Results 81 to 90 of about 39,068 (264)
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Advanced Functional Materials, EarlyView.Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Post-glacial reshaping of Alpine topography induced by landsliding [PDF]
Earth Surface DynamicsIn steep alpine environments, successive glacial-interglacial cycles during the Quaternary led to multiple transient geomorphological phases.
C. Ariagno +4 more
doaj +1 more source
Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions
Advanced Functional Materials, EarlyView.An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park +10 more
wiley +1 more source
Pleistocene glacial variability as a chaotic response to obliquity forcing [PDF]
Climate of the Past, 2009 The mid-Pleistocene Transition from 40 ky to ~100 ky glacial cycles is generally characterized as a singular transition attributable to scouring of continental regolith or a long-term decrease in atmospheric CO<sub>2</sub> concentrations ...
P. Huybers
doaj
Advanced Functional Materials, EarlyView.While host structures are known to enhance the reversibility and safety of lithium metal deposition, their additional volume and weight often decrease the battery's energy density and specific energy. By combining a lightweight and porous scaffold of electrospun polymer with a thinner separator, this article demonstrates a simultaneous improvement of ...
Lennart Wichmann +6 more
wiley +1 more source
Ecosystem response to abrupt climate change during the last glacial period in Western Europe – The Lacustrine Sequence of Les Echets [PDF]
, 2009 Barbara Wohlfarth +4 more
openalex +1 more source
Advanced Functional Materials, EarlyView.A scalable one‐step copolymerization strategy is developed to produce low‐cost microporous ion exchange membranes that boost both the efficiency and lifespan of flow batteries. When combined with organic electrolytes in aqueous systems, these membranes enable safe and cheap flow battery energy storage, supporting the widespread integration of renewable
Jiaye Liu +7 more
wiley +1 more source
Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME
Advanced Functional Materials, EarlyView.A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li +10 more
wiley +1 more source
The deglaciation of the Ésera valley since the Maximum Ice Extent in the Pyrenees
GeogacetaThe Ésera valley is a narrow U-shape valley located in the Central Pyrenees. It has been modelled by the glacial activity during the Last Glacial Cycle.
Ixeia Vidaller +5 more
doaj +1 more source