Results 111 to 120 of about 28,257 (311)
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong +13 more
wiley +1 more source
Eccentricity Paces Late Pleistocene Glaciations
Late Pleistocene glacial terminations are caused by rising atmospheric CO2 occurring in response to atmospheric and ocean circulation changes induced by increased discharge from Northern Hemisphere ice sheets.
T. Blackburn, S. Kodama, G. Piccione
doaj +1 more source
Tri-dimensional Model of the Radovna Glacier from the Last Glacial Period
The Radovna River Valley is located in the northwest of Slovenia, in the Julian Alps, and bounded by two plateaus – Pokljuka in the south and Mežakla in the north.
Luka Serianz
doaj +1 more source
The Fraser Glaciation in the Cascade Mountains, southwestern British Columbia
The objective of this study is to reconstruct the history of glaciation from the start of Fraser (Late Wisconsinan) Glaciation to the end of deglaciation, for three areas in the Cascade Mountains.
Waddington, Betsy Anne
core
Diatom boron and boron isotope data from ODP Site 882 in the subarctic Pacific Ocean over the intensification of Northern Hemisphere glaciation (iNHG) at 2.73 ...
Rae, James W B +3 more
core +1 more source
SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition
The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhijing Zhang +9 more
wiley +1 more source
During the last decades, numerous local reconstructions based on field geology were developed at the University of Lausanne (UNIL). Team members of the UNIL participated in the elaboration of a 600 Ma to present global plate tectonic model deeply rooted ...
Christian Vérard +3 more
doaj +1 more source
The Droseraceae during the glaciations
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +1 more source
Duration and nature of the end-Cryogenian (Marinoan) glaciation [PDF]
The end-Cryogenian glaciation (Marinoan) is portrayed commonly as the archetype of snowball Earth, yet its duration and character remain uncertain.
Anthony R. Prave +12 more
core +1 more source
An assembly porous titanium/β‐TCP implant is developed to establish a spatially programmable osteogenic microenvironment for enhanced osseointegration. By decoupling mechanical support from bioactive ion release, localized ionic gradients generated from the β‐TCP module direct osteogenic activity and bone ingrowth toward the porous titanium framework ...
Heng Zhang +5 more
wiley +1 more source

