Results 161 to 170 of about 2,632 (194)

Prenylated flavonoids from Sophora flavescens inhibit mushroom tyrosinase activity and modulate melanogenesis in murine melanoma cells and zebrafish. [PDF]

Front Pharmacol
Fan F, Chen L, Chen C, Ang S, Gutkowski J, Seeram NP, Ma H, Li D.   +7 more
europepmc   +1 more source

Neurotherapeutic effects of Vutiglabridin as a Paraoxonase-2 modulator in preclinical models of Parkinson's disease. [PDF]

Mol Neurodegener
An H, Kang S, Shin J, Kim P, Kim S, Im S, Kim JH, Lee KW, Kim DH, Park JH, Park MH, Lee J, Park SK, Kim KP, Lee HM, Lee JH, Choi LS, Jeon HJ, Kim SY, Hwang IY, Bhalla M, Won W, Park HS, Yoo SK, Lee BD, Lee CJ, Pak YK.   +26 more
europepmc   +1 more source

Bioactive substance contents and therapeutic potential for skin inflammation of an herbal gel containing Derris reticulata and Glycyrrhiza glabra. [PDF]

Pharm Biol
Sangkaew W, Sianglum W, Wunnoo S, Voravuthikunchai SP, Joycharat N.   +4 more
europepmc   +1 more source

Exploring the Role of Licorice and Its Derivatives in Cell Signaling Pathway NF-κB and MAPK. [PDF]

J Nutr Metab
Fatima I, Sahar A, Tariq A, Naz T, Usman M.   +4 more
europepmc   +1 more source

Optimization ultrasonic-assisted aqueous two-phase extraction of glabridin from licorice root and its activity against the foodborne pathogen MRSA. [PDF]

Food Chem X
Qu Q, Zhu Z, Zhao M, Wang H, Cui W, Huang X, Yuan Z, Zheng Y, Dong N, Liu Y, Wang H, Dong C, Zhang Z, Li Y.   +13 more
europepmc   +1 more source

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Glabridin inhibits dexamethasone-induced muscle atrophy

Archives of Biochemistry and Biophysics, 2019
Prevention of muscle wasting is known to contribute to improving the quality of life and extending a healthy life. Recently, we have reported that licorice flavonoid oil containing glabridin, which is a prenylated isoflavone, enhances muscle mass in mice.
Yasukiyo, Yoshioka, Yusuke, Kubota, Yumi, Samukawa, Yoko, Yamashita, Hitoshi, Ashida   +4 more
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Glabridin mitigates TiO2NP induced cognitive deficit in adult zebrafish

Neurochemistry International, 2023
Glabridin is extracted from the roots of Glycyrrhiza glabra, which has anti-oxidative and anti-inflammatory properties. We investigated the neuroprotective potential of Glabridin against the learning and memory deficit by triggering NRF2/HO-1 signaling in Titanium dioxide nanoparticles (TiO2NP) treated zebrafish.
Karamjeet Kaur, R.K. Narang, Shamsher Singh   +2 more
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Inhibitory mechanisms of glabridin on tyrosinase

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2016
Tyrosinase is an oxidase that is the rate-limiting enzyme for controlling the production of melanin in the human body. Overproduction of melanin could lead to a variety of skin disorders. Glabridin, an isoflavan, isolated from the root of Glycyrrhiza glabra Linn, has exhibited several pharmacological activities, including excellent inhibitory effects ...
Jianmin, Chen, Xiaojing, Yu, Yufeng, Huang   +2 more
openaire   +2 more sources

Fabrication and Evaluation of Glabridin Tip-loaded Dissolving Microneedles

Current Drug Delivery, 2021
Background: The clinical application of glabridin in treating skin diseases has been constrained by the limitations of its poor chemical stability and low skin permeability. Objective: Here, we describe Tip-loading Dissolving Microneedles (TDMNs) encapsulating drugs only in the tips of needles for glabridin delivery with improved stability and skin ...
Jianmin Chen, Meixia Wang, Mengnan Ran, Xinying Liu, Siwan Liu, Zhipeng Ruan, Nan Jin   +6 more
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Synthesis of glabridin derivatives as tyrosinase inhibitors

Archives of Pharmacal Research, 2009
A novel 3'',4''-dihydroglabridin was successfully prepared for studying on tyrosinase inhibitory activity. The result demonstrated that 3'',4''-dihydroglabridin exhibited higher activity than glabridin (IC(50) value = 11.40 microM), which is probably due to the 4-substituted resorcinol skeleton and the lacking of double bond between carbon atom 3'' and
Warunee, Jirawattanapong, Ekarin, Saifah, Chamnan, Patarapanich   +2 more
openaire   +2 more sources