Results 21 to 30 of about 2,057 (172)

Trombastenia de Glanzmann. Histerectomia vaginal de urgência tratada com factor VIIa recombinante.

Acta Médica Portuguesa, 2004
In the present article, regarding a clinical case of Thrombasthenia of Glanzmann with severe anaemia by menometrorrhagia, the authors propose the vaginal hysterectomy and the administration of the recombinant factor VIIa on the immediate pre and ...
João S Mairos, Ana C Bernardo, Anabela R Neves, Ana P Campos, Filomena P Nunes, João S Saraiva, Maria C Trinidade, Alcides H Pereira, Ana Marques Pereira, Carlos B Falcão, Hélio Retto   +10 more
doaj   +1 more source

Glanzmann thrombasthenia complicated by frequent myeloproliferative neoplasm‐related thromboembolism: thrombosis occurring regardless of αIIbβIII integrin deficiency

Clinical Case Reports, 2021
A patient with Glanzmann Thrombasthenia developed recurrent venous thrombosis with a JAK2 positive myeloproliferative neoplasm. This indicates that the platelet aIIbβIII integrin has no role in venous thrombosis. We discuss the other potential mechanisms
Roger E. G. Schutgens, Rolf T. Urbanus
doaj   +1 more source

A rare case report on Glanzmann thrombasthenia

National Journal of Physiology, Pharmacy and Pharmacology, 2017
Glanzmann thrombasthenia (GT) is a rare inherited blood clotting disorder characterized by the impaired function of platelets that are essential for proper blood clotting and can lead to prolonged bleeding time. Patient with GT may experience menorrhagia,
Somy Cherian, Preenumol Thomas, Roshni PR   +2 more
doaj   +1 more source

Leukocyte adhesion defects Type III: A rare association of primary immunodeficiency and platelet functional defect

Journal of Applied Hematology, 2022
Leukocyte adhesion defect (LAD) Type III is an extremely rare disease, which presents with severe infections and a Glanzmann thrombasthenia-like bleeding phenotype.
Anand Prakash
doaj   +1 more source

Cytoskeletal perturbation leads to platelet dysfunction and thrombocytopenia in variant forms of Glanzmann thrombasthenia

Haematologica, 2016
Several patients have been reported to have variant dominant forms of Glanzmann thrombasthenia, associated with macrothrombocytopenia and caused by gain-of-function mutations of ITGB3 or ITGA2B leading to reduced surface expression and constitutive ...
Loredana Bury, Emanuela Falcinelli, Davide Chiasserini, Timothy A. Springer, Joseph E. Italiano, Paolo Gresele   +5 more
doaj   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Smartphone‐Based Teledentistry to Support Clinical Triage and Risk‐Informed Dental Care in Patients With Inherited Bleeding and Haemoglobin Disorders: A Cross‐Sectional Diagnostic Agreement Study

Haemophilia, EarlyView.
ABSTRACT Introduction Patients with inherited bleeding and haemoglobin disorders face barriers to accessing timely dental care, increasing the risk of untreated oral disease and complications related to invasive procedures. Aim To evaluate the agreement between smartphone‐based asynchronous teledentistry and face‐to‐face examination for oral conditions,
Victor Cordeiro da Silva, Carolina Mendes Frusca do Monte, Leandro Tavares da Silva, Gabriela Silva Almeida, Claudia Santos Lorenzato, José Vitor Nogara Borges de Menezes, Fabian Calixto Fraiz, Cassius Carvalho Torres‐Pereira   +7 more
wiley   +1 more source

FREQUENCY OF INHERITED PLATELE FUNCTION DISORDERS–ARMED FORCES INSTITUTE OF PATHOLOGY EXPERIENCE

Pakistan Armed Forces Medical Journal, 2020
Objective: To determine the frequency and clinical features of inherited platelet function disorders diagnosed at Armed Forces Institute of Pathology. Study Design: Cross sectional study.
Saira Irum, Helen Mary Robert, Asad Mahmood, Rafia Mahmood, Ayesha Khurshid, Mansoor Ishaq   +5 more
doaj   +4 more sources

Glanzmann thrombasthenia and its perioperative management in head trauma: A rare and challenging situation

Journal of Neuroanaesthesiology and Critical Care, 2016
Glanzmann thrombasthenia is a rare inherited coagulation disorder, manifesting itself in early childhood as bleeding episodes. The patients with this disease may present with uncontrollable bleeding following trauma.
Neeraj Kumar, Abdul A. Khan, Nilesh Kumar, Ashish Bindra, Charu Mahajan, Keshav Goyal   +5 more
doaj   +1 more source

Monozygotic twin cases of endometriosis with Glanzmann thrombasthenia: a case report and review of literature

Orphanet Journal of Rare Diseases, 2023
Background Glanzmann thrombasthenia (GT) is a rare bleeding disorder with a high prevalence in communities where consanguineous marriages are mainstream.
Samaneh Rokhgireh, Abolfazl Mehdizadehkashi, Shahla Chaichian, Mohammad Faranoush, Fardis Salmanpour, Noosha Samieefar, Roya Derakhshan   +6 more
doaj   +1 more source