Results 81 to 90 of about 2,212,907 (348)
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Influence of Temperature on Laminated Glass Performances Assembled with Various Interlayers
The increasing demand for use of laminated glass in building facades is the driving force for new interlayers testing and their implementation.
M. Novotny, B. Poot
doaj +1 more source
Friction control of elastic materials on glass by means of textured surfaces
To investigate the friction behaviors of elastomer and polyacetal writing tips sliding on various textured glass surfaces, the influences of the pitch size and height of sub-millimeter to millimeter sized texture on friction were examined via ...
Naoki Fujita+4 more
doaj +1 more source
Vitrimers: permanent organic networks with glass-like fluidity
Vitrimers possess the unique property that they are malleable while being permanently cross-linked. This mini-review highlights the existing vitrimer systems in the period 2011–2015 with the main focus on their chemical origin.
W. Denissen+2 more
semanticscholar +1 more source
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira+14 more
wiley +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh+7 more
wiley +1 more source
Two series of glasses were synthesized by conventional rapid melt-quench method for different glass systems 55[(PbxBi1-x).TiO3]-44[2SiO2B2O3] and 65[(PbxBi1-x).TiO3]-34[2SiO2B2O3] doped with 1 mole percent of La2O3. X-ray diffraction study of synthesized
Abhishek Madheshiya+2 more
doaj +1 more source