Results 41 to 50 of about 3,924,160 (300)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Scientific ReportsA series of glass samples with the nominal composition 65SiO2 - (22.5-x) Li2O − 12.5Al2O3 - xTiO2, where x varies as 2.5, 5, 7.5, and 10 mol%, were synthesized using the conventional melt-quenching technique.
M. A. Marzouk +7 more
doaj +1 more source
Boletín de la Sociedad Española de Cerámica y Vidrio, 2018 In this work we demonstrated the necessity to complement the techniques XPS and IGC-ID to evaluate the surface properties of the SiC materials. We have studied four SiC materials with different particles sizes being 3 of them of a Si/C ratio close to the
Aitana Tamayo +3 more
doaj +1 more source
Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. [PDF]
, 2018 Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and ...
GLASS Consortium
core
Thermal breakage of window glass in room fires conditions - Analysis of some important parameters [PDF]
, 1997 In a compartment fire, the breakage and possible fallout of a window glass has a significant impact on the fire dynamics. The thermal breakage of glass depends on various parameters such as glass type, edge shading, edges conditions and constraints on ...
Siaka Dembele +36 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The Realities of K-12 Virtual Education [PDF]
, 2009 In a decade, virtual education in its contemporary form of asynchronous, computer-mediated interaction between a teacher and students over the Internet has grown from a novelty to an established mode of education that may provide all or part of formal ...
Gene V. Glass
core +3 more sources
Early Warning Analysis for Social Diffusion Events [PDF]
, 2012 There is considerable interest in developing predictive capabilities for social diffusion processes, for instance to permit early identification of emerging contentious situations, rapid detection of disease outbreaks, or accurate forecasting of the ...
Colbaugh, Richard, Glass, Kristin
core +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Ultra-Broadband Plasmon Resonance in Gold Nanoparticles Precipitated in ZnO-Al2O3-SiO2 Glass
CeramicsOptical materials with a tunable localized surface plasmon resonance (LSPR) are of great interest for applications in photonics and optoelectronics. In the present study, we explored the potential of generating an LSPR band with an ultra-broad range of ...
Georgiy Shakhgildyan +9 more
doaj +1 more source