Results 131 to 140 of about 5,595,222 (385)

Double‐Stranded DNA Reduces dsRNA Degradation in the Saliva and Significantly Enhanced RNAi‐Mediated Gene Silencing in Halyomorpha halys

open access: yesAdvanced Biology, EarlyView.
The invasive pest Halyomorpha halys causes significant crop losses requiring innovative pest control strategies such as RNA interference (RNAi). However, oral RNAi is largely ineffective in H. halys. This study shows that double‐stranded DNA (dsDNA) stabilizes dsRNA in saliva by inhibiting a highly expressed nuclease.
Venkata Partha Sarathi Amineni   +2 more
wiley   +1 more source

Exploring potential glacial lakes using geo-spatial techniques in Eastern Hindu Kush Region, Pakistan

open access: yesNatural Hazards Research
The study aimed to investigate the potential glacial lakes in response to climate change and the associated risk of glacial lake outburst floods (GLOFs).
Mariam Sarwar, Shakeel Mahmood
doaj   +1 more source

Persistence of full glacial conditions in the central Pacific until 15,000 years ago [PDF]

open access: yes, 2007
The magnitude of atmospheric cooling during the Last Glacial Maximum and the timing of the transition into the current interglacial period remain poorly constrained in tropical regions, partly because of a lack of suitable climate records.
Blard, P.-H.   +4 more
core   +3 more sources

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

open access: yesAdvanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo   +8 more
wiley   +1 more source

Tri-dimensional Model of the Radovna Glacier from the Last Glacial Period

open access: yesGeologija, 2016
The Radovna River Valley is located in the northwest of Slovenia, in the Julian Alps, and bounded by two plateaus – Pokljuka in the south and Mežakla in the north.
Luka Serianz
doaj   +1 more source

The northern sector of the last British ice sheet : maximum extent and demise [PDF]

open access: yes, 2008
Strongly divided opinion has led to competing, apparently contradictory, views on the timing, extent, flow configuration and decay mechanism of the last British Ice Sheet.
Bradwell, Tom   +11 more
core   +2 more sources

Our Latest Glacial Period [PDF]

open access: yesNature, 1891
I AM informed that near the Wash, and I suppose at other parts of the coast, the sea at low water is frozen into masses which with the rising tide become floes, and are urged backwards and forwards on the beach. This is, I believe, not a frequent occurrence on our shores, and it would be interesting if any observers could note whether the shingle or ...
openaire   +1 more source

Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats

open access: yesAdvanced Biology, EarlyView.
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang   +8 more
wiley   +1 more source

Was man in America in the Glacial period? [PDF]

open access: yesGeological Society of America Bulletin, 1903
Introduction The problem of the existence of man in America before or during the Glacial period has received fresh impetus by recent discoveries in the Missouri valley. The lively interest which these discoveries have aroused has led me to occupy the hour which is customarily allowed to the retiring President of the Society in a consideration of these
openaire   +2 more sources

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

open access: yesAdvanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso   +5 more
wiley   +1 more source

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