Results 111 to 120 of about 2,216 (259)

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Talin1 Adhesion Morphology and Colocalization With Tensin3 Are Largely Unaffected by Polyacrylamide Substrate Stiffness

Cytoskeleton, EarlyView.
ABSTRACT Cells sense the stiffness of their extracellular matrix (ECM) and adapt their behavior accordingly. We investigated how ECM stiffness affects the spatial organization of talin1, a key mechanosensitive focal adhesion protein. Using polyacrylamide (PA) hydrogels with tunable stiffnesses (0.2–188 kPa), we analyzed cell morphology, migration ...
Joanna Hajduk, Patrycja Twardawa, Sylwia Bobis‐Wozowicz, Marta Szewczyk, Zenon Rajfur, Zbigniew Baster   +5 more
wiley   +1 more source

Stochastic and deterministic processes influencing mountain mire diatom communities across spatial scales

Ecography, EarlyView.
Understanding how deterministic and stochastic processes influence the shape of microorganism community assembly across different spatial scales is essential for disentangling biodiversity patterns. Mires are nutrient‐poor and heterogeneous wetlands that form isolated habitats supporting highly diverse diatom assemblages, particularly in mountainous ...
Fernanda Gonzalez‐ Saldias, Angel Rain‐ Franco, Joan Gomà, Jorge García‐ Girón, Aaron Pérez‐ Haase   +4 more
wiley   +1 more source

Extrapolation strategy matters when transferring ecological niche models: new visualization tools for informed decisions

Ecography, EarlyView.
Abstract Ecological niche models (ENMs) are commonly used to predict species' potential distributions across space and time, allowing researchers and practitioners to assess invasion risk, estimate the impacts of future climate change, and reconstruct past distributions.
Gonzalo E. Pinilla‐Buitrago, Jamie M. Kass, Robert P. Anderson   +2 more
wiley   +1 more source

Global threats, local opportunities: ice‐related landforms provide refugia for high‐elevation plants and arthropods

Ecography, EarlyView.
Ice‐related landforms in mountain areas have been hypothesized to play a key role in the survival of cold‐adapted species threatened by climate change. However, our understanding of such landforms acting as refugia remains speculative. Here we analyse occurrence data, collected through a standardized sampling at 471 sampling points across the European ...
Mauro Gobbi, Barbara Valle, Mattia Brambilla, Duccio Tampucci, Marco Caccianiga   +4 more
wiley   +1 more source

A modular and programmable electrolyte platform: Covalently anchored thermochromic hydrogels for on‐demand electrochromic devices

FlexMat, EarlyView.
Developing stable, multifunctional hydrogel electrolytes without compromising performance presents a considerable challenge in the field. In this study, we introduce a material design strategy with broad applicability to combinations of functional polymeric segments, ionic monomers, and salts.
Manyu Liu, Jixiang Cui, Yulu Cai, Bin Deng, Yiqian Zhao, Chaohong Zhang, Shiguo Zhang, Hong Meng   +7 more
wiley   +1 more source

Heterogeneous Exhumation Mechanisms in Neoproterozoic Collisional Metamorphism: P–T Constraints From Pelotas and Punta del Este Terranes, Southern Brazil and Uruguay

Geological Journal, EarlyView.
Petrography, thermobarometry, and pseudosection modelling reveal peak metamorphic conditions of 3–7.5 kbar and 520°C–800°C in Tonian‐Cryogenian orthogneisses of the Dom Feliciano Belt. Metamorphic field gradients of 27°C/km–39°C/km and variable exhumation mechanisms support correlation of these units as remnants of a Himalayan‐type Piratini Orogeny ...
Thaiane Niederauer‐Santos, Carla Cristine Porcher, Daniel Triboli Vieira, Edinei Koester, Diego Jaldín, Karina Luengo, Luisa Caon   +6 more
wiley   +1 more source

Modeling the impacts of grazing management on livestock behavior and performance: A case study in the Peruvian Andes

Grassland Research, EarlyView.
Our modeling study shows that livestock management strongly influences grazing behavior and animal performance in the Peruvian Andes. Furthermore, adjusting stocking rates and improving animal distribution can enhance forage intake and body condition while increasing forage biomass.
Melody R. Zarria Samanamud, Randall B. Boone   +1 more
wiley   +1 more source

Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta‐lactamases

iMetaOmics, EarlyView.
An integrative metagenomic framework combining sequence, structural, and functional inference reveals a phylogenetically diverse and structurally conserved repertoire of putative beta‐lactamases across Antarctic soil microbiomes, with predominance of class A and subclass B3 enzymes and limited but detectable associations with mobile genetic elements ...
José Coche‐Miranda, Patricio Arros, Nicolás Canales, Camilo Berríos‐Pastén, Gastón Azziz, Rosalba Lagos, Julieta Orlando, Francisco P. Chávez, Andrés E. Marcoleta   +8 more
wiley   +1 more source

Warm‐wet transition restructures arid lake microbiomes and functional potential

iMetaOmics, EarlyView.
This study summarizes how a long‐term warm‐dry to warm‐wet transition restructures microbiomes and functional potential in Lake Bosten, an arid lake in northwestern China. Warm‐wet hydroclimatic change increased water level and hydrological connectivity, while decreasing salinity and total nitrogen.
Zhen Shen, Xingchen Li, Zhijun Gong, Yang Hu, Yongjiu Cai, Keqiang Shao, Guang Gao, Robbie M. Martin, Xiangming Tang   +8 more
wiley   +1 more source