Results 131 to 140 of about 2,106 (266)

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

ChemistryOpen, EarlyView.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda, Sami A. Al‐Hussain, Basant Farag, Mohamed El‐Naggar, Magdi E. A. Zaki, Emad S. A. Alhazmi, Adel S. M. Almohammadi, Sobhi M. Gomha   +7 more
wiley   +1 more source

Mountain glacier preservation with artificial interventions: A review. [PDF]

iScience
Wang F, Liu S, Wang L, Xu C, Meng H.
europepmc   +1 more source

The missing woodland story: Implications of 1700 years of stand‐scale change on ‘naturalness’ and managing remnant broadleaved woodlands

People and Nature, EarlyView.
Abstract Longer‐term perspectives—equivalent to the lifespans of long‐lived trees—are required to fully inform perceptions of ‘naturalness’ used in woodland conservation and management. Stand‐scale dynamics of an old growth temperate woodland are reconstructed using palaeoecological data.
Annabel Everard, J. Edward Schofield, Tim Mighall, Scott Timpany, Gill Plunkett   +4 more
wiley   +1 more source

Aeromagnetic map of Glacier Peak, Washington [PDF]

Open-File Report, 1982
openaire   +1 more source

Justice in coexistence: Pastoralism and large carnivores on the Qinghai‐Tibet Plateau

People and Nature, EarlyView.
Abstract The conflict between livestock husbandry and large carnivore conservation presents significant challenges in grassland ecosystems worldwide. Achieving sustainable coexistence among herders, livestock and large carnivores requires reconciling diverse perspectives and interests through equitable, inclusive and fair processes that address both ...
Yufang Gao, Yue Yu
wiley   +1 more source

Atmospheric Deposition of Local Mineral Dust Delivers Phosphorus to the Greenland Ice Sheet. [PDF]

Environ Sci Technol
McCutcheon J, McQuaid JB, Canha N, Barr SL, Lutz S, Roddatis V, Mayanna S, Tedstone AJ, Tranter M, Benning LG.   +9 more
europepmc   +1 more source

Synergistic Effect of Silanized Ramie Fiber and Montmorillonite Clay on the Mechanical, Thermal, and Dynamic‐Mechanical Properties of Polyester Composites

Polymer Composites, EarlyView.
Multiscale composite reinforced with silane‐modified ramie fiber and clay. ABSTRACT Multiscale polymer composites combining natural fibers and layered silicates can balance stiffness, toughness, and thermal stability when interfacial interactions are properly engineered.
Daniel Rossi Klein, Maria Eduarda Escher Maletz, Matheus Vinícius Gregory Zimmermann, Ademir José Zattera, Daiane Romanzini   +4 more
wiley   +1 more source

Younger Dryas glacier advances in the tropical Andes driven by increased precipitation. [PDF]

Sci Rep
Glasser NF, Harrison S, Wilson R, Wood J, Peacey M, Rood D, Nichols K, Colucci RR, Del Gobbo C, Securo A, Torres JC, Riveros C, Jara HW, Melgarejo E, Villafane H, Cosi M.   +15 more
europepmc   +1 more source

Tuning adsorption and morphology in poly(glutamic acid) via controlled acidic partial deprotection

Polymer International, EarlyView.
Partial deprotection of poly(glutamic acid) generates morphologies and assemblies that match fully deprotected polypeptides in small‐molecule adsorption, extending to block copolypeptides with pH‐dependent effects. Abstract Synthetic polypeptides prepared from N‐carboxyanhydride (NCA) monomers are important platforms for environmental and medical ...
Hunter Wood, Stella Trickett, Joseph Dosch, Farin Weinger, Dan Flaherty, Stefanie Sydlik   +5 more
wiley   +1 more source

10,000 years of centennially-resolved climate and sea-level change archived in Svalbard beach-ridge system. [PDF]

Sci Rep
Strzelecki MC, Lindhorst S, Hein CJ, van der Bilt WGM, Kivimaki KE, Kavan J.   +5 more
europepmc   +1 more source