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Phytochemistry of ginsenosides: Recent advancements and emerging roles
Critical reviews in food science and nutrition, 2021Ginsenosides, a group of tetracyclic saponins, accounts for the nutraceutical and pharmaceutical relevance of the ginseng (Panax sp.) herb. Owing to the associated therapeutic potential of ginsenosides, their demand has been increased significantly in ...
Priyanka Chopra +5 more
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Ginsenosides in vascular remodeling: cellular and molecular mechanisms of their therapeutic action.
Pharmacological Research, 2021Evidence is mounting that abnormal vascular remodeling (VR) is a vital pathological event that precedes many cardiovascular diseases (CVD). This provides us with a new research perspective that VR can be a pivotal target for CVD treatment and prevention.
G. Zhu, J. Zuo, Lin Xu, Shu-qing Li
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Advancements in enzymatic biotransformation and bioactivities of rare ginsenosides：A Review.
Journal of BiotechnologyGinsenoside, the principal active constituent of ginseng, exhibits enhanced bioavailability and medicinal efficacy in rare ginsenosides compared to major ginsenosides.
Yanbo Hu +6 more
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Mitochondrial connection to ginsenosides
Archives of Pharmacal Research, 2020Mitochondria play an essential role in energy synthesis and supply, thereby maintaining cellular function, survival, and energy homeostasis via mitochondria-mediated pathways, including apoptosis and mitophagy. Ginsenosides are responsible for most immunological and pharmacological activities of ginseng, a highly beneficial herb with antioxidant, anti ...
Feng Wang, Yoon Seok Roh
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Ginseng Omics for Ginsenoside Biosynthesis
Current Pharmaceutical Biotechnology, 2021Ginseng, also known as the king of herbs, has been regarded as an important traditional medicine for several millennia. Ginsenosides, a group of triterpenoid saponins, have been characterized as bioactive compounds of ginseng. The complexity of ginsenosides hindered ginseng research and development both in cultivation and clinical research. Therefore,
Xianmei Yin +5 more
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Journal of Ethnopharmacology, 2020
ETHNOPHARMACOLOGICAL RELEVANCE Cyclophosphamide (CTX) is a first line chemotherapeutic agent, but often limited for its unstable therapeutic effect and serious side effects.
He Zhu +8 more
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ETHNOPHARMACOLOGICAL RELEVANCE Cyclophosphamide (CTX) is a first line chemotherapeutic agent, but often limited for its unstable therapeutic effect and serious side effects.
He Zhu +8 more
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Photochemistry and Photobiology, 2019
AbstractGinsenosides are compounds responsible for the primary pharmacological effects of American ginseng. Compound‐Y (C‐Y) is a minor ginsenoside and a metabolite of Panax ginseng. In this study, we investigated the protective effect of ginsenoside UVB‐irradiated NHDFs and its potential for use as an antihyperpigmentation agent through ginsenoside C ...
Xiao‐yi Liu +4 more
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AbstractGinsenosides are compounds responsible for the primary pharmacological effects of American ginseng. Compound‐Y (C‐Y) is a minor ginsenoside and a metabolite of Panax ginseng. In this study, we investigated the protective effect of ginsenoside UVB‐irradiated NHDFs and its potential for use as an antihyperpigmentation agent through ginsenoside C ...
Xiao‐yi Liu +4 more
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Conversion of Major Ginsenoside Rb1 to Ginsenoside F2 by Caulobacter leidyia
Biotechnology Letters, 2006Ginsenoside Rb1 is the most predominant ginsenoside in Panax species (ginseng) and the hydrolysis of this ginsenoside produces pharmaceutically active compounds. Caulobacter leidyia GP45, one of the isolates having strong beta-glucosidase-producing activity, converted ginsenoside Rb(1) to the active metabolites by 91%.
Le-Qin, Cheng +4 more
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Relationship between antimicrobial activity and amphipathic structure of ginsenosides
Industrial crops and products (Print), 2020Ginsenoside has a wide range of pharmacological activities, but little research has been conducted on its microbial pathogen inhibition and the relationship between its antimicrobial activity and saponin structure.
Peng Xue +6 more
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Journal of Food Engineering, 2012
Abstract This study developed a method for enriched separation of protopanaxatriol ginsenosides, malonyl ginsenosides and protopanaxadiol ginsenosides from Panax ginseng. The method began with targets extraction from herbal material, followed by HPD300 resins separation, then extracted by water-statured n-butanol.
Jianing Mi +5 more
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Abstract This study developed a method for enriched separation of protopanaxatriol ginsenosides, malonyl ginsenosides and protopanaxadiol ginsenosides from Panax ginseng. The method began with targets extraction from herbal material, followed by HPD300 resins separation, then extracted by water-statured n-butanol.
Jianing Mi +5 more
openaire +1 more source