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Effects of Gintonin-Enriched Fraction in an Atopic Dermatitis Animal Model: Involvement of Autotaxin Regulation

open access: yesBiological and Pharmaceutical Bulletin, 2017
Ginseng extract has been used for prevention of atopic dermatitis (AD) in experimental animal models. However, little is known about its active ingredients and the molecular mechanisms underlying its anti-AD effects. Recently, we isolated a unique lysophosphatidic acid (LPA) receptor ligand, gintonin, from ginseng.
Seung-Yeol Nah   +2 more
exaly   +4 more sources
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Effects of gintonin-enriched fraction on hippocampal cell proliferation in wild-type mice and an APPswe/PSEN-1 double Tg mouse model of Alzheimer's disease

Neurochemistry International, 2016
We previously showed that gintonin, an exogenous lysophosphatidic acid (LPA) receptor ligand, attenuated β-amyloid plaque formation in the cortex and hippocampus, and restored β-amyloid-induced memory dysfunction. Both endogenous LPA and LPA receptors play a key role in embryonic brain development.
Seung-Yeol Nah   +2 more
exaly   +3 more sources

An Edible Gintonin Preparation from Ginseng

Journal of Ginseng Research, 2011
Seung-Yeol Nah   +2 more
exaly  

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