Results 51 to 60 of about 1,388,907 (256)

Ixodid tick diversity and distribution across forest-fringe landscapes of the Western Ghats, India, with emphasis on Kyasanur Forest Disease vectors

open access: yesScientific Reports
The Western Ghats of India support a diverse assemblage of Ixodid ticks, including multiple vectors of Kyasanur Forest Disease (KFD), yet comprehensive data from forest-fringe landscapes outside recognised outbreak zones remain limited.
Hari Kishan Raju Konuganti   +3 more
doaj   +1 more source

Species Diversity and Molecular Screening of Pyrethroid Resistance Mediated by the Voltage-Gated Sodium Channel in Ixodid Ticks from Puducherry, India

open access: yesPathogens
Ticks are major ectoparasites of livestock in India, causing substantial economic losses and transmitting a wide range of pathogens. Control strategies rely heavily on synthetic pyrethroid acaricides; however, resistance associated with mutations in the ...
Kaja Hussain Jasmiminal   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Geographic Information System Tourism In Kudus [PDF]

open access: yes, 2012
the tourism service have been manually conducted in Kudus, in a such way they are served by books,brochure, poster,etc. for the every kind of tourists objects there.
Pratomo , Setiaji
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A Model for Complex Subsidence Causality Interpretation Based on PS-InSAR Cross-Heading Orbits Analysis

open access: yesRemote Sensing, 2019
Urban areas are subject to subsidence due to varying natural and anthropogenic causes. Often, subsidence is interpreted and correlated to a single causal factor; however, subsidence is usually more complex.
Bahaa Mohamadi, Timo Balz, Ali Younes
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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