosides against Alzheimer’s disease

Frontiers in Pharmacology, 2022
Ginsenosides are the most important pharmacological active ingredient of ginseng, with multiple biological therapeutic targets, mild action and no side effects. It is having shown beneficial effects in vitro and in vivo models of AD.
Zhikun Shi, Hongyu Chen, Xu Zhou, Wei Yang, Yang Lin   +4 more
doaj   +2 more sources

Detection of 13 Ginsenosides (Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg3, Rh2, F1, Compound K, 20(S)-Protopanaxadiol, and 20(S)-Protopanaxatriol) in Human Plasma and Application of the Analytical Method to Human Pharmacokinetic Studies Following Two Week-Repeated Administration of Red Ginseng Extract

Molecules, 2019
We aimed to develop a sensitive method for detecting 13 ginsenosides using liquid chromatography−tandem mass spectrometry and to apply this method to pharmacokinetic studies in human following repeated oral administration of red ginseng extract ...
Sojeong Jin, Ji-Hyeon Jeon, Sowon Lee, Woo Youl Kang, Sook Jin Seong, Young-Ran Yoon, Min-Koo Choi, Im-Sook Song   +7 more
doaj   +2 more sources

Research Progress on the Biotransformation of Rare Ginsenosides

Shipin gongye ke-ji, 2023
As the main active component in ginseng, ginsenoside is widely used in food and medicine. Ginsenosides have different properties and functions due to their different chemical structures.
Songzhu YUAN, Bin WANG, Xuan ZHOU, Shengming ZHAO, Yi WANG, Jun LEI, Ping CHEN   +6 more
doaj   +1 more source

Ginsenosides in Panax genus and their biosynthesis

Acta Pharmaceutica Sinica B, 2021
Ginsenosides are a series of glycosylated triterpenoids which belong to protopanaxadiol (PPD)-, protopanaxatriol (PPT)-, ocotillol (OCT)- and oleanane (OA)-type saponins known as active compounds of Panax genus. They are accumulated in plant roots, stems,
M. Hou, Rufeng Wang, Shujuan Zhao, Zhengtao Wang   +3 more
semanticscholar   +1 more source

Ginsenosides from Panax ginseng as Key Modulators of NF-κB Signaling Are Powerful Anti-Inflammatory and Anticancer Agents

International Journal of Molecular Sciences, 2023
Nuclear factor kappa B (NF-κB) signaling pathways progress inflammation and immune cell differentiation in the host immune response; however, the uncontrollable stimulation of NF-κB signaling is responsible for several inflammatory illnesses regardless ...
W. Jang, Ji-yeon Hwang, J. Cho
semanticscholar   +1 more source

Comprehensive Identification of Ginsenosides in the Roots and Rhizomes of Panax ginseng Based on Their Molecular Features-Oriented Precursor Ions Selection and Targeted MS/MS Analysis

Molecules, 2023
Panax ginseng is widely used in Asian countries and its active constituents—ginsenosides—need to be systematically studied. However, only a small part of ginsenosides have been characterized in the roots and rhizomes of panax ginseng (RRPG) up to date ...
Hong-Ping Wang, Zi-Jian Wang, Jing Du, Zhao-Zhou Lin, Chen Zhao, Run Zhang, Qiong Yin, Chun-Lan Fan, Ping Peng, Zhi-Bin Wang   +9 more
doaj   +1 more source

Ginsenosides for therapeutically targeting inflammation through modulation of oxidative stress.

International Immunopharmacology, 2023
Ginsenosides are steroid glycosides derived from ginseng plants such as Panax ginseng, Panax quinquefolium, and Panax notoginseng. Advances in recent studies have identified numerous physiological functions of each type of ginsenoside, i.e ...
Seungwha Paik, G. Song, E. Jo
semanticscholar   +1 more source