Results 101 to 110 of about 434,998 (369)

Arheologija in GIS

Dela, 1992
V slovenski arheologiji je že od začetka osemdesetih let prisotna temeljna usmeritev v arheologijo pokrajine. Ta smer temelji na domeni, da je človek v preteklosti s svojim delovanjem pustil sledi v celotni pokrajini in da je zato potrebno v arheoloških raziskavah poselitve analizirati pokrajino in procese v njej kot enoti bivanja.
Janez Dular, Božidar Slapšak, Božidar Slapšak, Zoran Stančič, Zoran Stančič, Sneža Tecco-Hvala, Sneža Tecco-Hvala   +6 more
openaire   +3 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Pulse-compression ghost imaging lidar via coherent detection [PDF]

, 2016
Ghost imaging (GI) lidar, as a novel remote sensing technique,has been receiving increasing interest in recent years. By combining pulse-compression technique and coherent detection with GI, we propose a new lidar system called pulse-compression GI lidar.
arxiv   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Unconvergence of Very Large Scale GI Simulations [PDF]

, 2016
The giant impact (GI) is one of the most important hypotheses both in planetary science and geoscience, since it is related to the origin of the Moon and also the initial condition of the Earth. A number of numerical simulations have been done using the smoothed particle hydrodynamics (SPH) method. However, GI hypothesis is currently in a crisis.
arxiv   +1 more source

Processing BIM and GIS Models in Practice: Experiences and Recommendations from a GeoBIM Project in The Netherlands

ISPRS Int. J. Geo Inf., 2018
It is widely acknowledged that the integration of BIM and GIS data is a crucial step forward for future 3D city modelling, but most of the research conducted so far has covered only the high-level and semantic aspects of GIS-BIM integration.
K. Ohori, A. Diakité, T. Krijnen, H. Ledoux, J. Stoter   +4 more
semanticscholar   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Improving the accuracy of livestock distribution estimates through spatial interpolation

Geospatial Health, 2012
Animal distribution maps serve many purposes such as estimating transmission risk of zoonotic pathogens to both animals and humans. The reliability and usability of such maps is highly dependent on the quality of the input data. However, decisions on how
Ward Bryssinckx, Els Ducheyne, Bernard Muhwezi, Sunday Godfrey, Koen Mintiens, Herwig Leirs, Guy Hendrickx   +6 more
doaj   +1 more source

A Protocol to Convert Infrastructure Data from Computer-Aided Design (CAD) to Geographic Information Systems (GIS) [PDF]

arXiv, 2020
While many municipalities and organizations see value in converting infrastructure data from Computer-Aided Design (CAD) to Geographic Information System (GIS) format, the process can be complex, expensive, and time-consuming. Given that municipal employees often prefer to continue performing work in both CAD and GIS, depending on the type of work ...
arxiv  

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source