Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression. [PDF]
, 2016 Gastrointestinal stromal tumors (GIST) arise within the interstitial cell of Cajal (ICC) lineage due to activating KIT/PDGFRA mutations. Both ICC and GIST possess primary cilia (PC), which coordinate PDGFRA and Hedgehog signaling, regulators of ...
Bardsley, Michael R +18 more
core +2 more sources
Journal of Family Medicine and Primary Care, 2022 The most common congenital gastrointestinal tract abnormality is Meckel's diverticulum, affecting 1% to 2% of the population. Meckel's diverticulum can sometimes house a gastrointestinal stromal tumor (GIST), which is a rare malignant tumor.
Aditya Patel +2 more
doaj +1 more source
Perforated GIST in Jejunum – A Rare Cause of Abdominal Cocoon [PDF]
Journal of Clinical and Diagnostic Research, 2014 Gastrointestinal stromal tumours [GISTs] are rare but they commonly arise in stomach, and small or large intestines. They are usually accompanied with gastrointestinal bleeding.
Usha M +3 more
doaj +1 more source
OncoImmunology, 2018 Correct temporal and spatial control of actin dynamics is essential for the cytotoxic T cell effector function against tumor cells. However, little is known whether actin engineering in tumor-targeted T cells can enhance their antitumor responses ...
Bu-Nam Jeon +9 more
doaj +1 more source
Get the gist? The effects of processing depth on false recognition in short-term and long-term memory [PDF]
, 2014 Gist-based processing has been proposed to account for robust false memories in the converging-associates task. The deep-encoding processes known to enhance verbatim memory also strengthen gist memory and increase distortions of long-term memory (LTM ...
Flegal, Kristin E. +1 more
core +1 more source
, 2013 A unified general theory of human concept learning based on the idea that humans detect invariance patterns in categorical stimuli as a necessary precursor to concept formation is proposed and tested.
Vigo , Dr. Ronaldo
core +1 more source
Gist gigante de alto riesgo: Reporte de caso y revisión de la literatura
Salud Uninorte, 2021 Los tumores del estroma gastrointestinal (GIST) son las neoplasias mesenquimales más frecuentes del tracto digestivo. Los criterios de estadificación del riesgo, como angioinvasion, tamaño, infiltración y el índice mitótico, permiten realizar un adecuado
JOSÉ DARÍO PORTILLO-MIÑO +3 more
doaj +1 more source
Role for targeted resection in the multidisciplinary treatment of metastatic gastrointestinal stromal tumor [PDF]
, 2019 The management of advanced gastrointestinal stromal tumors (GISTs) has evolved in the modern era due to the discovery of c-kit mutations and the development of tyrosine kinase inhibitors (TKIs).
Feizpour, Cyrus +4 more
core +1 more source
Paraneoplastic hypoglycaemia secondary to IGF-2 secretion from a metastatic gastrointestinal stromal tumour [PDF]
, 2020 We report the case of a 79-year-old male with previous history of non-Hodgkin's lymphoma in remission, who presented acutely to the Accident and Emergency department with recurrent episodes of hypoglycaemia.
Dimitriadis, Georgios K. +9 more
core +1 more source
Six years survival on imatinib with no disease progression after diagnosis of metastatic duodenal gastrointestinal stromal tumour: a case report [PDF]
, 2008 Introduction: A duodenal Gastrointestinal Stromal Tumour (GIST) is a rare finding and until recently advanced disease had a poor prognosis. A PubMed search revealed no reports of more than five years survival of inoperable GIST on chemotherapy with WHO ...
Amit Kumar Choudhury +10 more
core +3 more sources