Results 201 to 210 of about 202,656 (246)

Integrated metabolomic, network pharmacological, and molecular docking analyses comparing the therapeutic effects of Strobilanthes sarcorrhiza from different origins. [PDF]

Sci Rep
Xie W, Gao H, Zhu Z, Xu X, Ying Y, Yan Y, Ding L, Wu G.   +7 more
europepmc   +1 more source

Soft Hypoxia‐Adaptive Bioelectronics Integrating PEDOT:PSS/Polydopamine/Enzyme Biocomposites for Closed‐Loop Therapeutics of Chronic Wounds

Advanced Science, EarlyView.
Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu, Bowen Yang, Cao Qi, Zhijie Zhou, Haochen Zou, Anjum Qureshi, Xiao Zhao, Ting Li, Li Gao, Ye Tao, Gang Song, Pingqiang Cai, Zheng Li, Zhiyuan Liu, Dianpeng Qi, Ting Wang, Lianhui Wang   +16 more
wiley   +1 more source

Anti-arthritic efficacy of geraniol and methotrexate via miRNA-driven NLRP3 inflammasome suppression in rat adjuvant-induced arthritis. [PDF]

Inflammopharmacology
Gowayed MA, Hassan SA, Kamel MA, Helmy MW, El-Ganainy SO.   +4 more
europepmc   +1 more source

Synergistic p53 Pathway Activation Through Sono‐Gene Therapy Induced by Ultrasound‐Triggered Theranostic Mesoporous Nanoparticles

Advanced Science, EarlyView.
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Song Ning, Shuting Huang, Xiaoxuan Wang, Rui Liu, Yuye Fu, Suyun Li, Jie Li   +11 more
wiley   +1 more source

Fast-Dissolving Sodium Alginate-Based Microneedle Patch Integrating Tranilast and Glabridin-Loaded Nanoparticles for Dual-Action Hypertrophic Scar Therapy. [PDF]

Biomater Res
Younas A, Sohail M, Li Y, Zhou Q, Shen Y, Wang S, Shi Y, Shang Z, Shao C, Xiao J.   +9 more
europepmc   +1 more source

Fibrillarin Resists Cellular Senescence Via SIRT1‐Dependent Nicotinamide Metabolism and Its Inhibition Sensitizes Senolytic Therapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
FBL directly binds to and stabilizes SIRT1 by blocking its ubiquitin‐proteasome degradation, thereby sustaining nicotinamide metabolism and redox homeostasis to counteract cellular senescence in ESCC. Genetic and pharmacological suppression of FBL sensitizes tumor cells to senolytic therapy.
Xing Jin, Hong Liu, Ling Gao, Lei Liu, Ji‐Bin Liu, Xiaoxia Jin, Ming‐Song Wang, Dan Liu, Li Feng, Wen‐Lian Chen   +9 more
wiley   +1 more source

Clinical case-control study of the proprioceptive innervation of the pharynx in patients with obstructive sleep apnea. [PDF]

Braz J Otorhinolaryngol
Dantas GL, Cavalcante MLC, Gomes EF, Pimentel FLDS, Pimentel MD, Martins CDS.   +5 more
europepmc   +1 more source

Analysis of the Milk Oligosaccharides Spectrum and Sialylation Status of Milk from West African Dwarf Goat and East Friesian Sheep. [PDF]

ACS Omega
Isernhagen L, Galuska CE, Hoeflich A, Galuska SP.   +3 more
europepmc   +1 more source

Medium Complexity Modulates Kefiran Yield and Thermal Stability in Whey-Based Fermentations: Insights from Systematic Supplementation and Comprehensive Physicochemical Characterization. [PDF]

Polymers (Basel)
Martínez V, Arto-Paz F, Mamani M, Castro RI, Moris S, González DM, Valdés C.   +6 more
europepmc   +1 more source

Epidemiological and Virological Characteristics of H9N2 Avian Influenza Virus in Jiangsu Province, China, 2024. [PDF]

Viruses
Gao X, Yu H, Zhang N, Liu L, Tong J, Qi X, Huang H, Wang S, Li Z, Du Y, Zhu L.   +10 more
europepmc   +1 more source