Results 21 to 30 of about 15,696 (249)

Transformation of Ginsenosides by Lactiplantibacillus plantarum MB11 Fermentation: Minor Ginsenosides Conversion and Enhancement of Anti-Colorectal Cancer Activity

Molecules, 2023
The present study aimed to increase the content of minor ginsenosides and enhance the anti-colorectal cancer activity of ginsenosides via biotransformation by Lactiplantibacillus plantarum MB11 screened from fermented foods.
Yunjiao Shen, Yansong Gao, Ge Yang, Zijian Zhao, Yujuan Zhao, Lei Gao, Lei Zhao, Shengyu Li   +7 more
doaj   +1 more source

Preparation and Characterization of a Standardized Anticonvulsant Ginseng Rb Extract from Panax quinquefolius L. [PDF]

, 2011
A ginseng Rb extract (GRbE) containing three major ingredients of ginsenoside Rb1 (G-Rb1), ginsenoside Rb3 (G-Rb3) and ginsenoside Rd (G-Rd) has been shown to have anticonvulsant and neuroprotective activity.
Lian, Xiao-Yuan, Zhang, Zhizhen
core   +2 more sources

Anti-cancer effect and potential microRNAs targets of ginsenosides against breast cancer

Frontiers in Pharmacology, 2022
Breast cancer (BC) is one of the most common malignant tumor, the incidence of which has increased worldwide in recent years. Ginsenosides are the main active components of Panax ginseng C. A.
Meiling Fan, Mengyao Shan, Mengyao Shan, Xintian Lan, Xintian Lan, Xiaoxue Fang, Xiaoxue Fang, Dimeng Song, Dimeng Song, Haoming Luo, Haoming Luo, Donglu Wu, Donglu Wu   +12 more
doaj   +1 more source

Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7 [PDF]

, 2019
P2X7 receptors are important in the regulation of inflammatory responses and immune responses to intracellular pathogens such as Mycobacterium tuberculosis and Toxoplasma gondii.
Angulo, Jesus, Bidula, Stefan M, Cromer, Brett A, Stokes, Leanne, Walpole, Samuel   +4 more
core   +3 more sources

Classification of three types of ginseng samples based on ginsenoside profiles: appropriate data normalization improves the efficiency of multivariate analysis

Heliyon, 2022
Background: It is well known that ginsenosides are the main active ingredients in ginseng, and they have also been important indexes for assessing the quality of ginseng.
Yahui Li, Bingkun Yang, Wei Guo, Panpan Zhang, Jianghua Zhang, Jing Zhao, Qiao Wang, Wei Zhang, Xiaowei Zhang, Dezhi Kong   +9 more
doaj   +1 more source

Antifeedant and ovicidal activities of ginsenosides against Asian corn borer, Ostrinia furnacalis (Guenee).

PLoS ONE, 2019
IntroductionGinsenosides, including protopanaxdiol (PPD) and protopanaxtriol (PPT) type ginsenosides, have been identified as natural insecticidess.
Shuangli Liu, Xiaohui Wang, Yonghua Xu, Rui Zhang, Shengyuan Xiao, Yingping Wang, Lianxue Zhang   +6 more
doaj   +1 more source

Advances in the Production of Minor Ginsenosides Using Microorganisms and Their Enzymes

BIO Integration, 2020
Minor ginsenodes are of great interest due to their diverse pharmacological activities such as their anti-cancer, anti-diabetic, neuroprotective, immunomodulator, and anti-inflammatory effects. The miniscule amount of minor ginsenosides in ginseng plants
Almando Geraldi
doaj   +1 more source

Biotransformation of major ginsenosides in ginsenoside model culture by lactic acid bacteria

Journal of Ginseng Research, 2017
Background: Some differences have been reported in the biotransformation of ginsenosides, probably due to the types of materials used such as ginseng, enzymes, and microorganisms.
Seong-Eun Park, Chang-Su Na, Seon-A Yoo, Seung-Ho Seo, Hong-Seok Son   +4 more
doaj   +1 more source

Effects of gut microbiota on the pharmacokinetics of protopanaxadiol ginsenosides Rd, Rg3, F2, and compound K in healthy volunteers treated orally with red ginseng

Journal of Ginseng Research, 2020
Background: It is well recognized that gut microbiota is involved in the biotransformation of ginsenosides by converting the polar ginsenosides to nonpolar bioactive ginsenosides.
Jeon-Kyung Kim, Min Sun Choi, Woonhee Jeung, Jehyeon Ra, Hye Hyun Yoo, Dong-Hyun Kim   +5 more
doaj   +1 more source

Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD

Journal of Ginseng Research, 2023
Background: Hepatic lipid disorder impaired mitochondrial homeostasis and intracellular redox balance, triggering development of non-alcohol fatty liver disease (NAFLD), while effective therapeutic approach remains inadequate.
Zehong Yang, Yuanyuan Yu, Nannan Sun, Limian Zhou, Dong Zhang, HaiXin Chen, Wei Miao, Weihang Gao, Canyang Zhang, Changhui Liu, Xiaoying Yang, Xiaojie Wu, Yong Gao   +12 more
doaj   +1 more source