Results 51 to 60 of about 21,806 (266)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Development of a Conceptual Mapping Standard to Link Building and Geospatial Information

open access: yesISPRS International Journal of Geo-Information, 2018
This study introduces the BIM (building information modeling)-GIS (geographic information system) conceptual mapping (B2GM) standard ISO N19166 and proposes a mapping mechanism.
Taewook Kang
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Historical Maps in GIS

open access: yesGeographic Information Science & Technology Body of Knowledge, 2019
This chapter offers an overview on the use of historical maps in GIS for the study of environment and landscape. The chapter starts with an introduction on the value of historical maps, their “definition” and a short review of the main types of historical maps that can be useful in a GIS analysis.
openaire   +2 more sources

Using gis to map the evolution of the gaeltacht [PDF]

open access: yesIrish Geography, 2007
This paper describes the results of using digital mapping techniques (Geographic Information Systems - GIS) to facilitate the translation of historical legislative documents into large-scale (townland level) maps of the Gaeltacht. The boundaries of the Gaeltacht, within the error limits of the digital spatial data, indicate the changing spatial extent ...
Ni Bhrádaigh, Emer   +3 more
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

A Model for Complex Subsidence Causality Interpretation Based on PS-InSAR Cross-Heading Orbits Analysis

open access: yesRemote Sensing, 2019
Urban areas are subject to subsidence due to varying natural and anthropogenic causes. Often, subsidence is interpreted and correlated to a single causal factor; however, subsidence is usually more complex.
Bahaa Mohamadi, Timo Balz, Ali Younes
doaj   +1 more source

Home - About - Disclaimer - Privacy