Results 161 to 170 of about 202,656 (246)

Mesoporous Catalytic‐Adsorptive Nanoregulator Orchestrates Biofilm eDNA/LPS Disassembly and TLR9/TLR4 Immune Reprogramming to Resolve Diabetic Foot Infections

Advanced Science, EarlyView.
Chronic diabetic wounds are hindered by a “dual trap” of biofilm resistance and hyperinflammation. A mesoporous catalytic‐adsorptive nano‐regulator is developed to dismantle this barrier through simultaneous eDNA degradation and LPS sequestration. By silencing TLR4/9‐mediated signaling, the platform clears resilient pathogens and reprograms the immune ...
Junfeng Song, Yang Song, Xirui Huang, Xingjin Li, Lifei Gao, Yixiang Wang, Tianbao Zhu, Xiaomin Li, Shuai Wang, Tiancong Zhao, Dongyuan Zhao   +10 more
wiley   +1 more source

Wearing a noseclip improves nebulised aerosol delivery

Swiss Medical Weekly, 2001
GL Hall
doaj   +1 more source

Clinical risk factors of licorice-induced pseudohyperaldosteronism: a 2026-updated narrative review. [PDF]

Front Pharmacol
Yoshino T, Makino T.
europepmc   +1 more source

Interfacial Growth of 420 nm Ultrathin and Dense MOFs for Composite Electrolyte to Reduce Li+ Conduction Resistance and Inhibit Lithium Dendrite

Advanced Science, EarlyView.
In this work, an interfacial growth method using PVDF‐HFP enables controlled permeation of 2‐methylimidazole to react with Co2+, forming an ultrathin (420 nm) ZIF‐67 layer by precisely tuning the reaction time. This dense layer promotes lithium salt dissociation and suppresses dendrite growth, while its ultrathin nature reduces Li+ transport resistance,
Xinhong Qi, Zhaokai Rui, Shichen Zhang, Yihang Li, Ziyi Xin, Mengjuan Li, Lu Gao, Yuchen He, Xiaobin Jiang, Xiangcun Li, Gaohong He   +10 more
wiley   +1 more source

Glucuronolactone Alleviates Metabolic Stress Induced by High-Fat Diet in Turbot (<i>Scophthalmus maximus</i> L.). [PDF]

Antioxidants (Basel)
Wang P, Zheng L, Zhu L, Chen K, He D, Zhao J, Xu H, Mai K, Zhang Y.   +8 more
europepmc   +1 more source

Computation‐Guided Tunnel Engineering Enhances O2 Transport and H2O2 Resistance of Fe(II)/α‐Ketoglutarate‐Dependent Dioxygenases

Advanced Science, EarlyView.
This study presents a computational tunnel engineering strategy in Fe(II)/α‐ketoglutarate‐dependent dioxygenases (αKGDs) to enhance oxygen (O2) transport, an essential molecule for αKGDs, and limit hydrogen peroxide (H2O2) entry, an inhibitor from the αKG supply system.
Huan Liu, Lunjie Wu, Liying Mao, Songyin Zhao, Hu Liu, Shiyi Xin, Donglin Zhao, Jie Gu, Yan Xu, Xinye Wang, Yao Nie   +10 more
wiley   +1 more source

Bone Marrow-Derived Macrophages Loaded with Boron Carbide Nanoparticles Targeting the Glioblastoma Microenvironment for Boron Neutron Capture Therapy. [PDF]

Int J Nanomedicine
Rudawska A, Szczygieł A, Węgierek-Ciura K, Mierzejewska J, Kozień D, Żeliszewska P, Chaszczewska-Markowska M, Rusiniak P, Wątor K, Pędzich Z, Pajtasz-Piasecka E, Szermer-Olearnik B.   +11 more
europepmc   +1 more source

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

Advanced Science, EarlyView.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning, Ziqiang Zhou, Bangming Li, Hong Lu, Haoyang Wen, Zhoulong Huang, Gang Li, Ping Hu   +7 more
wiley   +1 more source

Chronic spontaneous urticaria as an autoimmune feature in common variable immunodeficiency. [PDF]

J Allergy Clin Immunol Glob
Korevaar ECA, Karim AF, Dalm VASH.
europepmc   +1 more source

PRMT5‐Dependent Stabilization of VPS34 Orchestrates Copper Trafficking to Shield Cancer Cells from Cuproptosis and Radiotherapy

Advanced Science, EarlyView.
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen, Ming‐Ying Xiao, Lan‐Lan Guo, Hao‐Yue Hu, Sui‐Xian Zhang, Bai‐Qiang Dong, Chen‐Fei Wu, Xia‐Hang Huang, Li Li, Run‐Zhe Chen, Yuan‐Yang Huang, Ying Jin, Hai Song, Ying Wang, Qi‐Wen Li, Ming Chen, Xuan Li, Yuan‐Yuan Chen   +17 more
wiley   +1 more source