Results 71 to 80 of about 1,695,620 (314)

Glasses and Glass Ceramics [PDF]

open access: yesNature, 1968
The emergence of synthetic ceramics as a prominent class of materials with a unique combination of properties has been an important part of the materials-science scene over the past 20 years. These 'high-technology' ceramics have varied applications in areas utilizing their exceptional mechanical, thermal, optical, magnetic or electronic properties.
openaire   +2 more sources

Effect of B2O3 on structure, properties and tube forming of medium borosilicate pharmaceutical glasses

open access: yesJournal of Asian Ceramic Societies
At recent, medium borosilicate glass is most commonly used as the main material of medical glass at home and abroad. In this paper the influence of B2O3 on the structure and properties of medium borosilicate medical glass was studied in this paper.
Changqing Li   +7 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

General catalogue of illuminating glassware and lighting fixtures for commercial and residential lighting / manufactured by The Crown Crystal Glass Co. [PDF]

open access: yes, 1920
Cover title: Lighting ware by Crown Crystal Glass Co.; Electronic reproduction. Canberra, A.C.T.
Crown Crystal Glass Co.
core  

Heat transfer analysis of a glass furnace sidewall [Conference paper] [PDF]

open access: yes, 2016
Furnace Solution Conference 2016 -- 2016-06-09 -- Stoke-on-Trent -- 166171The temperature distributions in the refractory sidewalls of a glass melting furnace are important in predicting the life time of a glass tank.
Aydın, Mevlüt, Ozkaynak, Fahri T.
core   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Influence of edge flaws on failure strength of glass [PDF]

open access: yes, 2011
Glass is a challenging building material, among others due to the difficulty of defining its strength-related parameters. One of the main parameters influencing the strength of glass is the flaw population created at the edges of glass elements by ...
Belis, Jan   +3 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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