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Ginseng Omics for Ginsenoside Biosynthesis
Current Pharmaceutical Biotechnology, 2021Ginseng, also known as the king of herbs, has been regarded as an important traditional medicine for several millennia. Ginsenosides, a group of triterpenoid saponins, have been characterized as bioactive compounds of ginseng. The complexity of ginsenosides hindered ginseng research and development both in cultivation and clinical research. Therefore,
Xianmei Yin +5 more
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Ginsenosides, potent inhibitors of sialyltransferase
Zeitschrift für Naturforschung C, 2020Abstract The overexpression of sialic acids and sialyltransferases (STs) during malignant transformation and progression could result in the aberrant sialylation of cancer cells. Therefore, interfering the sialic acid synthesis might be an effective pathway in cancer therapy. In this study, we assessed that the antitumor inhibitors of 20(
Wenxin, Huang +6 more
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Photochemistry and Photobiology, 2019
AbstractGinsenosides are compounds responsible for the primary pharmacological effects of American ginseng. Compound‐Y (C‐Y) is a minor ginsenoside and a metabolite of Panax ginseng. In this study, we investigated the protective effect of ginsenoside UVB‐irradiated NHDFs and its potential for use as an antihyperpigmentation agent through ginsenoside C ...
Xiao‐yi Liu +4 more
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AbstractGinsenosides are compounds responsible for the primary pharmacological effects of American ginseng. Compound‐Y (C‐Y) is a minor ginsenoside and a metabolite of Panax ginseng. In this study, we investigated the protective effect of ginsenoside UVB‐irradiated NHDFs and its potential for use as an antihyperpigmentation agent through ginsenoside C ...
Xiao‐yi Liu +4 more
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Applied Microbiology and Biotechnology, 2012
This study focused on the cloning, expression, and characterization of ginsenoside-transforming recombinant β-glucosidase from Actinosynnema mirum KACC 20028(T) in order to biotransform ginsenosides efficiently. The gene, termed as bglAm, encoding a β-glucosidase (BglAm) belonging to the glycoside hydrolase family 3 was cloned. bglAm consisted of 1,830
Cui, CH Cui, Chang-Hao +2 more
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This study focused on the cloning, expression, and characterization of ginsenoside-transforming recombinant β-glucosidase from Actinosynnema mirum KACC 20028(T) in order to biotransform ginsenosides efficiently. The gene, termed as bglAm, encoding a β-glucosidase (BglAm) belonging to the glycoside hydrolase family 3 was cloned. bglAm consisted of 1,830
Cui, CH Cui, Chang-Hao +2 more
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Biosynthesis and biotechnological production of ginsenosides
Biotechnology Advances, 2015Medicinal plants are essential for improving human health, and around 75% of the population in developing countries relies mainly on herb-based medicines for health care. As the king of herb plants, ginseng has been used for nearly 5,000 years in the oriental and recently in western medicines. Among the compounds studied in ginseng plants, ginsenosides
Kim, Y., Zhang, D., Yang, D.
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Synthesis of Ocotillol-Type Ginsenosides
The Journal of Organic Chemistry, 2016A total of 14 ocotillol-type ginsenosides were conveniently synthesized employing glycosylation of ocotillol sapogenin derivatives with glucosyl ortho-alkynylbenzoate donors under the promotion of a gold(I) catalyst as the key step. Relying on a rational protecting group strategy and the unexpected regioselectivity of the glycosylation of the 3,25-diol
Renzeng, Shen +4 more
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Effect of the structure of ginsenosides on the in vivo fate of their liposomes
Asian Journal of Pharmaceutical Sciences, 2022Jiaxuan Xia, Ying Zhu, Ru Zhang
exaly
Phytochemistry of ginsenosides: Recent advancements and emerging roles
Critical Reviews in Food Science and Nutrition, 2023Himanshu Chhillar +2 more
exaly