Results 151 to 158 of about 631 (158)
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Gintonin Suppresses Fat Accumulation in 3T3‐L1 cell
The FASEB Journal, 2020Obesity is caused by an imbalance between energy intake and energy expenditure. Furthermore, obesity is closely relational to many metabolic diseases such as type 2 diabetes and hypertension. Excess fat is stored in adipose tissue, which contains of fat cells, or adipocytes, which have an capacity for saving surplus energy in the form of lipid.
Jae-Hoon Oh +5 more
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Gintonin attenuates depressive-like behaviors associated with alcohol withdrawal in mice
Journal of Affective Disorders, 2017Panax ginseng Meyer extracts have been used to improve mood and alleviate symptoms of depression. However, little is known about the extracts' active ingredients and the molecular mechanisms underlying their reported anti-depressive effects.Gintonin is an exogenous lysophosphatidic acid (LPA) receptor ligand isolated from P. ginseng.
Hyeon-Joong, Kim +8 more
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Gintonin Administration is Safe and Potentially Beneficial in Cognitively Impaired Elderly
Alzheimer Disease & Associated Disorders, 2018Ginseng is a traditional herbal medicine that produces diverse physiological and pharmacological effects as a tonic, including the vitalization of body energy levels and producing beneficial effects to various diseases, including Alzheimer disease (AD).1,2 Gintonin is a recently identified active ...
Jangsup, Moon +6 more
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Brain, Behavior, and Immunity, 2021
Gintonin (GT), a glycolipoprotein fraction isolated from ginseng, exerts neuroprotective effects in models of neurodegenerative diseases such as Alzheimer's disease. However, the in vivo role of GT in multiple sclerosis (MS) has not been clearly resolved.
Jong Hee, Choi +5 more
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Gintonin (GT), a glycolipoprotein fraction isolated from ginseng, exerts neuroprotective effects in models of neurodegenerative diseases such as Alzheimer's disease. However, the in vivo role of GT in multiple sclerosis (MS) has not been clearly resolved.
Jong Hee, Choi +5 more
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Journal of Neurophysiology, 2015
Lysophosphatidic acid (LPA) is one of the well-characterized, ubiquitous phospholipid molecules. LPA exerts its effect by activating G protein-coupled receptors known as LPA receptors (LPARs). So far, LPAR signaling has been critically implicated during early development stages, including the regulation of synapse formation and the morphology of ...
Hoyong, Park +6 more
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Lysophosphatidic acid (LPA) is one of the well-characterized, ubiquitous phospholipid molecules. LPA exerts its effect by activating G protein-coupled receptors known as LPA receptors (LPARs). So far, LPAR signaling has been critically implicated during early development stages, including the regulation of synapse formation and the morphology of ...
Hoyong, Park +6 more
openaire +2 more sources
The American Journal of Chinese Medicine
Ginseng is a well-established functional food for brain health. However, its active ingredients have not yet been identified. Gintonin is a promising compound isolated from white/red ginseng. Its lysophosphatidic acid (LPA) is an exogenous G protein-coupled LPA receptor (LPAR) agonist.
Yujeong Ha +9 more
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Ginseng is a well-established functional food for brain health. However, its active ingredients have not yet been identified. Gintonin is a promising compound isolated from white/red ginseng. Its lysophosphatidic acid (LPA) is an exogenous G protein-coupled LPA receptor (LPAR) agonist.
Yujeong Ha +9 more
openaire +2 more sources
Neuroscience Letters, 2016
Ginseng has a long history of use as a tonic for restoration of vigor. One example of ginseng-derived tonic effect is that it can improve physical stamina under conditions of stress. However, the active ingredient and the underlying molecular mechanism responsible for the ergogenic effect are unknown.
Byung-Hwan, Lee +11 more
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Ginseng has a long history of use as a tonic for restoration of vigor. One example of ginseng-derived tonic effect is that it can improve physical stamina under conditions of stress. However, the active ingredient and the underlying molecular mechanism responsible for the ergogenic effect are unknown.
Byung-Hwan, Lee +11 more
openaire +2 more sources
Current Drug Targets, 2012
Ginseng, the root of Panax ginseng C.A. Meyer, is one of the oldest herbal medicines and induces a variety of physiological and pharmacological effects. Ginseng contains saponins called ginsenosides, which are considered as the biologically active ingredients in ginseng. Increasing evidences indicate that ginsenosides are non-selective in their actions
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Ginseng, the root of Panax ginseng C.A. Meyer, is one of the oldest herbal medicines and induces a variety of physiological and pharmacological effects. Ginseng contains saponins called ginsenosides, which are considered as the biologically active ingredients in ginseng. Increasing evidences indicate that ginsenosides are non-selective in their actions
openaire +2 more sources