Results 41 to 50 of about 250,936 (311)
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
Usability engineering for GIS: learning from a screenshot [PDF]
, 2007 In this paper, the focus is on the concept of Usability Engineering for GIS – a set of techniques and methods that are especially suitable for evaluating the usability of GIS applications – which can be deployed as part of the development process.
Haklay, M., Zafiri, A.
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Conceptions of geographic information systems (GIS) held by senior geography students in Queensland [PDF]
, 2008 Geographical Information Systems (GIS) represent one of the major contributions to spatial analysis and planning of the new technologies. While teachers and others have viewed its potential contribution to geographical education as considerable, it has ...
West, Bryan A.
core +1 more source
From the cartographic gaze to contestatory cartographies [PDF]
, 2018 Rene Descartes declared in the 16th Century that the world was now dominated by the visual, a notion that would be seen as defining the Enlightenment (Descartes, cited in Potts, 2015).
Specht, D., Specht, D.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A proposal for defining land use planning spatial units based on hydrological processes [PDF]
GeoreviewIn Mexico, land-use policy is determined at the municipal level, where decisions regarding land use and purpose are made. These localized practices fundamentally shape territorial organization, though often without coherence, harmony, or sustainability ...
Néstor CORONA
doaj +1 more source